MPD: Phenotype measures mapped to MP:0005388, respiratory system phenotype

Phenotype measures associated with ontology term
MP:0005388 'respiratory system phenotype'

All measures in this list are mapped to the ontology descendants of MP:0005388. None are mapped to MP:0005388 directly.

MP:0001942 abnormal lung volume
MP:0001943 abnormal respiration
MP:0001951 abnormal breathing pattern
MP:0001954 respiratory distress
MP:0002270 abnormal pulmonary alveolus morphology
MP:0002304 abnormal total lung capacity
MP:0002306 abnormal functional residual capacity
MP:0002308 abnormal residual volume
MP:0002309 abnormal vital capacity
MP:0002311 abnormal inspiratory capacity
MP:0002313 abnormal tidal volume
MP:0002325 abnormal pulmonary diffusing capacity
MP:0002327 abnormal respiratory function
MP:0002328 abnormal airway resistance
MP:0002333 abnormal lung compliance
MP:0002334 abnormal airway responsiveness
MP:0002336 abnormal pulmonary gas exchange
MP:0005629 abnormal lung weight
MP:0006050 pulmonary fibrosis
MP:0011043 abnormal lung elastance

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)	Year
Ackerman1:1	Ackerman1	ventilator	methacholine	individual pulmonary resistance values, a percentage of baseline for the 100 µg/kg dose [%] RL100 15601	QTL population		f	7-8wks	N=372	2005

Ackerman1:2	Ackerman1	ventilator	methacholine	individual pulmonary resistance, a percentage of baseline for the 330 µg/kg dose [%] RL330 15602	QTL population		f	7-8wks	N=372	2005

Ackerman1:3	Ackerman1	ventilator	methacholine	individual pulmonary resistance, a percentage of baseline for the 1000 µg/kg dose [%] RL1000 15603	QTL population		f	7-8wks	N=372	2005

Ackerman1:4	Ackerman1	ventilator	methacholine	individual pulmonary resistance, a percentage of baseline for the 3300 µg/kg dose [%] RL3300 15604	QTL population		f	7-8wks	N=372	2005

Ackerman1:5	Ackerman1	ventilator	methacholine	effective doses of methacholine required for a 1.50-fold increase in R_L), log transformed [log(n)] logED150 15605	QTL population		f	7-8wks	N=372	2005

Auwerx1:55	Auwerx1	monitoring system	high-fat diet	respiratory exchange rate (VCO2:VO2), 24h test, during day [ratio] rer_day 111234 CD HFD	BXD w/par	53	m	16wks	N=4	2016

Auwerx1:57	Auwerx1	monitoring system	high-fat diet	respiratory exchange rate (VCO2:VO2), 24h test, during night [ratio] rer_night 111236 CD HFD	BXD w/par	53	m	16wks	N=4	2016

Auwerx1:131	Auwerx1	monitoring system	high-fat diet	basal respiratory exchange ratio (RER), prior to first treadmill training (VCO2:VO2), 15 min time period, last 2 min analyzed [ratio] rer_basal 111310 CD HFD	BXD w/par	57	m	23wks	N=4	2016

Auwerx1:139	Auwerx1	monitoring system	high-fat diet	maximum respiratory exchange ratio (RER), first treadmill training (VCO2:VO2) [ratio] rer_max_treadmill1 111318 CD HFD	BXD w/par	57	m	23wks	N=4	2016

Auwerx1:157	Auwerx1	monitoring system	high-fat diet	basal respiratory exchange ratio (RER), second treadmill training (VCO2:VO2) [ratio] rer_basal_treadmill2 111336 CD HFD	BXD w/par	57	m	25wks	N=4	2016

Auwerx1:159	Auwerx1	monitoring system	high-fat diet	maximum respiratory exchange ratio (RER), second treadmill test (VCO2:VO2) [ratio] rer_max_treadmill2 111338 CD HFD	BXD w/par	57	m	25wks	N=4	2016

Auwerx2:49	Auwerx2	monitoring system	(none)	respiratory exchange rate (VCO2:VO2), 24h test, day time average [ratio] rer_day 114577 CD HFD	inbred w/CC8	9	both	14wks	N=4	2021

Auwerx2:51	Auwerx2	monitoring system	(none)	respiratory exchange rate (VCO2:VO2), 24h test, night time average [ratio] rer_night 114579 CD HFD	inbred w/CC8	9	both	14wks	N=4	2021

Auwerx2:109	Auwerx2	monitoring system	(none)	basal respiratory exchange ratio (RER), prior to treadmill test (VCO2:VO2), 15 min time period, last 2 min analyzed [ratio] rer_basal 114637 CD HFD	inbred w/CC8	9	both	19wks	N=4	2021

