|
bw_d0 body weight, post infection
, day 0
63301
|
Female |
|
|
|
|
|
Male |
12 |
12 |
12 |
12 |
12 |
|
bw_d3 body weight, post infection
, day 3
63302
|
Female |
|
|
|
|
|
Male |
12 |
9 |
12 |
12 |
12 |
|
bw_d6 body weight, post infection
, day 6
63303
|
Female |
|
|
|
|
|
Male |
12 |
12 |
12 |
12 |
12 |
|
bw_d8 body weight, post infection
, day 8
63304
|
Female |
|
|
|
|
|
Male |
9 |
9 |
9 |
9 |
9 |
|
bw_d9 body weight, post infection
, day 9
63305
|
Female |
|
|
|
|
|
Male |
9 |
7 |
9 |
9 |
9 |
|
bw_d10 body weight, post infection
, day 10
63306
|
Female |
|
|
|
|
|
Male |
9 |
7 |
9 |
9 |
9 |
|
bw_d11 body weight, post infection
, day 11
63307
|
Female |
|
|
|
|
|
Male |
9 |
7 |
9 |
4 |
6 |
|
bw_d12 body weight, post infection
, day 12
63308
|
Female |
|
|
|
|
|
Male |
6 |
4 |
6 |
1 |
6 |
|
bw_d13 body weight, post infection
, day 13
63309
|
Female |
|
|
|
|
|
Male |
6 |
4 |
6 |
1 |
6 |
|
bw_d14 body weight, post infection
, day 14
63310
|
Female |
|
|
|
|
|
Male |
6 |
3 |
6 |
1 |
6 |
|
bw_d17 body weight, post infection
, day 17
63311
|
Female |
|
|
|
|
|
Male |
6 |
3 |
6 |
1 |
6 |
|
bw_d20 body weight, post infection
, day 20
63312
|
Female |
|
|
|
|
|
Male |
6 |
3 |
6 |
1 |
6 |
|
bw_d23 body weight, post infection
, day 23
63313
|
Female |
|
|
|
|
|
Male |
3 |
1 |
3 |
1 |
3 |
|
bw_d26 body weight, post infection
, day 26
63314
|
Female |
|
|
|
|
|
Male |
3 |
1 |
3 |
1 |
3 |
|
clin_score_d0 clinical score (0=healthy, 1=lethargic, 2=altered gait, 3=no movement, 4=moribund), post infection
, day 0
63315
|
Female |
|
|
|
|
|
Male |
12 |
12 |
12 |
12 |
12 |
|
clin_score_d3 clinical score (0=healthy, 1=lethargic, 2=altered gait, 3=no movement, 4=moribund), post infection
, day 3
63316
|
Female |
|
|
|
|
|
Male |
12 |
12 |
12 |
12 |
12 |
|
clin_score_d6 clinical score (0=healthy, 1=lethargic, 2=altered gait, 3=no movement, 4=moribund), post infection
, day 6
63317
|
Female |
|
|
|
|
|
Male |
12 |
12 |
12 |
12 |
12 |
|
clin_score_d8 clinical score (0=healthy, 1=lethargic, 2=altered gait, 3=no movement, 4=moribund), post infection
, day 8
63318
|
Female |
|
|
|
|
|
Male |
9 |
9 |
9 |
9 |
9 |
|
clin_score_d9 clinical score (0=healthy, 1=lethargic, 2=altered gait, 3=no movement, 4=moribund), post infection
, day 9
63319
|
Female |
|
|
|
|
|
Male |
9 |
8 |
9 |
9 |
9 |
|
clin_score_d10 clinical score (0=healthy, 1=lethargic, 2=altered gait, 3=no movement, 4=moribund), post infection
, day 10
63320
|
Female |
|
|
|
|
|
Male |
9 |
7 |
9 |
9 |
9 |
|
clin_score_d11 clinical score (0=healthy, 1=lethargic, 2=altered gait, 3=no movement, 4=moribund), post infection
, day 11
63321
|
Female |
|
|
|
|
|
Male |
9 |
7 |
9 |
4 |
9 |
|
clin_score_d12 clinical score (0=healthy, 1=lethargic, 2=altered gait, 3=no movement, 4=moribund), post infection
, day 12
63322
|
Female |
|
|
|
|
|
Male |
9 |
4 |
9 |
2 |
9 |
|
clin_score_d13 clinical score (0=healthy, 1=lethargic, 2=altered gait, 3=no movement, 4=moribund), post infection
, day 13
63323
|
Female |
|
|
|
|
|
Male |
6 |
4 |
6 |
1 |
6 |
|
clin_score_d14 clinical score (0=healthy, 1=lethargic, 2=altered gait, 3=no movement, 4=moribund), post infection
, day 14
63324
|
Female |
|
|
|
|
|
Male |
6 |
4 |
6 |
1 |
6 |
|
clin_score_d17 clinical score (0=healthy, 1=lethargic, 2=altered gait, 3=no movement, 4=moribund), post infection
, day 17
63325
|
Female |
|
|
|
|
|
Male |
6 |
3 |
6 |
1 |
6 |
|
clin_score_d20 clinical score (0=healthy, 1=lethargic, 2=altered gait, 3=no movement, 4=moribund), post infection
, day 20
63326
|
Female |
|
|
|
|
|
Male |
6 |
3 |
6 |
1 |
6 |
|
clin_score_d23 clinical score (0=healthy, 1=lethargic, 2=altered gait, 3=no movement, 4=moribund), post infection
