Jarvis1: Mapping the epistatic network through F10 generation of an advanced intercross line between SM/J and LG/J (2011)

Jarvis JP, Cheverud JM. Mapping the epistatic network underlying murine reproductive fatpad variation. Genetics. 2011 Feb;187(2):597-610. Epub 2010 Nov 29.   PubMed 21115969     FullText

Jarvis1 downloads
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Participants J P Jarvis
James M Cheverud       Washington University School of Medicine St. Louis, MO
ContactJames M Cheverud     cheverud@pcg.wustl.edu
AffiliationChurchill Group QTL Archive
AcknowledgementsThis work was supported by a grant from the National Institutes of Health (DK-055736) and a doctoral dissertation improvement grant from the National Science Foundation (DEB-0608352).
Project type QTL Archive data set
MPD identifiersJarvis1     MPD:253
Data changelog No updates/corrections.       Initial release date: 04/2011.
To study genome-wide epistatic interactions and their contribution to complex trait variation, the authors investigated the reproductive fat pad weight in mice using the F10 generation of the LG, SM advanced intercross (AI) line. 1304 mice (660F+644M) were tested in experiment and multiple mapping techniques were applied in this research. The results provided important information about genetic architectures. For detailed protocols see Jarvis et al 2011.

QTL data set parameters:
Progenitor strains LG/J     SM/J    
Cross typeF10 of an advanced line
Population size 660 ♀     644 ♂
NotesF10 progeny
Age13wks and older

Measured phenotypes:       To access these data use the QTL Data Downloads button at bottom of page.
Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
Jarvis1 25301 fat pad weights (none) reproductive fatpad weight   [g]  Fat_g QTL population both 13wks and older N=652

Project / data set:   Jarvis1     a.k.a. Jarvis_2011
Excel file:   Data_Description_SMxLG_Jarvis2011.xlsx
CSV file:   Jarvis2011_SMxLG_B37_Data.csv
Readme / text file:   readme_Jarvis2011.txt
QC plots, figures, etc.:   MapComparison.png
QC plots, figures, etc.:   MarkerPlots.png
QC plots, figures, etc.:   RFplot.png
QC plots, figures, etc.:   chrRFplot001_Jarvis2011.png
QC plots, figures, etc.:   chrRFplot002_Jarvis2011.png
QC plots, figures, etc.:   chrRFplot003_Jarvis2011.png
QC plots, figures, etc.:   chrRFplot004_Jarvis2011.png
QC plots, figures, etc.:   chrRFplot005_Jarvis2011.png
QC plots, figures, etc.:   chrRFplot006_Jarvis2011.png
QC plots, figures, etc.:   chrRFplot007_Jarvis2011.png
QC plots, figures, etc.:   chrRFplot008_Jarvis2011.png
QC plots, figures, etc.:   chrRFplot009_Jarvis2011.png
QC plots, figures, etc.:   chrRFplot010_Jarvis2011.png
QC plots, figures, etc.:   chrRFplot011_Jarvis2011.png