Project measure / variable:   Rusyn5   liver_methionine_hfe

ID, description, units MPD:43036   liver_methionine_hfe   liver methionine   [nmol/mg]  high-fat and ethanol  
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn5 - liver methionine high-fat and ethanol



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means0.704   nmol/mg
Median of the strain means0.712   nmol/mg
SD of the strain means± 0.204
Coefficient of variation (CV)0.290
Min–max range of strain means0.417   –   1.04   nmol/mg
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 1.605 0.1235 2.8874 0.0097
Residuals 27 1.1545 0.0428


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 1.04 0.313   3 0.181 0.302 0.69, 1.3 1.65
AKR/J m 0.87 0.14   3 0.0808 0.161 0.71, 0.97 0.81
BALB/cByJ m 0.417 0.0252   3 0.0145 0.0604 0.39, 0.44 -1.41
BALB/cJ m 0.713 0.085   3 0.0491 0.119 0.63, 0.8 0.05
BTBR T+ Itpr3tf/J m 0.563 0.0603   3 0.0348 0.107 0.5, 0.62 -0.69
C3H/HeJ m 1.01 0.236   3 0.136 0.235 0.74, 1.19 1.5
C57BL/10J m 0.753 0.129   3 0.0745 0.171 0.61, 0.86 0.24
DBA/2J m 0.71 0.23   3 0.133 0.324 0.48, 0.94 0.03
FVB/NJ m 0.95 0.521   3 0.301 0.549 0.61, 1.55 1.21
KK/HlJ m 0.52 0.0964   3 0.0557 0.185 0.41, 0.59 -0.9
MOLF/EiJ m 0.72 0.128   3 0.0737 0.177 0.58, 0.83 0.08
NZW/LacJ m 0.47 0.0721   3 0.0416 0.153 0.41, 0.55 -1.15
PWD/PhJ m 0.63 0.127   2   0.09 0.202 0.54, 0.72 -0.36
WSB/EiJ m 0.487 0.11   3 0.0633 0.225 0.4, 0.61 -1.06


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 1.0367 0.1194 1.2816 0.7917
AKR/J m 0.87 0.1194 1.115 0.625
BALB/cByJ m 0.4167 0.1194 0.6616 0.1717
BALB/cJ m 0.7133 0.1194 0.9583 0.4684
BTBR T+ Itpr3tf/J m 0.5633 0.1194 0.8083 0.3184
C3H/HeJ m 1.0067 0.1194 1.2516 0.7617
C57BL/10J m 0.7533 0.1194 0.9983 0.5084
DBA/2J m 0.71 0.1194 0.955 0.465
FVB/NJ m 0.95 0.1194 1.195 0.705
KK/HlJ m 0.52 0.1194 0.765 0.275
MOLF/EiJ m 0.72 0.1194 0.965 0.475
NZW/LacJ m 0.47 0.1194 0.715 0.225
PWD/PhJ m 0.63 0.1462 0.93 0.33
WSB/EiJ m 0.4867 0.1194 0.7316 0.2417




  GWAS USING LINEAR MIXED MODELS