MPD: Data set: Doorenbos1

Doorenbos1: Albuminuria QTL in the presence and absence of Apoe in 2 F2 intercross crosses (2008)

Doorenbos C, Tsaih SW, Sheehan S, Ishimori N, Navis G, Churchill G, Dipetrillo K, Korstanje R. Quantitative trait loci for urinary albumin in crosses between C57BL/6J and A/J inbred mice in the presence and absence of Apoe. Genetics. 2008 May;179(1):693-9. PubMed 18493081

Doorenbos1 downloads
QTL projects have several available downloads.
Use the QTL Data Downloads button near the bottom of this page.

Ontology terms mapped to Doorenbos1 measures:

MA:0002545 urine
MP:0001259 abnormal body weight
MP:0011469 abnormal urine creatinine level
MP:0020153 abnormal urine albumin level
VT:0001259 body mass
VT:0001757 urine molecular composition trait
VT:0002871 urine albumin amount
VT:0010540 urine creatinine amount

Investigators	C Doorenbos Gary A Churchill The Jackson Laboratory, Bar Harbor, ME
Participants	Tsaih SW, Sheehan S, Ishimori N, Navis G, Dipetrillo K, Korstanje R
Contact	Gary A Churchill gary.churchill@jax.org
Affiliated Center	QTL Archive
Acknowledgements	This work was supported by National Institute of Diabetes and Digestive and Kidney Diseases grant DK-69381 and National Institute of General Medical Sciences grant GM-070683.
Project type	QTL Archive data set
MPD identifiers	Doorenbos1 MPD:208
Data changelog	No updates/corrections. Initial release date: 10/2009.

This project is to identify the genetic loci that control albuminuria in mouse crosses in the presence and abscence of Apoe. For detailed protocols see Doorenbos et al 2008.

QTL data set parameters:

Cross 1: B6 and A/J Doorenbos1
Progenitor strains	A/J C57BL/6J
Cross direction notation	(B6xA) F1 x (B6xA) F1
Cross type	F2 intercross
Population size	0 ♀ 383 ♂
Age	8-10wks

Progenitor strains	A/J C57BL/6J.Apoe^-/-
Cross type	None
Population size	None ♀ None ♂
Age	8-10wks

Measured phenotypes: To access these data use the QTL Data Downloads button at bottom of page.

Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	Sex	Age	Sample Size (Avg)
Doorenbos1	urinalysis	(none)	urinary creatinine [mg/dL] UCreat 20801	QTL population	m	8-10wks	N=383

Doorenbos1	urinalysis	(none)	microalbumin [mg/dL] Microalb 20802	QTL population	m	8-10wks	N=383

Doorenbos1	urinalysis	(none)	albumin/creatinine ratio [mg/g] Alb/Creat 20803	QTL population	m	8-10wks	N=383

Doorenbos1	body weight	(none)	Body Weight [g] BW 20804	QTL population	m	8-10wks	N=383

Associated genomic features

MGI-curated QTL / genomic features that have been associated with this data set:
Albq1 Albq2 Albq3 Albq4

Cross 1: B6 and A/J Doorenbos1 a.k.a. Doorenbos_2008a
Excel file: ._Data_Description_BxA_Doorenbos2008a.xlsx
Excel file: Data_Description_BxA_Doorenbos2008a.xlsx
CSV file: Doorenbos2008a_BxA_B37_Data.csv
Readme / text file: ._readme.txt
Readme / text file: readme_Doorenbos2008a.txt
QC plots, figures, etc.: QCReport_Doorenbos2008a.pdf

Project / data set: Doorenbos1b a.k.a. None

QTL file list not available on this MPD instance.