Phenotype measure:   Rusyn5   liver_SREBF1_hfe

ID, description, units MPD:43048   liver_SREBF1_hfe   liver SREBF1 (formerly NSREBP1), protein expression relative to high-fat-only group   [%]
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Rusyn5 - liver SREBF1 (formerly NSREBP1), protein expression relative to high-fat-only group



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means98.0   %
Median of the strain means95.2   %
SD of the strain means± 30.0
Coefficient of variation (CV)0.306
Min–max range of strain means60.1   –   156   %
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 35016.5669 2693.5821 18.1914 < 0.0001
Residuals 28 4145.9415 148.0693


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 98.3 7.17   3 4.14 0.073 90.1, 103.0 0.01
AKR/J m 146.0 5.25   3 3.03 0.036 141.0, 152.0 1.6
BALB/cByJ m 92.0 27.4   3 15.8 0.298 72.7, 123.0 -0.2
BALB/cJ m 61.8 2.39   3 1.38 0.0387 59.8, 64.4 -1.21
BTBR T+ Itpr3tf/J m 60.1 22.1   3 12.8 0.367 46.3, 85.6 -1.26
C3H/HeJ m 105.0 2.54   3 1.47 0.0241 103.0, 108.0 0.23
C57BL/10J m 86.7 7.77   3 4.48 0.0895 78.6, 94.0 -0.38
DBA/2J m 72.0 1.11   3 0.639 0.0154 70.8, 73.0 -0.87
FVB/NJ m 70.5 15.2   3 8.8 0.216 55.6, 86.1 -0.92
KK/HlJ m 100.0 15.9   3 9.17 0.159 88.1, 118.0 0.07
MOLF/EiJ m 156.0 0.979   3 0.565 0.00629 155.0, 157.0 1.93
NZW/LacJ m 79.1 7.52   3 4.34 0.095 70.4, 84.0 -0.63
PWD/PhJ m 130.0 11.2   3 6.45 0.086 123.0, 143.0 1.06
WSB/EiJ m 115.0 3.72   3 2.15 0.0323 112.0, 119.0 0.56


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 98.2867 7.0254 112.6776 83.8958
AKR/J m 145.76 7.0254 160.1509 131.3691
BALB/cByJ m 92.0467 7.0254 106.4376 77.6558
BALB/cJ m 61.7767 7.0254 76.1676 47.3858
BTBR T+ Itpr3tf/J m 60.15 7.0254 74.5409 45.7591
C3H/HeJ m 105.2033 7.0254 119.5942 90.8124
C57BL/10J m 86.7433 7.0254 101.1342 72.3524
DBA/2J m 72.04 7.0254 86.4309 57.6491
FVB/NJ m 70.4967 7.0254 84.8876 56.1058
KK/HlJ m 100.1967 7.0254 114.5876 85.8058
MOLF/EiJ m 155.6933 7.0254 170.0842 141.3024
NZW/LacJ m 79.0867 7.0254 93.4776 64.6958
PWD/PhJ m 129.9333 7.0254 144.3242 115.5424
WSB/EiJ m 115.0633 7.0254 129.4542 100.6724




  GWAS USING LINEAR MIXED MODELS