Auwerx2:113	Auwerx2	monitoring system	(none)	maximum oxygen consumption, treadmill test [ratio] vo2_max_treadmill 114641 CD HFD	inbred w/CC8	9	both	19wks	N=4	2021

Auwerx2:117	Auwerx2	monitoring system	(none)	maximum respiratory exchange ratio (RER), treadmill test (VCO2:VO2) [ratio] rer_max_treadmill 114645 CD HFD	inbred w/CC8	9	both	19wks	N=4	2021

Bennett4:141	Bennett4	monitoring system	various diets 2	respiratory exchange ratio (VCO2/O2), day [ratio] RER_day 114835 diet: HP group HFHS group	CC	22	f	17-20wks	N=4	2021

Bennett4:143	Bennett4	monitoring system	various diets 2	respiratory exchange ratio (VCO2/O2), night [ratio] RER_night 114837 diet: HP group HFHS group	CC	22	f	17-20wks	N=4	2021

Bennett4:145	Bennett4	monitoring system	various diets 2	respiratory exchange ratio (VCO2/O2), average for day and night [ratio] RER_ave 114839 diet: HP group HFHS group	CC	22	f	17-20wks	N=4	2021

Berndt1:1	Berndt1	ventilator	(none)	airway resistance (naive, untreated, H₂O pressure) [cm/mL/s] airway_res 34201	inbred	37	both	9-12wks	N=9	2010

Berndt1:10	Berndt1	ventilator	methacholine	airway resistance (H₂O pressure) [cm/mL/s] airway_res_series 34210 baseline MCh challenge (mg/mL): 1 3 10 30	inbred	37	both	9-12wks	N=8	2010

Berndt1:21	Berndt1	ventilator	methacholine	airway resistance (as % of baseline, H₂O pressure) [%] pct_res 34221 MCh challenge (mg/mL): 1 3 10 30	inbred	37	both	9-12wks	N=8	2010

Berndt2:1	Berndt2	plethysmography	methacholine	minute ventilation [mL/min] min_vent 35101 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:8	Berndt2	plethysmography	methacholine	breath frequency [n/min] breath_freq 35108 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:14	Berndt2	plethysmography	methacholine	inspiratory phase [s] inspiratory 35114 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:21	Berndt2	plethysmography	methacholine	expiratory phase [s] expiratory 35121 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:28	Berndt2	plethysmography	methacholine	respiratory cycle [s] tot_respi 35128 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:34	Berndt2	plethysmography	methacholine	duty cycle [ratio] duty_cycle 35134 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:41	Berndt2	plethysmography	methacholine	inspiratory flow rate [mL/kg/s] insp_flow 35141 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:48	Berndt2	plethysmography	methacholine	expiratory flow rate [mL/kg/s] exp_flow 35148 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:54	Berndt2	plethysmography	methacholine	respiratory flow rate [mL/kg/s] resp_flow 35154 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:61	Berndt2	plethysmography	methacholine	enhanced pause penh 35161 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:68	Berndt2	plethysmography	methacholine	tidal volume [mL] tidal_vol 35168 saline 5 MCh 10 MCh 20 MCh response index	inbred	29	both	9-12wks	N=8	2010

Berndt2:81	Berndt2	ventilator	methacholine	airway resistance (H₂0 pressure) [cm/mL/s] airway_res 35181 saline 1 MCh 3 MCh 10 MCh 30 MCh response index	inbred	29	both	9-12wks	N=9	2010

Berndt2:91	Berndt2	ventilator	methacholine	lung tissue dynamic elastance (H₂0 pressure) [cm/mL] airway_elas 35191 saline 1 MCh 3 MCh 10 MCh 30 MCh response index	inbred	29	both	9-12wks	N=9	2010

Bubier3:1	Bubier3	monitoring system	morphine	minimum respiratory depression (breath rate, percentage of baseline), post injection [%] min_depression 64901	inbred w/CC8	8	both	8-24wks	N=6	2019

GMC09:33	GMC09	monitoring system	(none)	mean respiratory exchange rate, 21 h test, 15 min bins [ratio] RER_mean 55833	inbred w/CC8	8	both	12-13wks	N=17	2018

GMC12:11	GMC12	echocardiography	(none)	respiration rate [n/min] resp_rate 56111	inbred w/CC8	8	both	14-15wks	N=15	2018

GMC19:11	GMC19	ventilator	(none)	residual volume (RV) in the lungs after a maximal exhalation [mL] residual_vol 56811	inbred w/CC8	7	f	21-22wks	N=3	2018

GMC19:12	GMC19	ventilator	(none)	expiratory reserve volume (ERV), FVC minus IC [mL] expiratory_vol 56812	inbred w/CC8	8	f	21-22wks	N=3	2018

