Mathes1: Energy balance traits in 8 inbred founder strains and 170+ emerging lines (pre-CC) of the Collaborative Cross (2011)

Mathes WF, Aylor DL, Miller DR, Churchill GA, Chesler EJ, de Villena FP, Threadgill DW, Pomp D. Architecture of energy balance traits in emerging lines of the Collaborative Cross. Am J Physiol Endocrinol Metab. 2011 Jun;300(6):E1124-34. Epub 2011 Mar 22.   PubMed 21427413     FullText


       
Mathes1 downloads
• Download Mathes1 strain means, SD, N, etc.     one row per strain/sex/measure
Participants Wendy F Mathes       University of North Carolina Chapel Hill, NC
With: Aylor DL, Miller DR, Churchill GA, Chesler EJ, de Villena FP, Threadgill DW, Pomp D
ContactWendy F Mathes     wfmathes@med.unc.edu
AcknowledgementsFunding provided by NIH DK076050, DK056350, CA105417, CA134240, GM076468, GM090667, MH090338, MH076694, HD01441; the Ellison Medical Foundation AG-IA-0202-05; Lineberger Comprehensive Cancer Center, University Cancer Research Fund (North Carolina), US Department of Energy
Project type Phenotype strain survey data set
MPD identifiersMathes1     MPD:452
Data changelog 2 updates/corrections.       Initial release date: 02/2013.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
An assessment of emerging CC lines. Generations range from G2:F5 to G2:F12. Data for the 8 founder strains are also present.

Summary of procedures that were conducted
• body weight Baseline vs. after exercise (access to running wheel).
• MRI Body composition (percent fat). Baseline vs. after exercise (access to running wheel).
• intake monitoring Caloric intake. Baseline vs. after exercise (access to running wheel). Metabolism, food intake.
• monitoring system Respiratory exchange ratio. Baseline (before access to running wheel).
• running wheel monitoring Distance, speed at days 1, 6, and 12.
Mice: CC pre w/par   184 strains   ♂   age 10-12wks   1 cohort

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Mathes1 45201 body weight exercise body weight   [g]     before exercise    after exercise    difference CC pre w/par 184 m 10-12wks N=1
    Mathes1 45204 MRI exercise percent fat, whole body with head   [%]     before exercise    after exercise    difference CC pre w/par 184 m 10-12wks N=1
    Mathes1 45207 intake monitoring exercise caloric intake   [kcal/d]     before exercise    during exercise CC pre w/par 182 m 10-12wks N=1
    Mathes1 45209 monitoring system (none) nocturnal respiratory exchange ratio (RER) prior to wheel running (VCO2:VO2)   [ratio]  RER_pre CC pre w/par 138 m 10-12wks N=1
    Mathes1 45210 running wheel monitoring (none) distance traveled on wheel   [m/d]     day 1    day 6    day 12 CC pre w/par 184 m 10-12wks N=1
    Mathes1 45213 running wheel monitoring (none) speed on wheel   [m/min]     day 1    day 6    day 12 CC pre w/par 184 m 10-12wks N=1
    All boxes