Project measure / variable:   Schonfeld1   Insulin

ID, description, units MPD:32311   Insulin   insulin level (plasma), 30 min post injection in glucose tolerance test (10% glucose i.p., 5h fast)   [ng/mL]  
Data set, strains Schonfeld1   inbred   10 strains     sex: both     age: 9-13wks
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  STRAIN COMPARISON PLOT
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Schonfeld1 - insulin level (plasma), 30 min post injection in glucose tolerance test (10% glucose i.p., 5h fast)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains9 strains
Mean of the strain means0.372   ng/mL 0.429   ng/mL
Median of the strain means0.241   ng/mL 0.414   ng/mL
SD of the strain means± 0.346 ± 0.356
Coefficient of variation (CV)0.931 0.830
Min–max range of strain means0.00980   –   0.979   ng/mL 0.0328   –   1.17   ng/mL
Mean sample size per strain5.0   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1824 0.1824 3.9408 0.0509
strain 8 8.7146 1.0893 23.5313 < 0.0001
sex:strain 8 1.2179 0.1522 3.2887 0.003
Residuals 72 3.3331 0.0463


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ f 0.119 0.0581   5 0.026 0.487 0.06, 0.189 -0.73
129X1/SvJ m 0.0588 0.0255   5 0.0114 0.434 0.02, 0.08 -1.04
AKR/J f 0.672 0.184   5 0.0823 0.274 0.375, 0.866 0.87
BALB/cByJ f 0.272 0.0518   5 0.0232 0.191 0.196, 0.34 -0.29
BALB/cByJ m 0.746 0.373   5 0.167 0.5 0.415, 1.32 0.89
C3H/HeJ f 0.398 0.291   5 0.13 0.731 0.139, 0.784 0.08
C3H/HeJ m 0.303 0.064   5 0.0286 0.211 0.222, 0.385 -0.35
C57BL/6ByJ f 0.21 0.126   5 0.0565 0.602 0.026, 0.375 -0.47
C57BL/6ByJ m 0.414 0.148   5 0.0662 0.358 0.267, 0.629 -0.04
C57BL/6J f 0.166 0.0859   5 0.0384 0.518 0.054, 0.261 -0.59
C57BL/6J m 0.451 0.29   5 0.13 0.644 0.246, 0.963 0.06
DBA/1LacJ f 0.856 0.412   5 0.184 0.481 0.365, 1.46 1.4
DBA/1LacJ m 0.485 0.104   5 0.0467 0.215 0.348, 0.637 0.16
NZB/BlNJ f 0.0098 0.0107   5 0.0048 1.1 0.005, 0.029 -1.05
NZB/BlNJ m 0.0328 0.0174   5 0.0078 0.532 0.025, 0.064 -1.11
PL/J f 0.979 0.426   5 0.19 0.435 0.365, 1.4 1.75
PL/J m 1.17 0.296   5 0.132 0.254 0.846, 1.52 2.08
SWR/J f 0.037 0.0176   5 0.00788 0.476 0.025, 0.064 -0.97
SWR/J m 0.202 0.138   5 0.0616 0.681 0.041, 0.37 -0.64


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ f 0.1194 0.0962 0.3112 0.0
129X1/SvJ m 0.0588 0.0962 0.2506 0.0
BALB/cByJ f 0.2718 0.0962 0.4636 0.08
BALB/cByJ m 0.7458 0.0962 0.9376 0.554
C3H/HeJ f 0.3982 0.0962 0.59 0.2064
C3H/HeJ m 0.3032 0.0962 0.495 0.1114
C57BL/6ByJ f 0.21 0.0962 0.4018 0.0182
C57BL/6ByJ m 0.4136 0.0962 0.6054 0.2218
C57BL/6J f 0.166 0.0962 0.3578 0.0
C57BL/6J m 0.4508 0.0962 0.6426 0.259
DBA/1LacJ f 0.856 0.0962 1.0478 0.6642
DBA/1LacJ m 0.485 0.0962 0.6768 0.2932
NZB/BlNJ f 0.0098 0.0962 0.2016 0.0
NZB/BlNJ m 0.0328 0.0962 0.2246 0.0
PL/J f 0.9788 0.0962 1.1706 0.787
PL/J m 1.1652 0.0962 1.357 0.9734
SWR/J f 0.037 0.0962 0.2288 0.0
SWR/J m 0.2022 0.0962 0.394 0.0104


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ both 0.0891 0.068 0.2247 0.0
BALB/cByJ both 0.5088 0.068 0.6444 0.3732
C3H/HeJ both 0.3507 0.068 0.4863 0.2151
C57BL/6ByJ both 0.3118 0.068 0.4474 0.1762
C57BL/6J both 0.3084 0.068 0.444 0.1728
DBA/1LacJ both 0.6705 0.068 0.8061 0.5349
NZB/BlNJ both 0.0213 0.068 0.1569 0.0
PL/J both 1.072 0.068 1.2076 0.9364
SWR/J both 0.1196 0.068 0.2552 0.0




  GWAS USING LINEAR MIXED MODELS