GMC19:13	GMC19	ventilator	(none)	forced expiratory volume expired in first 100 ms of fast expiration (FEV100) [mL] forced_expiratory_vol 56813	inbred w/CC8	8	f	21-22wks	N=3	2018

GMC19:14	GMC19	ventilator	(none)	tidal volume (TV) of air into or out of lungs during quiet breathing [mL] tidal_vol 56814	inbred w/CC8	8	f	21-22wks	N=4	2018

GMC19:21	GMC19	ventilator	(none)	total lung capacity (TLC), volume in the lungs at maximal inflation, sum of VC and RV [mL] lung_capacity 56821	inbred w/CC8	7	f	21-22wks	N=3	2018

GMC19:22	GMC19	ventilator	(none)	vital capacity (VC), volume of air breathed out after deepest inhalation [mL] vital_capacity 56822	inbred w/CC8	8	f	21-22wks	N=3	2018

GMC19:23	GMC19	ventilator	(none)	forced vital capacity (FVC), volume expired during fast expiration [mL] forced_capacity 56823	inbred w/CC8	8	f	21-22wks	N=3	2018

GMC19:24	GMC19	ventilator	(none)	inspiratory capacity (IC), volume inspired during slow inspiration [mL] inspiratory_capacity 56824	inbred w/CC8	8	f	21-22wks	N=3	2018

GMC19:25	GMC19	ventilator	(none)	functional residual capacity (FRC), volume in lungs at end-expiratory position [mL] residual_capacity 56825	inbred w/CC8	8	f	21-22wks	N=3	2018

GMC19:31	GMC19	ventilator	(none)	lung compliance (chord compliance) (H₂O pressure) [mL/cm] chord_compliance 56831	inbred w/CC8	8	f	21-22wks	N=3	2018

GMC19:32	GMC19	ventilator	(none)	dynamic compliance (C) of respiratory system with breathing rate of 130/min (H₂O pressure) [mL/cm] dynamic_compliance 56832	inbred w/CC8	8	f	21-22wks	N=4	2018

GMC19:41	GMC19	ventilator	(none)	respiratory system resistance (H₂O pressure) [cm/mL/s] resistance 56841	inbred w/CC8	8	f	21-22wks	N=4	2018

GMC19:42	GMC19	ventilator	(none)	peak expiratory flow (PEF) [mL/s] peak_flow 56842	inbred w/CC8	8	f	21-22wks	N=3	2018

Haston1:1	Haston1	health assessment	radiation	number of days in the absence of respiratory distress [d] survival 48801	inbred	26	both	15-36wks	N=7	2012

Haston1:2	Haston1	histopathology	radiation	percentage of lung surface covered by fibrotic scar [%] fibrosis 48802	inbred	26	both	15-36wks	N=6	2012

Mathes1:9	Mathes1	monitoring system	(none)	nocturnal respiratory exchange ratio (RER) prior to wheel running (VCO2:VO2) [ratio] RER_pre 45209	CC pre w/par	138	m	10-12wks	N=1	2011

McMullan7:27	McMullan7	monitoring system	(none)	mean respiratory exchange rate at start of experiment, during day [ratio] RER_d_start 61627 no exercise group moderate intensity group high intensity group	CC	4	both	8-10wks	N=8	2018

McMullan7:31	McMullan7	monitoring system	exercise	mean respiratory exchange rate after 4 wks of treatment, during day [ratio] RER_d_end 61631 no exercise group moderate intensity group high intensity group	CC	4	both	8-10wks	N=8	2018

McMullan7:34	McMullan7	monitoring system	(none)	mean respiratory exchange rate at start of experiment, during night [ratio] RER_n_start 61634 no exercise group moderate intensity group high intensity group	CC	4	both	8-10wks	N=8	2018

McMullan7:37	McMullan7	monitoring system	exercise	mean respiratory exchange rate after 4 wks of treatment, during night [ratio] RER_n_end 61637 no exercise group moderate intensity group high intensity group	CC	4	both	8-10wks	N=8	2018

Schughart5:81	Schughart5	organ weights	influenza A (H3N2) virus	lung weight, control group, day 3 [g] lungwt_ctrl_d3 58881	inbred w/CC8	8	f	10wks	N=3	2016

Schughart5:83	Schughart5	organ weights	influenza A (H3N2) virus	lung weight, treated group [g] lungwt_trt 58883 days post-infection: 3 5 8 18 30	inbred w/CC8	8	f	10wks	N=4	2016

Schughart5:91	Schughart5	organ weights	influenza A (H3N2) virus	relative lung weight, control group, day 3 [%] lungwtadj_ctrl_d3 58891	inbred w/CC8	8	f	10wks	N=3	2016

Schughart5:93	Schughart5	organ weights	influenza A (H3N2) virus	relative lung weight, treated group [%] lungwtadj_trt 58893 days post-infection: 3 5 8 18 30	inbred w/CC8	8	f	10wks	N=4	2016

