Project measure / variable:   Rusyn5   liver_BHMT_hfe

ID, description, units MPD:43042   liver_BHMT_hfe   liver BHMT, protein expression relative to high-fat-only group   [%]  
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn5 - liver BHMT, protein expression relative to high-fat-only group



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means96.9   %
Median of the strain means89.2   %
SD of the strain means± 23.3
Coefficient of variation (CV)0.240
Min–max range of strain means72.2   –   166   %
Mean sample size per strain2.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 16112.5061 1239.4235 10.4474 < 0.0001
Residuals 24 2847.2266 118.6344


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 87.7 9.89   3 5.71 0.113 76.8, 96.0 -0.4
AKR/J m 96.7 15.9   2   11.3 0.165 85.5, 108.0 -0.01
BALB/cByJ m 81.3 3.6   3 2.08 0.0443 79.0, 85.4 -0.67
BALB/cJ m 89.0 1.84   3 1.07 0.0207 86.9, 90.1 -0.34
BTBR T+ Itpr3tf/J m 98.7 8.85   2   6.26 0.0897 92.5, 105.0 0.08
C3H/HeJ m 79.4 11.2   3 6.49 0.142 71.1, 92.2 -0.75
C57BL/10J m 99.5 16.5   3 9.53 0.166 80.6, 111.0 0.11
DBA/2J m 86.4 4.0   3 2.31 0.0463 82.1, 90.0 -0.45
FVB/NJ m 166.0 28.8   2   20.4 0.173 146.0, 186.0 2.97
KK/HlJ m 106.0 15.5   2   11.0 0.146 95.5, 117.0 0.39
MOLF/EiJ m 120.0 4.55   3 2.62 0.0379 115.0, 124.0 0.99
NZW/LacJ m 84.3 8.88   3 5.13 0.105 76.9, 94.2 -0.54
PWD/PhJ m 72.2 4.92   3 2.84 0.0681 68.5, 77.8 -1.06
WSB/EiJ m 89.4 8.38   3 4.84 0.0938 79.9, 95.8 -0.32


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 87.6867 6.2885 100.6654 74.7079
AKR/J m 96.735 7.7018 112.6307 80.8393
BALB/cByJ m 81.2767 6.2885 94.2554 68.2979
BALB/cJ m 89.0 6.2885 101.9788 76.0212
BTBR T+ Itpr3tf/J m 98.73 7.7018 114.6257 82.8343
C3H/HeJ m 79.37 6.2885 92.3488 66.3912
C57BL/10J m 99.4567 6.2885 112.4354 86.4779
DBA/2J m 86.41 6.2885 99.3888 73.4312
FVB/NJ m 166.07 7.7018 181.9657 150.1743
KK/HlJ m 106.5 7.7018 122.3957 90.6043
MOLF/EiJ m 119.97 6.2885 132.9488 106.9912
NZW/LacJ m 84.3033 6.2885 97.2821 71.3246
PWD/PhJ m 72.22 6.2885 85.1988 59.2412
WSB/EiJ m 89.3533 6.2885 102.3321 76.3746




  GWAS USING LINEAR MIXED MODELS