MPD: Project measures / variables set: Naggert1 GLU

Project measures / variables set: Naggert1 GLU

ID, description, units	MPD:14302 GLU glucose (plasma GLU, 4h fast) [mg/dL] high-fat diet study
Measures	• baseline • after 17wks on diet • Δchange
Data set, strains	Naggert1 inbred w/CC7 43 strains sex: both age: 7-9wks
Procedure	metabolic panel
Comparison	repeated measures, baseline then treated, same cohort
Ontology mappings	VT:0000188 blood glucose amount MA:0002501 plasma MP:0000188 abnormal circulating glucose level

Values Means Δ Means Z-scores

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Naggert1 - glucose (plasma GLU, 4h fast)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary "within" = Within error "between" = Between Error (Animal ID)

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
between sex	1	75904.4722	75904.4722	57.6101	< 0.0001
between strain	38	754907.5473	19865.9881	15.0779	< 0.0001
between sex:strain	38	105511.8071	2776.6265	2.1074	0.0002
between Residuals	589	776040.0309	1317.5552
within group	1	190897.8741	190897.8741	147.1508	< 0.0001
within group:sex	1	2149.2796	2149.2796	1.6567	0.1985
within group:strain	38	303674.5733	7991.4361	6.1601	< 0.0001
within group:sex:strain	38	92743.0479	2440.6065	1.8813	0.0014
within Residuals	589	764106.2251	1297.2941

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Naggert1	14302	metabolic panel	high-fat diet	glucose (plasma GLU, 4h fast) [mg/dL] baseline GLU	inbred w/CC7	43	both	7-9wks
Naggert1	14303	metabolic panel	high-fat diet	glucose (plasma GLU, 4h fast) [mg/dL] after 17wks on diet GLU_fat17	inbred w/CC7	42	both	7-9wks
Naggert1	14304	metabolic panel	high-fat diet	glucose (plasma GLU, 4h fast) [mg/dL] fold change GLU_foldchg_fat17	inbred w/CC7	42	both	7-9wks	(supplemental / summary measure)