Project measure / variable:   Rusyn5   liver_SAH_hf

ID, description, units MPD:43033   liver_SAH_hf   liver S-adenosylhomocysteine (SAH)   [nmol/mg]  high-fat only  
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn5 - liver S-adenosylhomocysteine (SAH) high-fat only



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means0.249   nmol/mg
Median of the strain means0.257   nmol/mg
SD of the strain means± 0.0449
Coefficient of variation (CV)0.180
Min–max range of strain means0.170   –   0.310   nmol/mg
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 0.0787 0.0061 3.0924 0.006
Residuals 28 0.0548 0.002


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 0.277 0.0208   3 0.012 0.0752 0.26, 0.3 0.62
AKR/J m 0.273 0.0473   3 0.0273 0.173 0.22, 0.31 0.53
BALB/cByJ m 0.303 0.0208   3 0.012 0.0686 0.28, 0.32 1.2
BALB/cJ m 0.19 0.0265   3 0.0153 0.139 0.17, 0.22 -1.32
BTBR T+ Itpr3tf/J m 0.31 0.0529   3 0.0306 0.171 0.27, 0.37 1.35
C3H/HeJ m 0.2 0.03   3 0.0173 0.15 0.17, 0.23 -1.1
C57BL/10J m 0.267 0.0503   3 0.0291 0.189 0.22, 0.32 0.4
DBA/2J m 0.247 0.0569   3 0.0328 0.231 0.2, 0.31 -0.05
FVB/NJ m 0.223 0.0306   3 0.0176 0.137 0.19, 0.25 -0.58
KK/HlJ m 0.283 0.0404   3 0.0233 0.143 0.26, 0.33 0.75
MOLF/EiJ m 0.3 0.0794   3 0.0458 0.265 0.21, 0.36 1.13
NZW/LacJ m 0.17 0.02   3 0.0115 0.118 0.15, 0.19 -1.76
PWD/PhJ m 0.223 0.0651   3 0.0376 0.291 0.16, 0.29 -0.58
WSB/EiJ m 0.223 0.0252   3 0.0145 0.113 0.2, 0.25 -0.58


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 0.2767 0.0255 0.329 0.2243
AKR/J m 0.2733 0.0255 0.3257 0.221
BALB/cByJ m 0.3033 0.0255 0.3557 0.251
BALB/cJ m 0.19 0.0255 0.2423 0.1377
BTBR T+ Itpr3tf/J m 0.31 0.0255 0.3623 0.2577
C3H/HeJ m 0.2 0.0255 0.2523 0.1477
C57BL/10J m 0.2667 0.0255 0.319 0.2143
DBA/2J m 0.2467 0.0255 0.299 0.1943
FVB/NJ m 0.2233 0.0255 0.2757 0.171
KK/HlJ m 0.2833 0.0255 0.3357 0.231
MOLF/EiJ m 0.3 0.0255 0.3523 0.2477
NZW/LacJ m 0.17 0.0255 0.2223 0.1177
PWD/PhJ m 0.2233 0.0255 0.2757 0.171
WSB/EiJ m 0.2233 0.0255 0.2757 0.171




  GWAS USING LINEAR MIXED MODELS