Project measure / variable:   Rusyn5   liver_Mthfr_hfe

ID, description, units MPD:43068   liver_Mthfr_hfe   liver Mthfr, mRNA abundance relative to high-fat-only group   [%]  
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure RNA expression profiling
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn5 - liver Mthfr, mRNA abundance relative to high-fat-only group



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means67.2   %
Median of the strain means58.1   %
SD of the strain means± 38.7
Coefficient of variation (CV)0.577
Min–max range of strain means24.3   –   172   %
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 58500.4582 4500.0352 8.6373 < 0.0001
Residuals 28 14588.0167 521.0006


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 71.7 40.1   3 23.2 0.56 34.4, 114.0 0.12
AKR/J m 70.5 38.0   3 22.0 0.54 31.5, 108.0 0.09
BALB/cByJ m 24.3 11.6   3 6.7 0.478 10.9, 31.0 -1.11
BALB/cJ m 47.3 19.4   3 11.2 0.41 25.7, 63.3 -0.51
BTBR T+ Itpr3tf/J m 49.4 14.8   3 8.53 0.299 34.6, 64.2 -0.46
C3H/HeJ m 45.8 23.0   3 13.3 0.503 23.9, 69.8 -0.55
C57BL/10J m 79.2 18.5   3 10.7 0.233 57.9, 90.2 0.31
DBA/2J m 47.5 23.5   3 13.6 0.495 23.9, 70.9 -0.51
FVB/NJ m 33.4 14.7   3 8.48 0.44 24.5, 50.3 -0.87
KK/HlJ m 66.8 7.14   3 4.12 0.107 58.6, 71.6 -0.01
MOLF/EiJ m 172.0 37.2   3 21.5 0.216 130.0, 202.0 2.71
NZW/LacJ m 35.5 17.8   3 10.3 0.502 15.4, 49.2 -0.82
PWD/PhJ m 78.0 10.4   3 5.99 0.133 66.4, 86.4 0.28
WSB/EiJ m 119.0 0.953   3 0.55 0.00804 118.0, 120.0 1.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 71.7167 13.1783 98.7111 44.7222
AKR/J m 70.52 13.1783 97.5145 43.5255
BALB/cByJ m 24.2633 13.1783 51.2578 0.0
BALB/cJ m 47.3067 13.1783 74.3011 20.3122
BTBR T+ Itpr3tf/J m 49.4 13.1783 76.3945 22.4055
C3H/HeJ m 45.85 13.1783 72.8445 18.8555
C57BL/10J m 79.2133 13.1783 106.2078 52.2189
DBA/2J m 47.5133 13.1783 74.5078 20.5189
FVB/NJ m 33.39 13.1783 60.3845 6.3955
KK/HlJ m 66.7833 13.1783 93.7778 39.7889
MOLF/EiJ m 172.2067 13.1783 199.2011 145.2122
NZW/LacJ m 35.5333 13.1783 62.5278 8.5389
PWD/PhJ m 78.0 13.1783 104.9945 51.0055
WSB/EiJ m 118.54 13.1783 145.5345 91.5455




  GWAS USING LINEAR MIXED MODELS