Phenotype measure:   Rusyn5   liver_Ddit3_hfe

ID, description, units MPD:43062   liver_Ddit3_hfe   liver Ddit3 (formerly Chop), mRNA abundance relative to high-fat-only group   [%]
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure RNA expression profiling
Ontology mappings

  STRAIN COMPARISON PLOT
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Rusyn5 - liver Ddit3 (formerly Chop), mRNA abundance relative to high-fat-only group



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means155   %
Median of the strain means134   %
SD of the strain means± 83.7
Coefficient of variation (CV)0.542
Min–max range of strain means57.4   –   378   %
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 273783.646 21060.2805 6.6281 < 0.0001
Residuals 28 88967.6496 3177.4161


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 118.0 47.8   3 27.6 0.405 76.0, 170.0 -0.44
AKR/J m 157.0 36.7   3 21.2 0.233 117.0, 189.0 0.03
BALB/cByJ m 57.4 12.6   3 7.3 0.22 46.8, 71.4 -1.16
BALB/cJ m 152.0 70.5   3 40.7 0.463 79.6, 220.0 -0.03
BTBR T+ Itpr3tf/J m 96.6 61.5   3 35.5 0.636 51.3, 167.0 -0.69
C3H/HeJ m 93.4 49.7   3 28.7 0.532 53.8, 149.0 -0.73
C57BL/10J m 265.0 135.0   3 77.8 0.508 178.0, 420.0 1.32
DBA/2J m 79.4 52.2   3 30.1 0.658 42.8, 139.0 -0.9
FVB/NJ m 171.0 40.5   3 23.4 0.237 139.0, 217.0 0.2
KK/HlJ m 208.0 61.3   3 35.4 0.295 140.0, 260.0 0.64
MOLF/EiJ m 123.0 7.89   3 4.55 0.0641 116.0, 132.0 -0.38
NZW/LacJ m 378.0 36.7   3 21.2 0.097 336.0, 399.0 2.67
PWD/PhJ m 145.0 16.5   3 9.51 0.114 128.0, 161.0 -0.11
WSB/EiJ m 120.0 39.1   3 22.6 0.326 91.2, 164.0 -0.41


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 117.8333 32.5444 184.4975 51.1691
AKR/J m 157.47 32.5444 224.1342 90.8058
BALB/cByJ m 57.4067 32.5444 124.0709 0.0
BALB/cJ m 152.3033 32.5444 218.9675 85.6391
BTBR T+ Itpr3tf/J m 96.6033 32.5444 163.2675 29.9391
C3H/HeJ m 93.38 32.5444 160.0442 26.7158
C57BL/10J m 265.2933 32.5444 331.9575 198.6291
DBA/2J m 79.3867 32.5444 146.0509 12.7225
FVB/NJ m 170.9833 32.5444 237.6475 104.3191
KK/HlJ m 207.8 32.5444 274.4642 141.1358
MOLF/EiJ m 122.9933 32.5444 189.6575 56.3291
NZW/LacJ m 378.2733 32.5444 444.9375 311.6091
PWD/PhJ m 145.0 32.5444 211.6642 78.3358
WSB/EiJ m 119.84 32.5444 186.5042 53.1758




  GWAS USING LINEAR MIXED MODELS