Phenotype measure:   Rusyn5   liver_HSPA5_hfe

ID, description, units MPD:43046   liver_HSPA5_hfe   liver HSPA5 (formerly GRP78), protein expression relative to high-fat-only group   [%]
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Rusyn5 - liver HSPA5 (formerly GRP78), protein expression relative to high-fat-only group



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means118   %
Median of the strain means116   %
SD of the strain means± 37.1
Coefficient of variation (CV)0.313
Min–max range of strain means72.3   –   212   %
Mean sample size per strain2.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 51857.22 3989.0169 5.3616 0.0002
Residuals 24 17855.8178 743.9924


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 117.0 23.8   3 13.7 0.203 90.1, 134.0 -0.04
AKR/J m 119.0 0.502   2   0.355 0.00422 119.0, 119.0 0.02
BALB/cByJ m 126.0 8.26   3 4.77 0.0656 118.0, 135.0 0.21
BALB/cJ m 93.9 14.9   3 8.58 0.158 82.5, 111.0 -0.66
BTBR T+ Itpr3tf/J m 80.7 19.1   2   13.5 0.236 67.2, 94.2 -1.02
C3H/HeJ m 130.0 25.2   3 14.6 0.193 105.0, 155.0 0.31
C57BL/10J m 177.0 61.4   3 35.4 0.348 107.0, 222.0 1.58
DBA/2J m 118.0 2.86   3 1.65 0.0243 114.0, 120.0 -0.01
FVB/NJ m 101.0 2.47   2   1.75 0.0246 98.9, 102.0 -0.47
KK/HlJ m 115.0 44.3   2   31.3 0.386 83.4, 146.0 -0.09
MOLF/EiJ m 107.0 2.09   3 1.21 0.0195 105.0, 109.0 -0.31
NZW/LacJ m 212.0 43.0   3 24.8 0.202 181.0, 261.0 2.52
PWD/PhJ m 88.6 18.8   3 10.8 0.212 67.9, 104.0 -0.8
WSB/EiJ m 72.3 17.1   3 9.88 0.237 52.6, 84.0 -1.24


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 117.2967 15.7479 149.7988 84.7945
AKR/J m 119.035 19.2872 158.8418 79.2282
BALB/cByJ m 125.7533 15.7479 158.2555 93.2512
BALB/cJ m 93.9467 15.7479 126.4488 61.4445
BTBR T+ Itpr3tf/J m 80.695 19.2872 120.5018 40.8882
C3H/HeJ m 130.3567 15.7479 162.8588 97.8545
C57BL/10J m 176.53 15.7479 209.0321 144.0279
DBA/2J m 117.7233 15.7479 150.2255 85.2212
FVB/NJ m 100.66 19.2872 140.4668 60.8532
KK/HlJ m 114.71 19.2872 154.5168 74.9032
MOLF/EiJ m 107.34 15.7479 139.8421 74.8379
NZW/LacJ m 212.3833 15.7479 244.8855 179.8812
PWD/PhJ m 88.58 15.7479 121.0821 56.0779
WSB/EiJ m 72.2733 15.7479 104.7755 39.7712




  GWAS USING LINEAR MIXED MODELS