Project measure / variable:   Rusyn5   plasma_homocysteine_hfe

ID, description, units MPD:43004   plasma_homocysteine_hfe   homocysteine concentration (plasma)   [nmol/mL]  high-fat and ethanol  
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn5 - homocysteine concentration (plasma) high-fat and ethanol



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means15.6   nmol/mL
Median of the strain means12.4   nmol/mL
SD of the strain means± 8.44
Coefficient of variation (CV)0.542
Min–max range of strain means6.97   –   35.7   nmol/mL
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 2707.8661 208.2974 4.9188 0.0002
Residuals 27 1143.3633 42.3468


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 13.3 3.67   3 2.12 0.276 9.74, 17.1 -0.27
AKR/J m 10.1 4.77   3 2.76 0.472 5.01, 14.5 -0.65
BALB/cByJ m 18.7 9.82   3 5.67 0.525 9.66, 29.1 0.37
BALB/cJ m 19.9 6.0   3 3.46 0.302 14.3, 26.2 0.51
BTBR T+ Itpr3tf/J m 10.2 1.99   3 1.15 0.195 8.58, 12.4 -0.64
C3H/HeJ m 19.9 5.66   3 3.27 0.284 13.8, 25.1 0.51
C57BL/10J m 35.7 15.8   3 9.1 0.442 17.5, 45.4 2.39
DBA/2J m 20.7 6.96   3 4.02 0.337 13.9, 27.8 0.61
FVB/NJ m 7.52 0.566   2   0.4 0.0752 7.12, 7.92 -0.95
KK/HlJ m 8.48 3.28   3 1.9 0.387 6.13, 12.2 -0.84
MOLF/EiJ m 6.97 1.11   3 0.642 0.159 6.16, 8.24 -1.02
NZW/LacJ m 26.7 6.0   3 3.46 0.225 20.2, 32.1 1.32
PWD/PhJ m 11.4 3.82   3 2.21 0.335 8.37, 15.7 -0.49
WSB/EiJ m 8.29 2.71   3 1.56 0.327 5.34, 10.7 -0.86


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 13.28 3.7571 20.9889 5.5711
AKR/J m 10.1133 3.7571 17.8222 2.4045
BALB/cByJ m 18.71 3.7571 26.4189 11.0011
BALB/cJ m 19.89 3.7571 27.5989 12.1811
BTBR T+ Itpr3tf/J m 10.2033 3.7571 17.9122 2.4945
C3H/HeJ m 19.9 3.7571 27.6089 12.1911
C57BL/10J m 35.6767 3.7571 43.3855 27.9678
DBA/2J m 20.68 3.7571 28.3889 12.9711
FVB/NJ m 7.52 4.6015 16.9614 0.0
KK/HlJ m 8.4767 3.7571 16.1855 0.7678
MOLF/EiJ m 6.9733 3.7571 14.6822 0.0
NZW/LacJ m 26.7033 3.7571 34.4122 18.9945
PWD/PhJ m 11.4233 3.7571 19.1322 3.7145
WSB/EiJ m 8.2867 3.7571 15.9955 0.5778




  GWAS USING LINEAR MIXED MODELS