Sugiyama2: Blood pressure in males of reciprocal backcrosses between C57BL/6J (salt-sensitive) and A/J (non-salt-sensitive) (2001)
Sugiyama F, Churchill GA, Higgins DC, Johns C, Makaritsis KP, Gavras H, Paigen B. Concordance of murine quantitative trait loci for salt-induced hypertension with rat and human loci.
Genomics. 2001 Jan 1;71(1):70-7.
Sen S, Churchill GA. A statistical framework for quantitative trait mapping.
Genetics. 2001 Sep;159(1):371-87.
Sugiyama2 downloads
QTL projects have several available downloads.
Use the QTL Data Downloads button near the bottom of this page.
QTL projects have several available downloads.
Use the QTL Data Downloads button near the bottom of this page.
Ontology terms mapped to Sugiyama2 measures:
| Investigators |
Fimihiro Sugiyama University of Tsukuba, Tsukuba JAPAN Gary A Churchill The Jackson Laboratory, Bar Harbor, ME |
| Participants | Sen S |
| Contact | Gary A Churchill gary.churchill@jax.org |
| Affiliated Center | QTL Archive |
| Acknowledgements | Funding provided by NIH HL55001, CA34196; Japanese Ministry of Education, Science, Sport, and Culture |
| QTL Archive data set | |
| MPD identifiers | Sugiyama2 MPD:119 |
| No updates/corrections. Initial release date: 01/2008. |
To investigate the genetic control of salt-induced hypertension, a QTL analysis was performed on male mice from a reciprocal backcross between the salt-sensitive C57BL/6J and the normotensive A/J inbred mouse strains. At 8 wks of age, progeny were provided with drinking water containing 1% NaCl for 2 wks. Blood pressure was measured using the tail cuff method. See Sugiyama et al, 2001 (below) for procedural details and sampling methods.
| Progenitor strains | A/J C57BL/6J |
| Cross type | Reciprocal backcross |
| Population size | 0 ♀ 250 ♂ |
| Age | 10wks |
Project / data set: Sugiyama2 a.k.a. Sugiyama_2001
Excel file: Data_Description_B6xA_BC_Sugiyama2001.xlsx
CSV file: Sugiyama2001_B6xA_BC_B37_Data.csv
Readme / text file: readme_Sugiyama2001.txt