Phenotype measure:   Rusyn5   liver_Cbs_hfe

ID, description, units MPD:43056   liver_Cbs_hfe   liver Cbs, mRNA abundance relative to high-fat-only group   [%]
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure RNA expression profiling
Ontology mappings

  STRAIN COMPARISON PLOT
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Rusyn5 - liver Cbs, mRNA abundance relative to high-fat-only group



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means77.3   %
Median of the strain means78.0   %
SD of the strain means± 28.4
Coefficient of variation (CV)0.367
Min–max range of strain means27.0   –   116   %
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 31202.1948 2400.1688 8.1983 < 0.0001
Residuals 28 8197.4245 292.7652


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 78.4 24.0   3 13.9 0.307 50.6, 93.2 0.04
AKR/J m 116.0 15.6   3 8.98 0.134 98.1, 125.0 1.36
BALB/cByJ m 51.4 9.96   3 5.75 0.194 40.8, 60.6 -0.91
BALB/cJ m 101.0 9.7   3 5.6 0.0962 93.3, 112.0 0.84
BTBR T+ Itpr3tf/J m 78.1 28.2   3 16.3 0.36 57.0, 110.0 0.03
C3H/HeJ m 104.0 5.92   3 3.42 0.0572 96.8, 107.0 0.94
C57BL/10J m 57.5 17.0   3 9.83 0.296 42.9, 76.2 -0.7
DBA/2J m 56.4 8.22   3 4.75 0.146 47.3, 63.3 -0.74
FVB/NJ m 27.0 3.82   3 2.21 0.142 24.5, 31.4 -1.77
KK/HlJ m 58.1 4.11   3 2.38 0.0709 53.4, 60.9 -0.68
MOLF/EiJ m 113.0 36.4   3 21.0 0.323 89.4, 155.0 1.26
NZW/LacJ m 50.0 14.1   3 8.16 0.283 35.8, 64.1 -0.96
PWD/PhJ m 78.0 16.4   3 9.48 0.21 67.6, 96.9 0.03
WSB/EiJ m 113.0 8.53   3 4.93 0.0756 108.0, 123.0 1.26


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 78.39 9.8787 98.6256 58.1544
AKR/J m 116.09 9.8787 136.3256 95.8544
BALB/cByJ m 51.3767 9.8787 71.6122 31.1411
BALB/cJ m 100.75 9.8787 120.9856 80.5144
BTBR T+ Itpr3tf/J m 78.12 9.8787 98.3556 57.8844
C3H/HeJ m 103.5733 9.8787 123.8089 83.3378
C57BL/10J m 57.5067 9.8787 77.7422 37.2711
DBA/2J m 56.42 9.8787 76.6556 36.1844
FVB/NJ m 27.0033 9.8787 47.2389 6.7678
KK/HlJ m 58.0767 9.8787 78.3122 37.8411
MOLF/EiJ m 112.6233 9.8787 132.8589 92.3878
NZW/LacJ m 50.05 9.8787 70.2856 29.8144
PWD/PhJ m 78.0133 9.8787 98.2489 57.7778
WSB/EiJ m 112.8567 9.8787 133.0922 92.6211




  GWAS USING LINEAR MIXED MODELS