MPD: Project measures / variables set: Nadeau3 HOMA

Project measures / variables set: Nadeau3 HOMA_IR

ID, description, units	MPD:114352 HOMA_IR homeostasis model assessment insulin resistance (overnight fast) after 16 wks on diet [] high-fat high-sucrose diet study
Measures	• chow • HFHS
Data set, strains	Nadeau3 inbred 2 strains sex: m age: 21wks
Procedure	hormone quantification
Comparison	control group vs. treated group
Ontology mappings	VT:0001560 blood insulin amount MA:0002501 plasma MP:0001560 abnormal circulating insulin level MP:0005331 insulin resistance

Values Means Δ Means Z-scores

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Nadeau3 - homeostasis model assessment insulin resistance (overnight fast) after 16 wks on diet

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	3551.1337	3551.1337	24.3889	< 0.0001
strain	1	4181.2579	4181.2579	28.7165	< 0.0001
group:strain	1	2686.6628	2686.6628	18.4518	< 0.0001
Residuals	63	9173.0821	145.6045

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Nadeau3	114352	hormone quantification	high-fat high-sucrose diet	homeostasis model assessment insulin resistance (overnight fast) after 16 wks on diet [] chow HOMA_IR_chow	inbred	2	m	21wks
Nadeau3	114353	hormone quantification	high-fat high-sucrose diet	homeostasis model assessment insulin resistance (overnight fast) after 16 wks on diet [] HFHS HOMA_IR_HFHS	inbred	2	m	21wks