GMC09: Energy metabolism evaluated through indirect calorimetry in 8 inbred founder strains of the Collaborative Cross (2020)

German Mouse Clinic and Department of Infection Genetics, HZI   GMC Management Team   With: Hrabě de Angelis M, Fuchs H, Gailus-Durner V, Rozman J, Klingenspor M, Lengger C, Kollmus H, Schughart K

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GMC09 downloads
• Download GMC09 project data set     one row per animal, one column per trait
• Download GMC09 strain means, SD, N, etc.     one row per strain/sex/measure
• GMC09 supplementary data
Institutional authorship German Mouse Clinic and Department of Infection Genetics, HZI     Lab web site
Investigators GMC Management Team       German Mouse Clinic,  Neuherberg GERMANY
Participants Hrabě de Angelis M, Fuchs H, Gailus-Durner V, Rozman J, Klingenspor M, Lengger C, Kollmus H, Schughart K
ContactGMC Management Team     coregmc@helmholtz-muenchen.de     Lab web site
Affiliated CenterGerman Mouse Clinic (GMC)
AcknowledgementsFunding provided by German Ministry of Education and Research (Infrafrontier Grant 01KX1012) to GMC and by intramural grants from the Helmholtz Association (Program Infection and Immunity) to KS
Project type Phenotype strain survey data set
MPD identifiersGMC09     MPD:558
Data changelog No updates/corrections.       Initial release date: 02/2020.
Formatted citation
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Energy expenditure is evaluated through indirect calorimetry by measuring oxygen consumption with an open flow respirometric system. Sensors measure the difference in carbon dioxide and oxygen concentrations in air volumes flowing through animal cages. The respiratory exchange ratio (RER) and heat production are calculated. An activity and food and water intake monitoring system are also integrated into the set up.

Summary of procedures that were conducted
• monitoring system Locomotor activity and energy metabolism. 21h test.
• intake monitoring Food, water intake. 21h test.
Mice: inbred w/CC8   8 strains   ♀♂   age 12-13wks   5 experimental groups