|
| ALT_hf serum alanine transaminase (ALT)
, high-fat only
43001
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| ALT_hfe serum alanine transaminase (ALT)
, high-fat and ethanol
43002
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| plasma_homocysteine_hf homocysteine concentration (plasma)
, high-fat only
43003
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
|
| plasma_homocysteine_hfe homocysteine concentration (plasma)
, high-fat and ethanol
43004
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
|
| BAC_hf blood alcohol concentration (BAC)
, high-fat only
43005
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| BAC_hfe blood alcohol concentration (BAC)
, high-fat and ethanol
43006
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| avg_UAC_hf urine alcohol concentration (UAC), daily average
, high-fat only
43007
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| avg_UAC_hfe urine alcohol concentration (UAC), daily average
, high-fat and ethanol
43008
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| peak_UAC_hf urine alcohol concentration (UAC), daily peak
, high-fat only
43009
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| peak_UAC_hfe urine alcohol concentration (UAC), daily peak
, high-fat and ethanol
43010
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| pctLW_BW_hf liver weight as a percent of body weight
, high-fat only
43011
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| pctLW_BW_hfe liver weight as a percent of body weight
, high-fat and ethanol
43012
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| steatosis_hf liver steatosis (0-4)
, high-fat only
43013
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| steatosis_hfe liver steatosis (0-4)
, high-fat and ethanol
43014
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| inflammation_hf liver inflammation (0-2)
, high-fat only
43015
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| inflammation_hfe liver inflammation (0-2)
, high-fat and ethanol
43016
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| necrosis_hf liver necrosis (0-2)
, high-fat only
43017
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| necrosis_hfe liver necrosis (0-2)
, high-fat and ethanol
43018
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| total_pathology_hf total liver histopathology (0-8)
, high-fat only
43019
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| total_pathology_hfe total liver histopathology (0-8)
, high-fat and ethanol
43020
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| liver_TG_hf hepatic triglycerides (TG)
, high-fat only
43021
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
|
|
|
|
|
3 |
|
|
3 |
|
3 |
3 |
3 |
|
| liver_TG_hfe hepatic triglycerides (TG)
, high-fat and ethanol
43022
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
|
|
|
|
|
3 |
|
|
3 |
|
3 |
3 |
3 |
|
| liver_GSH_hf reduced liver glutathione (GSH)
, high-fat only
43023
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| liver_GSH_hfe reduced liver glutathione (GSH)
, high-fat and ethanol
43024
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
|
| liver_GSSG_hf oxidized liver glutathione (GSSG)
, high-fat only
43025
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| liver_GSSG_hfe oxidized liver glutathione (GSSG)
, high-fat and ethanol
43026
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
|
| liver_GSHratio_hf ratio of reduced to oxidized liver glutathione
, high-fat only
43029
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| liver_GSHratio_hfe ratio of reduced to oxidized liver glutathione
, high-fat and ethanol
43030
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
|
| liver_homocysteine_hf liver homocysteine
, high-fat only
43031
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| liver_homocysteine_hfe liver homocysteine
, high-fat and ethanol
43032
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
|
| liver_SAH_hf liver S-adenosylhomocysteine (SAH)
, high-fat only
43033
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| liver_SAH_hfe liver S-adenosylhomocysteine (SAH)
, high-fat and ethanol
43034
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
|
| liver_methionine_hf liver methionine
, high-fat only
43035
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| liver_methionine_hfe liver methionine
, high-fat and ethanol
43036
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
|
| liver_SAM_hf liver S-adenosylmethionine (SAM)
, high-fat only
43037
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| liver_SAM_hfe liver S-adenosylmethionine (SAM)
, high-fat and ethanol
43038
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
|
| liver_SAM_SAH_hf ratio of liver SAM to SAH (SAM/SAH)
, high-fat only
43039
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| liver_SAM_SAH_hfe ratio of liver SAM to SAH (SAM/SAH)
, high-fat and ethanol
43040
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
|
| liver_BHMT_hfe liver BHMT, protein expression relative to high-fat-only group
43042
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
2 |
2 |
3 |
3 |
3 |
3 |
|
| liver_DDIT3_hfe liver DDIT3 (formerly CHOP), protein expression relative to high-fat-only group
43044
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
2 |
2 |
3 |
3 |
3 |
3 |
|
| liver_HSPA5_hfe liver HSPA5 (formerly GRP78), protein expression relative to high-fat-only group
43046
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
2 |
3 |
3 |
2 |
3 |
3 |
3 |
2 |
2 |
3 |
3 |
3 |
3 |
|
| liver_SREBF1_hfe liver SREBF1 (formerly NSREBP1), protein expression relative to high-fat-only group
43048
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| liver_Acox1_hfe liver Acox1, mRNA abundance relative to high-fat-only group
43050
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
|
|
|
|
|
3 |
|
|
3 |
|
3 |
3 |
3 |
|
| liver_Adipor2_hfe liver Adipor2, mRNA abundance relative to high-fat-only group
43052
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
|
|
|
|
|
3 |
|
|
3 |
|
3 |
2 |
3 |
|
| liver_Ahcy_hfe liver Ahcy, mRNA abundance relative to high-fat-only group
43054
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| liver_Cbs_hfe liver Cbs, mRNA abundance relative to high-fat-only group
43056
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| liver_Cebpa_hfe liver Cebpa, mRNA abundance relative to high-fat-only group
43058
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
3 |
3 |
3 |
3 |
|
| liver_Cth_hfe liver Cth, mRNA abundance relative to high-fat-only group
43060
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| liver_Ddit3_hfe liver Ddit3 (formerly Chop), mRNA abundance relative to high-fat-only group
43062
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| liver_Gnmt_hfe liver Gnmt, mRNA abundance relative to high-fat-only group
43064
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| liver_Mat1a_hfe liver Mat1a, mRNA abundance relative to high-fat-only group
43066
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| liver_Mthfr_hfe liver Mthfr, mRNA abundance relative to high-fat-only group
43068
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
| liver_Mtr_hfe liver Mtr, mRNA abundance relative to high-fat-only group
43070
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
2 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
2 |
3 |
|
| liver_Mttp_hfe liver Mttp, mRNA abundance relative to high-fat-only group
43072
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
|
|
|
|
|
3 |
|
|
3 |
|
3 |
3 |
3 |
|
| liver_Srebf1_hfe liver Srebf1, mRNA abundance relative to high-fat-only group
43074
|
Female |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Male |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
