McMullan7: Energy balance traits after forced exercise in 4 Collaborative Cross strains of mice (2018)

McMullan RC, Ferris MT, Bell TA, Menachery VD, Baric RS, Hua K, Pomp D, Smith-Ryan AE, de Villena FP. CC002/Unc females are mouse models of exercise-induced paradoxical fat response. Physiol Rep. 2018 Jun;6(12):e13716. doi: 10.14814/phy2.13716.   PubMed 29924460  


         
Four strains were selected based on the following criteria: 1) ability to run on treadmills, 2) fat response type to voluntary exercise, 3) endurance ability (MPD datasets: McMullan1, McMullan2, McMullan3; McMullan4; all data was collected in older females). Selected strains were: CC002/Unc adverse fat responder, low endurance; CC027/GeniUnc adverse fat responder, high endurance; CC013/GeniUnc standard fat responder, low endurance; and CC037/TauUnc standard fat responder, high endurance. Energy balance parameters were assessed before and after 4 wks of forced exercise on a treadmill.

Experimental groups in this study:
• None     • None     • None    

Procedures conducted:
• monitoring system  Locomotor activity, respiratory activity, body heat production, during 4 weeks of treadmill-based exercise training. 3 intensity cohorts.
• intake monitoring  Food and water intake, during 4 weeks of treadmill-based exercise training. 3 intensity cohorts.

McMullan7 downloads
• Download McMullan7 project data set     animal data, as uploaded
• Download McMullan7 animal data matrix     with factor-related expansion applied as necessary
• Download McMullan7 strain means, SD, N, etc.     one row per strain/sex/measure
Investigators Rachel C McMullan       University of North Carolina,  Chapel Hill, NC
Fernando Pardo-Manuel de Villena       University of North Carolina,  Chapel Hill, NC
Participants Ferris MT, Bell TA, Menachery VD, Baric RS, Hua K, Pomp D, Smith-Ryan AE
ContactFernando Pardo-Manuel de Villena     fernando@med.unc.edu     Lab web site
Part of a series: • McMullan6   see McMullan6
• McMullan7   (this project) McMullan7
AcknowledgementsFunding provided by NIH DK056350, AI100625, AI109761, AG049092, MH100241, DK05350, Al100625
Project type Phenotype strain survey data set
MPD identifiersMcMullan7     MPD:616
Data changelog No updates/corrections.       Initial release date: 07/2018.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
Mice: CC   4 strains   ♀♂   age 8-10wks   3 experimental groups

Select table page: First Prev 1 - 10 / 28 (28) Next Last
Sort/
Pick
Data set
Procedure / Protocol
Treatment
Phenotype Measure / Variable (click to view)
Panel
No. of Strains
Sex
Age
Sample Size (Avg)
    McMullan7 monitoring system (none) mean oxygen consumption at start of experiment, during day   [mL/h]  VO2_d_start   61601     no exercise group    moderate intensity group    high intensity group CC 4 both 8-10wks N=8
    McMullan7 monitoring system exercise mean oxygen consumption after 4 wks of treatment, during day   [mL/h]  VO2_d_end   61604     no exercise group    moderate intensity group    high intensity group CC 4 both 8-10wks N=8
    McMullan7 monitoring system (none) mean oxygen consumption at start of experiment, during night   [mL/h]  VO2_n_start   61607     no exercise group    moderate intensity group    high intensity group CC 4 both 8-10wks N=8
    McMullan7 monitoring system exercise mean oxygen consumption after 4 wks of treatment, during night   [mL/h]  VO2_n_end   61611     no exercise group    moderate intensity group    high intensity group CC 4 both 8-10wks N=8
    McMullan7 monitoring system (none) mean carbon dioxide production at start of experiment, during day   [mL/h]  VCO2_d_start   61614     no exercise group    moderate intensity group    high intensity group CC 4 both 8-10wks N=8
    McMullan7 monitoring system exercise mean carbon dioxide production after 4 wks of treatment, during day   [mL/h]  VCO2_d_end   61617     no exercise group    moderate intensity group    high intensity group CC 4 both 8-10wks N=8
    McMullan7 monitoring system (none) mean carbon dioxide production at start of experiment, during night   [mL/h]  VCO2_n_start   61621     no exercise group    moderate intensity group    high intensity group CC 4 both 8-10wks N=8
    McMullan7 monitoring system exercise mean carbon dioxide production after 4 wks of treatment, during night   [mL/h]  VCO2_n_end   61624     no exercise group    moderate intensity group    high intensity group CC 4 both 8-10wks N=8
    McMullan7 monitoring system (none) mean respiratory exchange rate at start of experiment, during day   [ratio]  RER_d_start   61627     no exercise group    moderate intensity group    high intensity group CC 4 both 8-10wks N=8
    McMullan7 monitoring system exercise mean respiratory exchange rate after 4 wks of treatment, during day   [ratio]  RER_d_end   61631     no exercise group    moderate intensity group    high intensity group CC 4 both 8-10wks N=8
    All boxes             To see more rows use the paging control at top.


  •   Or, add these measures to your collection.
       
  •     no folder
  •     put them in new folder