Zimmermann1: Voluntary activity and energy expenditure in light and dark periods in 30 inbred strains of mice (2020)

König C, Plank AC, Kapp A, Timotius IK, von Hörsten S, Zimmermann K. Thirty Mouse Strain Survey of Voluntary Physical Activity and Energy Expenditure: Influence of Strain, Sex and Day-Night Variation. Front Neurosci. 2020;14:531. doi: 10.3389/fnins.2020.00531. Epub 2020 Jul 7.   PubMed 32733181     FullText


         
Zimmermann1 downloads
• Download Zimmermann1 project data set     animal data, as uploaded
• Download Zimmermann1 animal data matrix     with factor-related expansion applied as necessary
• Download Zimmermann1 strain means, SD, N, etc.     one row per strain/sex/measure
Investigators Christine König       Friedrich-Alexander-Universität Erlangen-Nürnberg,  Erlangen, Bavaria Germany
Katharina Zimmermann       Friedrich-Alexander-Universität Erlangen-Nürnberg,  Erlangen, Bavaria Germany
Participants Plank AC, Kapp A, Timotius IK, von Hörsten S
ContactKatharina Zimmermann     katharina.zimmermann@fau.de
Funding Provided ByDAAD 57129429, EU Joint Programme-Neurodegenerative Disease Research project CrossSeeds 01ED1501C, DFG ZI 1172/3-1, ZI 1172/3-2, ZI 1172/4-1, the Interdisciplinary Center for Clinical Research Erlangen
Project type Phenotype strain survey data set
MPD identifiersZimmermann1     MPD:1036
Data changelog No updates/corrections.       Initial release date: 11/2020.
Formatted citation
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Voluntary physical activity and energy expenditure on both sexes of 30 inbred mouse strains were ascertained in an automated phenotyping home cage system during a 48h test (data from the second day was used). The influence of strain, sex and dark and light periods were investigated on 7-15 week old mice. Indirect calorimetry and activity parameters, VO2 and VCO2 are used to extract respiratory exchange ratio (RER) in both male and female mice during one photophase and the subsequent scotophase.

Experimental groups in this study:
• Baseline    

Procedures conducted:
• body weight 
• intake monitoring  Food and water intake; 2-day test, second day data analyzed during 12:12h light and dark periods.
• monitoring system  Voluntary activity and energy expenditure. 2-day test, second day data analyzed during 12:12h light and dark periods.

Mice: inbred   30 strains   ♀♂   age 7-15 wks   1 experimental group