Schulz1:6	Schulz1	ventilator	(none)	inspiratory capacity (+ 25 cm H₂O) [µL] IC 1606	inbred	7	both	12-14wks	N=15	2000

Schulz1:7	Schulz1	ventilator	(none)	functional residual capacity [µL] FRC 1607	inbred	7	both	12-14wks	N=15	2000

Schulz1:8	Schulz1	ventilator	(none)	total lung capacity [µL] TLC 1608	inbred	7	both	12-14wks	N=15	2000

Schulz1:9	Schulz1	ventilator	(none)	vital capacity [µL] VC 1609	inbred	7	both	12-14wks	N=15	2000

Schulz1:10	Schulz1	ventilator	(none)	dynamic compliance of respiratory system with breathing rate of 130 per min (H₂O pressure) [µL/cm] Cdyn130 1610	inbred	7	both	12-14wks	N=15	2000

Schulz1:11	Schulz1	ventilator	(none)	static compliance of respiratory system (H₂O pressure) [µL/cm] CRS 1611	inbred	7	both	12-14wks	N=15	2000

Schulz1:12	Schulz1	ventilator	(none)	static compliance of lung (H₂O pressure) [µL/cm] CL 1612	inbred	7	both	12-14wks	N=14	2000

Schulz1:13	Schulz1	ventilator	(none)	respiratory system resistance with breathing rate of 130 per min (H₂O pressure) [cm/mL/s] R 1613	inbred	7	both	12-14wks	N=15	2000

Schulz1:14	Schulz1	ventilator	(none)	specific respiratory system resistance with breathing rate of 130 per min related to total lung capacity (H₂O pressure) [cm⋅s] sR 1614	inbred	7	both	12-14wks	N=15	2000

Schulz1:16	Schulz1	ventilator	(none)	intrapulmonary gas mixing: slope of phase III (Hg pressure) [mm/mL] slope 1616	inbred	7	both	12-14wks	N=15	2000

Schulz1:17	Schulz1	ventilator	(none)	alveolar volume [µL] VA 1617	inbred	7	both	12-14wks	N=14	2000

Schulz1:18	Schulz1	ventilator	(none)	diffusing capacity: carbon monoxide [µmol/min/hPa] D_CO 1618	inbred	7	both	12-14wks	N=14	2000

Schulz1:19	Schulz1	ventilator	(none)	specific diffusing capacity: carbon monoxide to alveolar volume [µmol/min/hPa/mL] sD_CO 1619	inbred	7	both	12-14wks	N=14	2000

Schulz1:20	Schulz1	ventilator	(none)	functional residual capacity to total lung capacity [µL/µL] ratio_FRC_TLC 1620	inbred	7	both	12-14wks	N=15	2000

Schulz1:22	Schulz1	ventilator	(none)	total lung capacity to body weight [µL/g] ratio_TLC_bw 1622	inbred	7	both	12-14wks	N=15	2000

Schulz1:23	Schulz1	ventilator	(none)	vital capacity to body weight [L/g] ratio_VC_bw 1623	inbred	7	both	12-14wks	N=15	2000

Schulz1:24	Schulz1	ventilator	(none)	functional residual capacity to body weight [µL/g] ratio_FRC_bw 1624	inbred	7	both	12-14wks	N=14	2000

Schulz1:26	Schulz1	ventilator	(none)	static compliance of lung related to total lung capacity (H₂O pressure) [1/cm] ratio_CL_TLC 1626	inbred	7	both	12-14wks	N=14	2000

Schulz1:27	Schulz1	ventilator	(none)	dynamic compliance of respiratory system (breathing rate 130/min) related to total lung capacity (H₂O pressure) [1/cm] ratio_Cdyn130_TLC 1627	inbred	7	both	12-14wks	N=15	2000

Schulz1:30	Schulz1	ventilator	(none)	Fowler dead space volume to total lung capacity [µL/µL] ratio_VDF_TLC 1630	inbred	7	both	12-14wks	N=15	2000

Schulz1:31	Schulz1	ventilator	(none)	Fowler dead space volume to body weight [µL/g] ratio_VDF_bw 1631	inbred	7	both	12-14wks	N=14	2000

Schulz1:32	Schulz1	ventilator	(none)	Fowler dead space volume [µL] VDF 1632	inbred	7	both	12-14wks	N=15	2000

Seburn1:14	Seburn1	monitoring system	(none)	respiratory exchange ratio, 3 day test [ratio] RER 9214 daily light dark	inbred	16	both	7-9wks	N=8	2001

Zimmermann1:15	Zimmermann1	monitoring system	(none)	respiratory exchange ratio (VCO2:VO2), second day [ratio] rer 112178 during light during dark	inbred	30	both	7-15wks	N=11	2020

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