Project measure / variable:   GMC06   GLU

ID, description, units MPD:55511   GLU   glucose (plasma GLU, 16h fast)   [mmol/L]  
Data set, strains GMC06   inbred   5 strains     sex: both     age: 10-11wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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GMC06 - glucose (plasma GLU, 16h fast)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested5 strains5 strains
Mean of the strain means8.76   mmol/L 8.69   mmol/L
Median of the strain means8.07   mmol/L 8.21   mmol/L
SD of the strain means± 2.27 ± 2.62
Coefficient of variation (CV)0.260 0.302
Min–max range of strain means5.96   –   11.8   mmol/L 5.77   –   12.7   mmol/L
Mean sample size per strain16.6   mice 16.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.3204 0.3204 0.1277 0.7213
strain 4 770.0512 192.5128 76.706 < 0.0001
sex:strain 4 17.8246 4.4562 1.7755 0.1366
Residuals 153 383.9915 2.5097


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5.96 1.31   16 0.327 0.219 4.58, 9.14 -1.23
129S1/SvImJ m 5.77 0.574   16 0.143 0.0995 4.85, 6.95 -1.11
A/J f 10.2 1.68   16 0.421 0.165 6.78, 12.9 0.64
A/J m 9.5 1.41   16 0.352 0.148 6.91, 12.3 0.31
C57BL/6J f 7.75 1.3   16 0.326 0.168 5.92, 10.6 -0.44
C57BL/6J m 8.21 1.53   16 0.383 0.187 5.26, 10.4 -0.18
NOD/ShiLtJ f 8.07 1.51   18 0.356 0.187 5.27, 10.0 -0.3
NOD/ShiLtJ m 7.26 1.04   16 0.26 0.143 5.96, 9.08 -0.54
NZO/HlLtJ f 11.8 2.47   17 0.599 0.209 6.53, 15.4 1.34
NZO/HlLtJ m 12.7 2.13   16 0.531 0.167 8.61, 17.1 1.53


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5.9644 0.3961 6.7468 5.1819
129S1/SvImJ m 5.7675 0.3961 6.5499 4.9851
A/J f 10.1888 0.3961 10.9712 9.4063
A/J m 9.4975 0.3961 10.2799 8.7151
C57BL/6J f 7.7513 0.3961 8.5337 6.9688
C57BL/6J m 8.2106 0.3961 8.9931 7.4282
NOD/ShiLtJ f 8.0689 0.3734 8.8066 7.3312
NOD/ShiLtJ m 7.2581 0.3961 8.0406 6.4757
NZO/HlLtJ f 11.8329 0.3842 12.592 11.0739
NZO/HlLtJ m 12.7306 0.3961 13.5131 11.9482


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 5.8659 0.2801 6.4192 5.3127
A/J both 9.8431 0.2801 10.3964 9.2899
C57BL/6J both 7.9809 0.2801 8.5342 7.4277
NOD/ShiLtJ both 7.6635 0.2722 8.2012 7.1258
NZO/HlLtJ both 12.2818 0.2759 12.8269 11.7367




  GWAS USING LINEAR MIXED MODELS