Project measure / variable:   Rusyn5   liver_GSH_hf

ID, description, units MPD:43023   liver_GSH_hf   reduced liver glutathione (GSH)   [nmol/mg]  high-fat only  
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure metabolite quantification
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  STRAIN COMPARISON PLOT
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Rusyn5 - reduced liver glutathione (GSH) high-fat only



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means50.6   nmol/mg
Median of the strain means50.4   nmol/mg
SD of the strain means± 8.73
Coefficient of variation (CV)0.173
Min–max range of strain means34.6   –   68.8   nmol/mg
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 2967.6373 228.2798 2.3446 0.0287
Residuals 28 2726.1469 97.3624


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 34.6 3.93   3 2.27 0.114 30.7, 38.6 -1.83
AKR/J m 53.6 8.9   3 5.14 0.166 43.5, 60.1 0.35
BALB/cByJ m 48.3 8.33   3 4.81 0.172 41.5, 57.6 -0.26
BALB/cJ m 52.6 10.9   3 6.3 0.208 42.7, 64.3 0.23
BTBR T+ Itpr3tf/J m 41.9 5.23   3 3.02 0.125 36.1, 46.1 -0.99
C3H/HeJ m 55.3 4.52   3 2.61 0.0817 52.6, 60.5 0.54
C57BL/10J m 68.8 14.3   3 8.27 0.208 53.1, 81.1 2.09
DBA/2J m 52.0 9.73   3 5.62 0.187 43.8, 62.7 0.17
FVB/NJ m 43.6 5.12   3 2.96 0.117 40.7, 49.6 -0.8
KK/HlJ m 48.8 19.6   3 11.3 0.402 30.1, 69.2 -0.2
MOLF/EiJ m 47.2 10.4   3 6.03 0.221 40.1, 59.2 -0.38
NZW/LacJ m 63.3 1.88   3 1.09 0.0297 61.8, 65.4 1.46
PWD/PhJ m 54.1 13.3   3 7.67 0.246 38.8, 62.6 0.41
WSB/EiJ m 43.7 5.63   3 3.25 0.129 38.8, 49.9 -0.79


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 34.57 5.6969 46.2395 22.9005
AKR/J m 53.5733 5.6969 65.2428 41.9039
BALB/cByJ m 48.31 5.6969 59.9795 36.6405
BALB/cJ m 52.5667 5.6969 64.2361 40.8972
BTBR T+ Itpr3tf/J m 41.9467 5.6969 53.6161 30.2772
C3H/HeJ m 55.3333 5.6969 67.0028 43.6639
C57BL/10J m 68.8033 5.6969 80.4728 57.1339
DBA/2J m 51.9733 5.6969 63.6428 40.3039
FVB/NJ m 43.65 5.6969 55.3195 31.9805
KK/HlJ m 48.81 5.6969 60.4795 37.1405
MOLF/EiJ m 47.17 5.6969 58.8395 35.5005
NZW/LacJ m 63.26 5.6969 74.9295 51.5905
PWD/PhJ m 54.0967 5.6969 65.7661 42.4272
WSB/EiJ m 43.67 5.6969 55.3395 32.0005




  GWAS USING LINEAR MIXED MODELS