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QTL Archive

A collection of QTL studies across populations and species, curated by the Churchill Group to form the QTL Archive (qtlarchive@jax.org). Each study contains phenotype and genotype data for members of a population derived from a specific cross.

Each study page includes a list of phenotypes, associated MGI-curated genomic features, an Excel archive file and a .csv file formatted for use with R/qtl. Most pages include original analysis scripts and other files. Users can locate a data set of interest, download the data, and reproduce or extend analyses locally using software such as R/qtl, J/qtl, QTLRel, or DOQTL. Marker locations use Cox build 37 coordinates unless otherwise stated. QTL Archive resource funded by NIH R01 grant GM070683 to Gary Churchill.

QTL studies may be located by author or keyword using MPD search (above) or one of these list options:  


QTL Archive studies, by subject area
• appearance and coat color
• behavior     • anxiety-related     • balance and coordination     • circadian     • depression-related     • exploratory     • involuntary movement     • locomotor activity
• blood--clinical chemistry     • glucose     • proteins
• blood--hematology     • cell counts--RBC     • cell counts--WBC     • cell counts--WBC diffs     • hematocrit     • hemoglobin     • RBC parameters
• blood--lipids     • cholesterol--HDL     • cholesterol--LDL or non-HDL     • cholesterol--other     • cholesterol--total     • fatty acids     • phospholipid     • triglycerides
• blood--xenobiotics     • alcohol concentration
• body composition     • fat     • fluid     • lean     • total
• body fat pads
• body weight size and growth     • body mass index (BMI)     • body size     • body size and weight     • body weight     • body weight growth curve     • gut length     • tail length
• bone     • mineral content     • mineral density     • morphology     • strength
• brain     • morphology
• cancer     • tumor growth
• cardiovascular     • atherosclerosis     • blood pressure     • heart rate     • heart weight
• diabetes onset
• ear     • morphology
• endocrine and exocrine     • adrenal--morphology     • hormones
• eye     • morphology
• gallbladder     • pathology and gallstones
• immune system     • autoimmunity     • cell counts--peripheral blood     • immunoglobulins     • immunosuppression     • inflammation     • lymph node     • response to viral infection
• ingestive preference     • dietary
• kidney     • function     • morphology     • pathology
• liver     • pathology     • weight
• metabolism     • body temperature     • energy
• muscle     • skeletal--morphology
• nervous system     • development     • protein
• neurosensory     • nociception
• reproduction     • development     • fecundity     • male reproduction parameters
• respiratory     • airway resistance
• spleen     • weight


By drug, diet, or other intervention
• cocaine
• ethanol
• high-fat diet
• macronutrient diet option
• methacholine
• sodium chloride
• ultraviolet light
• western diet


QTL Archive data are also mapped to phenotyping methodology terms
as well as phenotype ontology terms.



 




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