Project measure / variable:   Rusyn5   necrosis_hfe

ID, description, units MPD:43018   necrosis_hfe   liver necrosis (0-2)   [score]  high-fat and ethanol  
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure histopathology
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  STRAIN COMPARISON PLOT
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Rusyn5 - liver necrosis (0-2) high-fat and ethanol



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means0.822   score
Median of the strain means0.916   score
SD of the strain means± 0.521
Coefficient of variation (CV)0.634
Min–max range of strain means0   –   1.67   score
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 10.5774 0.8136 1.2427 0.303
Residuals 28 18.3333 0.6548


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 0.333 0.289   3 0.167 0.866 -0.94
AKR/J m 0.333 0.577   3 0.333 1.73 -0.94
BALB/cByJ m 0.667 1.15   3 0.667 1.73 -0.3
BALB/cJ m 1.0 1.0   3 0.577 1.0 0.34
BTBR T+ Itpr3tf/J m 1.0 1.0   3 0.577 1.0 0.34
C3H/HeJ m 1.33 1.15   3 0.667 0.866 0.98
C57BL/10J m 1.5 0.5   3 0.289 0.333 1.0, 2.0 1.3
DBA/2J m 1.67 0.577   3 0.333 0.346 1.0, 2.0 1.63
FVB/NJ m 1.0 1.0   3 0.577 1.0 0.34
KK/HlJ m 0.0 0.0   3 0.0 0.0 -1.58
MOLF/EiJ m 0.667 1.15   3 0.667 1.73 -0.3
NZW/LacJ m 1.17 0.764   3 0.441 0.655 0.5, 2.0 0.67
PWD/PhJ m 0.833 0.764   3 0.441 0.917 0.02
WSB/EiJ m 0.0 0.0   3 0.0 0.0 -1.58


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 0.3333 0.4672 1.2903 -0.6236
AKR/J m 0.3333 0.4672 1.2903 -0.6236
BALB/cByJ m 0.6667 0.4672 1.6236 -0.2903
BALB/cJ m 1.0 0.4672 1.957 0.043
BTBR T+ Itpr3tf/J m 1.0 0.4672 1.957 0.043
C3H/HeJ m 1.3333 0.4672 2.2903 0.3764
C57BL/10J m 1.5 0.4672 2.457 0.543
DBA/2J m 1.6667 0.4672 2.6236 0.7097
FVB/NJ m 1.0 0.4672 1.957 0.043
KK/HlJ m 0.0 0.4672 0.957 -0.957
MOLF/EiJ m 0.6667 0.4672 1.6236 -0.2903
NZW/LacJ m 1.1667 0.4672 2.1236 0.2097
PWD/PhJ m 0.8333 0.4672 1.7903 -0.1236
WSB/EiJ m 0.0 0.4672 0.957 -0.957




  GWAS USING LINEAR MIXED MODELS