Project measure / variable:   Rusyn5   total_pathology_hfe

ID, description, units MPD:43020   total_pathology_hfe   total liver histopathology (0-8)   [score]  high-fat and ethanol  
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure histopathology
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn5 - total liver histopathology (0-8) high-fat and ethanol



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means3.48   score
Median of the strain means3.25   score
SD of the strain means± 1.27
Coefficient of variation (CV)0.364
Min–max range of strain means1.50   –   6.17   score
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 62.4762 4.8059 5.0779 0.0002
Residuals 28 26.5 0.9464


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 3.0 0.866   3 0.5 0.289 2.0, 3.5 -0.38
AKR/J m 1.5 0.5   3 0.289 0.333 1.0, 2.0 -1.56
BALB/cByJ m 3.67 1.61   3 0.928 0.438 2.5, 5.5 0.15
BALB/cJ m 3.5 0.5   3 0.289 0.143 3.0, 4.0 0.02
BTBR T+ Itpr3tf/J m 2.67 1.53   3 0.882 0.573 1.0, 4.0 -0.64
C3H/HeJ m 2.67 1.44   3 0.833 0.541 1.0, 3.5 -0.64
C57BL/10J m 5.0 0.5   3 0.289 0.1 4.5, 5.5 1.2
DBA/2J m 4.17 0.577   3 0.333 0.139 3.5, 4.5 0.55
FVB/NJ m 4.33 0.764   3 0.441 0.176 3.5, 5.0 0.67
KK/HlJ m 4.5 0.0   3 0.0 0.0 4.5, 4.5 0.81
MOLF/EiJ m 2.83 1.44   3 0.833 0.509 2.0, 4.5 -0.51
NZW/LacJ m 6.17 0.764   3 0.441 0.124 5.5, 7.0 2.13
PWD/PhJ m 2.83 0.764   3 0.441 0.27 2.0, 3.5 -0.51
WSB/EiJ m 1.83 0.764   3 0.441 0.417 1.0, 2.5 -1.3


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 3.0 0.5617 4.1505 1.8495
AKR/J m 1.5 0.5617 2.6505 0.3495
BALB/cByJ m 3.6667 0.5617 4.8172 2.5161
BALB/cJ m 3.5 0.5617 4.6505 2.3495
BTBR T+ Itpr3tf/J m 2.6667 0.5617 3.8172 1.5161
C3H/HeJ m 2.6667 0.5617 3.8172 1.5161
C57BL/10J m 5.0 0.5617 6.1505 3.8495
DBA/2J m 4.1667 0.5617 5.3172 3.0161
FVB/NJ m 4.3333 0.5617 5.4839 3.1828
KK/HlJ m 4.5 0.5617 5.6505 3.3495
MOLF/EiJ m 2.8333 0.5617 3.9839 1.6828
NZW/LacJ m 6.1667 0.5617 7.3172 5.0161
PWD/PhJ m 2.8333 0.5617 3.9839 1.6828
WSB/EiJ m 1.8333 0.5617 2.9839 0.6828




  GWAS USING LINEAR MIXED MODELS