Project measure / variable:   Rusyn5   liver_homocysteine_hfe

ID, description, units MPD:43032   liver_homocysteine_hfe   liver homocysteine   [nmol/mg]  high-fat and ethanol  
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn5 - liver homocysteine high-fat and ethanol



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means0.277   nmol/mg
Median of the strain means0.265   nmol/mg
SD of the strain means± 0.0377
Coefficient of variation (CV)0.136
Min–max range of strain means0.237   –   0.347   nmol/mg
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 0.0553 0.0043 2.7543 0.0127
Residuals 27 0.0417 0.0015


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 0.347 0.0451   3 0.026 0.13 0.3, 0.39 1.87
AKR/J m 0.257 0.0153   3 0.00882 0.0595 0.24, 0.27 -0.52
BALB/cByJ m 0.327 0.0551   3 0.0318 0.169 0.27, 0.38 1.34
BALB/cJ m 0.237 0.0351   3 0.0203 0.148 0.2, 0.27 -1.05
BTBR T+ Itpr3tf/J m 0.34 0.0346   3 0.02 0.102 0.32, 0.38 1.68
C3H/HeJ m 0.283 0.0351   3 0.0203 0.124 0.25, 0.32 0.17
C57BL/10J m 0.243 0.0252   3 0.0145 0.103 0.22, 0.27 -0.89
DBA/2J m 0.287 0.0252   3 0.0145 0.0878 0.26, 0.31 0.28
FVB/NJ m 0.257 0.0611   3 0.0353 0.238 0.19, 0.31 -0.52
KK/HlJ m 0.287 0.0569   3 0.0328 0.198 0.24, 0.35 0.28
MOLF/EiJ m 0.26 0.0436   3 0.0252 0.168 0.23, 0.31 -0.44
NZW/LacJ m 0.237 0.0306   3 0.0176 0.129 0.21, 0.27 -1.05
PWD/PhJ m 0.27 0.0141   2   0.01 0.0524 0.26, 0.28 -0.17
WSB/EiJ m 0.24 0.0265   3 0.0153 0.11 0.21, 0.26 -0.97


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 0.3467 0.0227 0.3932 0.3001
AKR/J m 0.2567 0.0227 0.3032 0.2101
BALB/cByJ m 0.3267 0.0227 0.3732 0.2801
BALB/cJ m 0.2367 0.0227 0.2832 0.1901
BTBR T+ Itpr3tf/J m 0.34 0.0227 0.3865 0.2935
C3H/HeJ m 0.2833 0.0227 0.3299 0.2368
C57BL/10J m 0.2433 0.0227 0.2899 0.1968
DBA/2J m 0.2867 0.0227 0.3332 0.2401
FVB/NJ m 0.2567 0.0227 0.3032 0.2101
KK/HlJ m 0.2867 0.0227 0.3332 0.2401
MOLF/EiJ m 0.26 0.0227 0.3065 0.2135
NZW/LacJ m 0.2367 0.0227 0.2832 0.1901
PWD/PhJ m 0.27 0.0278 0.327 0.213
WSB/EiJ m 0.24 0.0227 0.2865 0.1935




  GWAS USING LINEAR MIXED MODELS