, day 23
63327
|
Female |
|
|
|
|
|
Male |
3 |
1 |
3 |
1 |
3 |
|
clin_score_d26 clinical score (0=healthy, 1=lethargic, 2=altered gait, 3=no movement, 4=moribund), post infection
, day 26
63328
|
Female |
|
|
|
|
|
Male |
3 |
1 |
3 |
1 |
3 |
|
CD4_brain_d7 percentage of CD3+ T cells that are CD4+ in brain, post infection
, day 7
63329
|
Female |
|
|
|
|
|
Male |
3 |
3 |
3 |
3 |
3 |
|
CD4_brain_d12 percentage of CD3+ T cells that are CD4+ in brain, post infection
, day 12
63330
|
Female |
|
|
|
|
|
Male |
3 |
2 |
3 |
1 |
3 |
|
CD4_brain_d21 percentage of CD3+ T cells that are CD4+ in brain, post infection
, day 21
63331
|
Female |
|
|
|
|
|
Male |
3 |
2 |
3 |
|
3 |
|
CD4_brain_d28 percentage of CD3+ T cells that are CD4+ in brain, post infection
, day 28
63332
|
Female |
|
|
|
|
|
Male |
3 |
1 |
3 |
1 |
3 |
|
CD4_spleen_d7 percentage of CD3+ T cells that are CD4+ in spleen, post infection
, day 7
63333
|
Female |
|
|
|
|
|
Male |
3 |
|
|
|
3 |
|
CD4_spleen_d12 percentage of CD3+ T cells that are CD4+ in spleen, post infection
, day 12
63334
|
Female |
|
|
|
|
|
Male |
3 |
|
|
|
3 |
|
CD4_spleen_d21 percentage of CD3+ T cells that are CD4+ in spleen, post infection
, day 21
63335
|
Female |
|
|
|
|
|
Male |
3 |
|
|
|
3 |
|
CD4_spleen_d28 percentage of CD3+ T cells that are CD4+ in spleen, post infection
, day 28
63336
|
Female |
|
|
|
|
|
Male |
3 |
|
|
|
3 |
|
Treg_brain_d7 percentage of CD4+ T cells that are Foxp3+ in the brain, post infection
, day 7
63337
|
Female |
|
|
|
|
|
Male |
3 |
3 |
3 |
3 |
3 |
|
Treg_brain_d12 percentage of CD4+ T cells that are Foxp3+ in the brain, post infection
, day 12
63338
|
Female |
|
|
|
|
|
Male |
3 |
2 |
3 |
1 |
3 |
|
Treg_brain_d21 percentage of CD4+ T cells that are Foxp3+ in the brain, post infection
, day 21
63339
|
Female |
|
|
|
|
|
Male |
3 |
2 |
3 |
|
3 |
|
Treg_brain_d28 percentage of CD4+ T cells that are Foxp3+ in the brain, post infection
, day 28
63340
|
Female |
|
|
|
|
|
Male |
3 |
1 |
3 |
1 |
3 |
|
Treg_spleen_d7 percentage of CD4+ T cells that are Foxp3+ in the spleen, post infection
, day 7
63341
|
Female |
|
|
|
|
|
Male |
3 |
|
|
|
3 |
|
Treg_spleen_d12 percentage of CD4+ T cells that are Foxp3+ in the spleen, post infection
, day 12
63342
|
Female |
|
|
|
|
|
Male |
3 |
|
|
|
3 |
|
Treg_spleen_d21 percentage of CD4+ T cells that are Foxp3+ in the spleen, post infection
, day 21
63343
|
Female |
|
|
|
|
|
Male |
3 |
|
|
|
3 |
|
Treg_spleen_d28 percentage of CD4+ T cells that are Foxp3+ in the spleen, post infection
, day 28
63344
|
Female |
|
|
|
|
|
Male |
3 |
|
|
|
3 |
|
CD8_brain_d7 percentage of CD3+ T cells that are CD8+ in brain, post infection
, day 7
63345
|
Female |
|
|
|
|
|
Male |
3 |
3 |
3 |
3 |
3 |
|
CD8_brain_d12 percentage of CD3+ T cells that are CD8+ in brain, post infection
, day 12
63346
|
Female |
|
|
|
|
|
Male |
3 |
2 |
3 |
1 |
3 |
|
CD8_brain_d21 percentage of CD3+ T cells that are CD8+ in brain, post infection
, day 21
63347
|
Female |
|
|
|
|
|
Male |
3 |
2 |
3 |
|
3 |
|
CD8_brain_d28 percentage of CD3+ T cells that are CD8+ in brain, post infection
, day 28
63348
|
Female |
|
|
|
|
|
Male |
3 |
1 |
3 |
1 |
3 |
|
CD8_spleen_d7 percentage of CD3+ T cells that are CD8+ in spleen, post infection
, day 7
63349
|
Female |
|
|
|
|
|
Male |
3 |
|
|
|
3 |
|
CD8_spleen_d12 percentage of CD3+ T cells that are CD8+ in spleen, post infection
, day 12
63350
|
Female |
|
|
|
|
|
Male |
3 |
|
|
|
3 |
|
CD8_spleen_d21 percentage of CD3+ T cells that are CD8+ in spleen, post infection
, day 21
63351
|
Female |
|
|
|
|
|
Male |
3 |
|
|
|
3 |
|
