Project measure / variable:   Rusyn5   liver_DDIT3_hfe

ID, description, units MPD:43044   liver_DDIT3_hfe   liver DDIT3 (formerly CHOP), protein expression relative to high-fat-only group   [%]  
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn5 - liver DDIT3 (formerly CHOP), protein expression relative to high-fat-only group



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means147   %
Median of the strain means102   %
SD of the strain means± 117
Coefficient of variation (CV)0.793
Min–max range of strain means71.0   –   526   %
Mean sample size per strain2.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 377763.219 29058.7092 35.0201 < 0.0001
Residuals 24 19914.5368 829.7724


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 98.6 4.9   3 2.83 0.0497 93.5, 103.0 -0.42
AKR/J m 71.0 11.2   2   7.92 0.158 63.1, 79.0 -0.65
BALB/cByJ m 102.0 22.0   3 12.7 0.216 76.4, 116.0 -0.39
BALB/cJ m 146.0 66.6   3 38.5 0.456 88.7, 219.0 -0.01
BTBR T+ Itpr3tf/J m 89.4 3.59   2   2.53 0.0401 86.9, 91.9 -0.5
C3H/HeJ m 94.3 10.9   3 6.32 0.116 82.4, 104.0 -0.45
C57BL/10J m 166.0 16.5   3 9.55 0.0997 147.0, 178.0 0.16
DBA/2J m 95.6 31.9   3 18.4 0.334 74.5, 132.0 -0.44
FVB/NJ m 526.0 3.01   2   2.13 0.00573 523.0, 528.0 3.24
KK/HlJ m 137.0 6.05   2   4.27 0.0442 132.0, 141.0 -0.09
MOLF/EiJ m 101.0 12.6   3 7.28 0.125 87.3, 112.0 -0.4
NZW/LacJ m 236.0 49.8   3 28.8 0.211 179.0, 271.0 0.76
PWD/PhJ m 95.3 25.3   3 14.6 0.265 78.2, 124.0 -0.45
WSB/EiJ m 105.0 15.0   3 8.64 0.143 93.7, 122.0 -0.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 98.6067 16.631 132.9314 64.2819
AKR/J m 71.05 20.3688 113.089 29.011
BALB/cByJ m 101.7867 16.631 136.1114 67.4619
BALB/cJ m 146.0867 16.631 180.4114 111.7619
BTBR T+ Itpr3tf/J m 89.405 20.3688 131.444 47.366
C3H/HeJ m 94.28 16.631 128.6047 59.9553
C57BL/10J m 165.93 16.631 200.2547 131.6053
DBA/2J m 95.5633 16.631 129.8881 61.2386
FVB/NJ m 525.53 20.3688 567.569 483.491
KK/HlJ m 136.655 20.3688 178.694 94.616
MOLF/EiJ m 100.67 16.631 134.9947 66.3453
NZW/LacJ m 236.01 16.631 270.3347 201.6853
PWD/PhJ m 95.3 16.631 129.6247 60.9753
WSB/EiJ m 104.6 16.631 138.9247 70.2753




  GWAS USING LINEAR MIXED MODELS