Project measure / variable:   Rusyn5   liver_Srebf1_hfe

ID, description, units MPD:43074   liver_Srebf1_hfe   liver Srebf1, mRNA abundance relative to high-fat-only group   [%]  
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure RNA expression profiling
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn5 - liver Srebf1, mRNA abundance relative to high-fat-only group



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means84.4   %
Median of the strain means77.7   %
SD of the strain means± 38.2
Coefficient of variation (CV)0.453
Min–max range of strain means37.9   –   155   %
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 56859.5234 4373.8095 20.7503 < 0.0001
Residuals 28 5901.9169 210.7827


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 68.0 27.9   3 16.1 0.41 41.7, 97.2 -0.43
AKR/J m 95.1 5.36   3 3.1 0.0564 90.3, 101.0 0.28
BALB/cByJ m 53.6 4.94   3 2.85 0.0921 48.0, 57.1 -0.81
BALB/cJ m 120.0 18.7   3 10.8 0.156 108.0, 141.0 0.93
BTBR T+ Itpr3tf/J m 95.9 8.14   3 4.7 0.0848 88.7, 105.0 0.3
C3H/HeJ m 99.7 6.56   3 3.78 0.0658 93.1, 106.0 0.4
C57BL/10J m 47.6 12.6   3 7.26 0.264 39.0, 62.0 -0.96
DBA/2J m 68.0 7.71   3 4.45 0.113 61.2, 76.4 -0.43
FVB/NJ m 46.1 1.92   3 1.11 0.0416 43.9, 47.4 -1.0
KK/HlJ m 37.9 13.2   3 7.6 0.347 27.5, 52.7 -1.22
MOLF/EiJ m 155.0 25.2   3 14.6 0.163 131.0, 181.0 1.85
NZW/LacJ m 53.6 12.1   3 6.98 0.225 39.9, 62.6 -0.81
PWD/PhJ m 87.4 4.33   3 2.5 0.0495 83.6, 92.1 0.08
WSB/EiJ m 154.0 21.6   3 12.5 0.141 131.0, 174.0 1.82


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 68.0 8.3822 85.1701 50.8299
AKR/J m 95.1 8.3822 112.2701 77.9299
BALB/cByJ m 53.6433 8.3822 70.8134 36.4732
BALB/cJ m 119.5933 8.3822 136.7634 102.4232
BTBR T+ Itpr3tf/J m 95.9467 8.3822 113.1168 78.7766
C3H/HeJ m 99.6967 8.3822 116.8668 82.5266
C57BL/10J m 47.6167 8.3822 64.7868 30.4466
DBA/2J m 68.0367 8.3822 85.2068 50.8666
FVB/NJ m 46.0867 8.3822 63.2568 28.9166
KK/HlJ m 37.9333 8.3822 55.1034 20.7632
MOLF/EiJ m 155.19 8.3822 172.3601 138.0199
NZW/LacJ m 53.6433 8.3822 70.8134 36.4732
PWD/PhJ m 87.3933 8.3822 104.5634 70.2232
WSB/EiJ m 153.71 8.3822 170.8801 136.5399




  GWAS USING LINEAR MIXED MODELS