Project measure / variable:   Rusyn5   liver_SAM_hfe

ID, description, units MPD:43038   liver_SAM_hfe   liver S-adenosylmethionine (SAM)   [nmol/mg]  high-fat and ethanol  
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn5 - liver S-adenosylmethionine (SAM) high-fat and ethanol



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means0.562   nmol/mg
Median of the strain means0.547   nmol/mg
SD of the strain means± 0.0725
Coefficient of variation (CV)0.129
Min–max range of strain means0.470   –   0.700   nmol/mg
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 0.2035 0.0157 1.8075 0.0943
Residuals 27 0.2339 0.0087


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 0.547 0.101   3 0.0584 0.185 0.43, 0.61 -0.2
AKR/J m 0.537 0.0833   3 0.0481 0.155 0.47, 0.63 -0.34
BALB/cByJ m 0.47 0.06   3 0.0346 0.128 0.41, 0.53 -1.26
BALB/cJ m 0.483 0.0702   3 0.0406 0.145 0.41, 0.55 -1.08
BTBR T+ Itpr3tf/J m 0.53 0.06   3 0.0346 0.113 0.47, 0.59 -0.44
C3H/HeJ m 0.487 0.0666   3 0.0384 0.137 0.41, 0.53 -1.03
C57BL/10J m 0.677 0.0416   3 0.024 0.0615 0.63, 0.71 1.59
DBA/2J m 0.487 0.1   3 0.0578 0.206 0.41, 0.6 -1.03
FVB/NJ m 0.593 0.217   3 0.125 0.366 0.43, 0.84 0.43
KK/HlJ m 0.567 0.0569   3 0.0328 0.1 0.52, 0.63 0.07
MOLF/EiJ m 0.7 0.0656   3 0.0379 0.0937 0.63, 0.76 1.91
NZW/LacJ m 0.637 0.0503   3 0.0291 0.0791 0.59, 0.69 1.04
PWD/PhJ m 0.6 0.0424   2   0.03 0.0707 0.57, 0.63 0.53
WSB/EiJ m 0.547 0.115   3 0.0664 0.21 0.43, 0.66 -0.2


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 0.5467 0.0537 0.6569 0.4364
AKR/J m 0.5367 0.0537 0.6469 0.4264
BALB/cByJ m 0.47 0.0537 0.5803 0.3597
BALB/cJ m 0.4833 0.0537 0.5936 0.3731
BTBR T+ Itpr3tf/J m 0.53 0.0537 0.6403 0.4197
C3H/HeJ m 0.4867 0.0537 0.5969 0.3764
C57BL/10J m 0.6767 0.0537 0.7869 0.5664
DBA/2J m 0.4867 0.0537 0.5969 0.3764
FVB/NJ m 0.5933 0.0537 0.7036 0.4831
KK/HlJ m 0.5667 0.0537 0.6769 0.4564
MOLF/EiJ m 0.7 0.0537 0.8103 0.5897
NZW/LacJ m 0.6367 0.0537 0.7469 0.5264
PWD/PhJ m 0.6 0.0658 0.735 0.465
WSB/EiJ m 0.5467 0.0537 0.6569 0.4364




  GWAS USING LINEAR MIXED MODELS