CD8_spleen_d28 percentage of CD3+ T cells that are CD8+ in spleen, post infection
, day 28
63352
|
Female |
|
|
|
|
|
Male |
3 |
|
|
|
3 |
|
NS4b_brain_d7 percentage of CD3+ T cells that are NS4b+ in brain, post infection
, day 7
63353
|
Female |
|
|
|
|
|
Male |
3 |
3 |
3 |
3 |
3 |
|
NS4b_brain_d12 percentage of CD3+ T cells that are NS4b+ in brain, post infection
, day 12
63354
|
Female |
|
|
|
|
|
Male |
3 |
2 |
3 |
1 |
3 |
|
NS4b_brain_d21 percentage of CD3+ T cells that are NS4b+ in brain, post infection
, day 21
63355
|
Female |
|
|
|
|
|
Male |
3 |
2 |
3 |
|
3 |
|
NS4b_brain_d28 percentage of CD3+ T cells that are NS4b+ in brain, post infection
, day 28
63356
|
Female |
|
|
|
|
|
Male |
3 |
1 |
3 |
1 |
3 |
|
NS4b_spleen_d7 percentage of CD3+ T cells that are NS4b+ in spleen, post infection
, day 7
63357
|
Female |
|
|
|
|
|
Male |
3 |
|
|
|
3 |
|
NS4b_spleen_d12 percentage of CD3+ T cells that are NS4b+ in spleen, post infection
, day 12
63358
|
Female |
|
|
|
|
|
Male |
3 |
|
|
|
3 |
|
NS4b_spleen_d21 percentage of CD3+ T cells that are NS4b+ in spleen, post infection
, day 21
63359
|
Female |
|
|
|
|
|
Male |
3 |
|
|
|
3 |
|
NS4b_spleen_d28 percentage of CD3+ T cells that are NS4b+ in spleen, post infection
, day 28
63360
|
Female |
|
|
|
|
|
Male |
3 |
|
|
|
3 |
|
WNV_IgM_d7 virus-specific IgM in serum, post infection
, day 7
63361
|
Female |
|
|
|
|
|
Male |
3 |
3 |
3 |
3 |
3 |
|
WNV_IgM_d12 virus-specific IgM in serum, post infection
, day 12
63362
|
Female |
|
|
|
|
|
Male |
3 |
2 |
3 |
1 |
3 |
|
WNV_IgM_d21 virus-specific IgM in serum, post infection
, day 21
63363
|
Female |
|
|
|
|
|
Male |
3 |
2 |
3 |
|
3 |
|
WNV_IgM_d28 virus-specific IgM in serum, post infection
, day 28
63364
|
Female |
|
|
|
|
|
Male |
3 |
1 |
2 |
1 |
3 |
|
WNV_brain_d4 virus in brain, fold change compared to matched control, post infection
, day 4
63365
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
WNV_brain_d7 virus in brain, fold change compared to matched control, post infection
, day 7
63366
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
WNV_brain_d12 virus in brain, fold change compared to matched control, post infection
, day 12
63367
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
WNV_kidney_d2 virus in kidney, fold change compared to matched control, post infection
, day 2
63368
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
WNV_kidney_d4 virus in kidney, fold change compared to matched control, post infection
, day 4
63369
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
WNV_kidney_d7 virus in kidney, fold change compared to matched control, post infection
, day 7
63370
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
WNV_kidney_d12 virus in kidney, fold change compared to matched control, post infection
, day 12
63371
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
WNV_spleen_d2 virus in spleen, fold change compared to matched control, post infection
, day 2
63372
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
WNV_spleen_d4 virus in spleen, fold change compared to matched control, post infection
, day 4
63373
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
WNV_spleen_d7 virus in spleen, fold change compared to matched control, post infection
, day 7
63374
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
WNV_spleen_d12 virus in spleen, fold change compared to matched control, post infection
, day 12
63375
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifnb1_brain_d4 Ifnb1 gene expression in brain, fold change compared to matched control, post infection
, day 4
63376
