Project measure / variable:   Rusyn5   ALT_hfe

ID, description, units MPD:43002   ALT_hfe   serum alanine transaminase (ALT)   [IU/L]  high-fat and ethanol  
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Rusyn5 - serum alanine transaminase (ALT) high-fat and ethanol



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means70.2   IU/L
Median of the strain means53.3   IU/L
SD of the strain means± 53.6
Coefficient of variation (CV)0.764
Min–max range of strain means13.0   –   198   IU/L
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 112094.3625 8622.6433 9.5146 < 0.0001
Residuals 28 25374.993 906.2498


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 99.3 69.8   3 40.3 0.703 24.2, 162.0 0.54
AKR/J m 13.0 3.54   3 2.04 0.272 9.74, 16.8 -1.07
BALB/cByJ m 82.1 12.0   3 6.95 0.147 73.6, 95.9 0.22
BALB/cJ m 43.7 2.46   3 1.42 0.0562 41.0, 45.7 -0.49
BTBR T+ Itpr3tf/J m 65.2 6.12   3 3.53 0.0939 58.1, 68.9 -0.09
C3H/HeJ m 67.1 48.6   3 28.1 0.725 24.8, 120.0 -0.06
C57BL/10J m 44.6 19.4   3 11.2 0.434 31.2, 66.8 -0.48
DBA/2J m 26.5 12.2   3 7.05 0.462 13.9, 38.3 -0.82
FVB/NJ m 60.4 17.3   3 9.98 0.286 41.1, 74.4 -0.18
KK/HlJ m 170.0 53.8   3 31.0 0.316 108.0, 207.0 1.86
MOLF/EiJ m 25.9 8.13   3 4.69 0.314 16.8, 32.5 -0.83
NZW/LacJ m 198.0 33.6   3 19.4 0.17 162.0, 229.0 2.38
PWD/PhJ m 40.7 17.0   3 9.82 0.418 24.4, 58.4 -0.55
WSB/EiJ m 46.2 6.51   3 3.76 0.141 40.7, 53.4 -0.45


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 99.3467 17.3805 134.9491 63.7442
AKR/J m 13.0233 17.3805 48.6258 0.0
BALB/cByJ m 82.11 17.3805 117.7124 46.5076
BALB/cJ m 43.7367 17.3805 79.3391 8.1342
BTBR T+ Itpr3tf/J m 65.1833 17.3805 100.7858 29.5809
C3H/HeJ m 67.0767 17.3805 102.6791 31.4742
C57BL/10J m 44.65 17.3805 80.2524 9.0476
DBA/2J m 26.4733 17.3805 62.0758 0.0
FVB/NJ m 60.4467 17.3805 96.0491 24.8442
KK/HlJ m 169.89 17.3805 205.4924 134.2876
MOLF/EiJ m 25.86 17.3805 61.4624 0.0
NZW/LacJ m 198.0967 17.3805 233.6991 162.4942
PWD/PhJ m 40.6567 17.3805 76.2591 5.0542
WSB/EiJ m 46.23 17.3805 81.8324 10.6276




  GWAS USING LINEAR MIXED MODELS