Project measure / variable:   Rusyn5   liver_SAH_hfe

ID, description, units MPD:43034   liver_SAH_hfe   liver S-adenosylhomocysteine (SAH)   [nmol/mg]  high-fat and ethanol  
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn5 - liver S-adenosylhomocysteine (SAH) high-fat and ethanol



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means0.335   nmol/mg
Median of the strain means0.334   nmol/mg
SD of the strain means± 0.0527
Coefficient of variation (CV)0.157
Min–max range of strain means0.273   –   0.470   nmol/mg
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 0.1066 0.0082 2.0497 0.0561
Residuals 27 0.108 0.004


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 0.38 0.115   3 0.0666 0.303 0.29, 0.51 0.85
AKR/J m 0.343 0.00577   3 0.00333 0.0168 0.34, 0.35 0.15
BALB/cByJ m 0.35 0.0436   3 0.0252 0.125 0.3, 0.38 0.28
BALB/cJ m 0.31 0.02   3 0.0115 0.0645 0.29, 0.33 -0.48
BTBR T+ Itpr3tf/J m 0.47 0.03   3 0.0173 0.0638 0.44, 0.5 2.56
C3H/HeJ m 0.273 0.106   3 0.0612 0.388 0.16, 0.37 -1.18
C57BL/10J m 0.307 0.0416   3 0.024 0.136 0.26, 0.34 -0.54
DBA/2J m 0.34 0.03   3 0.0173 0.0882 0.31, 0.37 0.09
FVB/NJ m 0.367 0.116   3 0.0669 0.316 0.29, 0.5 0.6
KK/HlJ m 0.373 0.0321   3 0.0186 0.0861 0.35, 0.41 0.71
MOLF/EiJ m 0.327 0.0833   3 0.0481 0.255 0.26, 0.42 -0.16
NZW/LacJ m 0.273 0.0351   3 0.0203 0.128 0.24, 0.31 -1.18
PWD/PhJ m 0.295 0.00707   2   0.005 0.024 0.29, 0.3 -0.77
WSB/EiJ m 0.287 0.0306   3 0.0176 0.107 0.26, 0.32 -0.92


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 0.38 0.0365 0.4549 0.3051
AKR/J m 0.3433 0.0365 0.4182 0.2684
BALB/cByJ m 0.35 0.0365 0.4249 0.2751
BALB/cJ m 0.31 0.0365 0.3849 0.2351
BTBR T+ Itpr3tf/J m 0.47 0.0365 0.5449 0.3951
C3H/HeJ m 0.2733 0.0365 0.3482 0.1984
C57BL/10J m 0.3067 0.0365 0.3816 0.2318
DBA/2J m 0.34 0.0365 0.4149 0.2651
FVB/NJ m 0.3667 0.0365 0.4416 0.2918
KK/HlJ m 0.3733 0.0365 0.4482 0.2984
MOLF/EiJ m 0.3267 0.0365 0.4016 0.2518
NZW/LacJ m 0.2733 0.0365 0.3482 0.1984
PWD/PhJ m 0.295 0.0447 0.3868 0.2032
WSB/EiJ m 0.2867 0.0365 0.3616 0.2118




  GWAS USING LINEAR MIXED MODELS