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifnb1_brain_d7 Ifnb1 gene expression in brain, fold change compared to matched control, post infection
, day 7
63377
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifnb1_brain_d12 Ifnb1 gene expression in brain, fold change compared to matched control, post infection
, day 12
63378
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifnb1_kidney_d2 Ifnb1 gene expression in kidney, fold change compared to matched control, post infection
, day 2
63379
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifnb1_kidney_d4 Ifnb1 gene expression in kidney, fold change compared to matched control, post infection
, day 4
63380
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifnb1_kidney_d7 Ifnb1 gene expression in kidney, fold change compared to matched control, post infection
, day 7
63381
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifnb1_kidney_d12 Ifnb1 gene expression in kidney, fold change compared to matched control, post infection
, day 12
63382
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifnb1_spleen_d2 Ifnb1 gene expression in spleen, fold change compared to matched control, post infection
, day 2
63383
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifnb1_spleen_d4 Ifnb1 gene expression in spleen, fold change compared to matched control, post infection
, day 4
63384
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifnb1_spleen_d7 Ifnb1 gene expression in spleen, fold change compared to matched control, post infection
, day 7
63385
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifnb1_spleen_d12 Ifnb1 gene expression in spleen, fold change compared to matched control, post infection
, day 12
63386
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifit1_brain_d4 Ifit1 gene expression in brain, fold change compared to matched control, post infection
, day 4
63387
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifit1_brain_d7 Ifit1 gene expression in brain, fold change compared to matched control, post infection
, day 7
63388
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifit1_brain_d12 Ifit1 gene expression in brain, fold change compared to matched control, post infection
, day 12
63389
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifit1_kidney_d2 Ifit1 gene expression in kidney, fold change compared to matched control, post infection
, day 2
63390
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifit1_kidney_d4 Ifit1 gene expression in kidney, fold change compared to matched control, post infection
, day 4
63391
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifit1_kidney_d7 Ifit1 gene expression in kidney, fold change compared to matched control, post infection
, day 7
63392
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifit1_kidney_d12 Ifit1 gene expression in kidney, fold change compared to matched control, post infection
, day 12
63393
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifit1_spleen_d2 Ifit1 gene expression in spleen, fold change compared to matched control, post infection
, day 2
63394
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifit1_spleen_d4 Ifit1 gene expression in spleen, fold change compared to matched control, post infection
, day 4
63395
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifit1_spleen_d7 Ifit1 gene expression in spleen, fold change compared to matched control, post infection
, day 7
63396
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|
Ifit1_spleen_d12 Ifit1 gene expression in spleen, fold change compared to matched control, post infection
, day 12
63397
|
Female |
|
|
|
|
|
Male |
1 |
1 |
1 |
1 |
1 |
|