MPD: Phenotype measures mapped to MP:0002078, abnormal glucose homeostasis

Phenotype measures associated with ontology term
MP:0002078 'abnormal glucose homeostasis'

All measures in this list are mapped to the ontology descendants of MP:0002078. None are mapped to MP:0002078 directly.

MP:0000188 abnormal circulating glucose level
MP:0001560 abnormal circulating insulin level
MP:0001758 abnormal urine glucose level
MP:0003564 abnormal insulin secretion
MP:0003565 abnormal glucagon secretion
MP:0005291 abnormal glucose tolerance
MP:0005331 insulin resistance
MP:0005437 abnormal glycogen level
MP:0013277 abnormal fasting circulating glucose level

This MP term has been mapped to these MPD phenotype measurements to help users find relevant data. It should be noted that MPD measurements typically have a mixture of high-end, low-end and "normal" readings.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	Sex	Age	Sample Size (Avg)	Year
Attie2:76	Attie2	metabolic panel	high-fat high-sucrose diet	plasma glucose after diet (4h fast) [mg/dL] GLU 110693 wk: 6 10 14 22	DO population	both	10-26wks	N=250	2018

Attie2:80	Attie2	hormone quantification	high-fat high-sucrose diet	plasma insulin after diet (4h fast) [ng/mL] INS 110697 wk: 6 10 14 22	DO population	both	10-26wks	N=250	2018

Attie2:89	Attie2	glucose tolerance	high-fat high-sucrose diet	glucose level at t=0 after ~14 wks on diet (4h fast) [mg/dL] GLU_0min 110706	DO population	both	18wks	N=248	2018

Attie2:90	Attie2	glucose tolerance	high-fat high-sucrose diet	insulin level at t=0 after ~14 wks on diet (4h fast) [ng/mL] INS_0min 110707	DO population	both	18wks	N=248	2018

Attie2:91	Attie2	glucose tolerance	high-fat high-sucrose diet	HOMA-IR: (glucose x insulin) / 405 at t=0 after ~14 wks on diet (4h fast) HOMA_IR 110708	DO population	both	18wks	N=248	2018

Attie2:92	Attie2	glucose tolerance	high-fat high-sucrose diet	HOMA-B: (360 x insulin) / (glucose minus 63) at t=0 after ~14 wks on diet (4h fast) HOMA_B 110709	DO population	both	18wks	N=246	2018

Attie2:93	Attie2	glucose tolerance	high-fat high-sucrose diet	glucose area under curve (AUC) after ~14 wks on diet without correction for baseline difference (4h fast) [AUC] GLU_AUC_tot 110710	DO population	both	18wks	N=248	2018

Attie2:94	Attie2	glucose tolerance	high-fat high-sucrose diet	glucose area under curve (AUC) after ~14 wks on diet after subtraction of glucose at t=0 (4h fast) [AUC] GLU_AUC_adj 110711	DO population	both	18wks	N=248	2018

Attie2:96	Attie2	glucose tolerance	high-fat high-sucrose diet	insulin area under curve (AUC) after ~14 wks on diet after subtraction of insulin at t=0 (4h fast) [AUC] INS_AUC_adj 110713	DO population	both	18wks	N=248	2018

Attie2:100	Attie2	hormone quantification	high-fat high-sucrose diet	amount of insulin per islet after diet [ng/mL] INS_per_islet 110717	DO population	both	19-26wks	N=241	2018

Attie2:101	Attie2	hormone quantification	high-fat high-sucrose diet	whole pancreas insulin content after diet (insulin content per islet times number of islets) [ng/mL] INS_per_pancreas 110718	DO population	both	19-26wks	N=241	2018

Attie2:102	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to glucose [ng/mL] INS_GLU 110719 3.3 mM 8.3 mM 16.7 mM	DO population	both	19-26wks	N=242	2018

Attie2:105	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl [ng/mL] INS_GLU3p3_KCl 110722	DO population	both	19-26wks	N=240	2018

Attie2:106	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1 [ng/mL] INS_GLU8p3_GLP1 110723	DO population	both	19-26wks	N=240	2018

Attie2:107	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus a mix of amino acids (Ala, Glu, Leu) [ng/mL] INS_GLU8p3_AA 110724	DO population	both	19-26wks	N=240	2018

Attie2:108	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose plus 0.5 mM palmitic acid [ng/mL] INS_GLU16p7_PA 110725	DO population	both	19-26wks	N=240	2018

Attie2:109	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU8p3_fc_G3p3 110726	DO population	both	19-26wks	N=240	2018

Attie2:110	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 16.7 mM glucose, expressed as fold-change over that observed with 3.3.mM glucose [ratio] INS_GLU16p7_fc_G3p3 110727	DO population	both	19-26wks	N=240	2018

Attie2:111	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 3.3 mM glucose plus 40 mM KCl, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU3p3__KCl_fc_G3p3 110728	DO population	both	19-26wks	N=240	2018

Attie2:112	Attie2	hormone quantification	high-fat high-sucrose diet	ex vivo insulin secretion after diet in response to 8.3 mM glucose plus 100 nM GLP-1, expressed as fold-change over that observed with 3.3 mM glucose [ratio] INS_GLU8p3_GLP1_fc_G3p3 110729	DO population	both	19-26wks	N=240	2018

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