Dzur-Gejdosova1: Dissecting the genetic architecture of F1 hybrid sterility in PWD/Ph and C57BL/6J backcross (2012)

Dzur-Gejdosova1 M, Simecek P

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Participants M Dzur-Gejdosova1
Petr Simecek       The Jackson Laboratory Bar Harbor, ME
ContactPetr Simecek
AffiliationChurchill Group QTL Archive
AcknowledgementsThis work was supported by the Academy of Sciences of the Czech Republic (Praemium Academiae to JF) and by the Ministry of Education, Youth and Sports of the Czech Republic (COST LD11079). MD-G and TB are PhD students supported in part by the Faculty of Science, Charles University, Prague.
Project type QTL Archive data set
MPD identifiersDzur-Gejdosova1     MPD:272
Data changelog No updates/corrections.       Initial release date: 02/2012.
To study the genetic architecture of F1 hybrid sterility between house mouse Mus m. domesticus and Mus m. musculus, QTL analysis of a backcross between inbred strains (PWD, B6) representing the two subspecies was conducted. Segregation of hybrid sterility genes was analyzed in 254 male backcross progeny of (PWDxB6) F1 females mated to B6 males. For detailed protocols see the publication of Dzur-Gejdosova et al 2012 (Evolution online accepted articles, 2012).

QTL data set parameters:
Progenitor strains C57BL/6J     PWD/PhJ    
Cross direction notation(PWDxB6) x B6
Cross typeBackcross
Population size 0 ♀     254 ♂

Measured phenotypes:       To access these data use the QTL Data Downloads button at bottom of page.
Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
Dzur-Gejdosova1 27201 body weight (none) body weight   [g]  BW QTL population m 9wks N=254
Dzur-Gejdosova1 27202 organ weights (none) testes weight   [mg]  TW QTL population m 9wks N=254
Dzur-Gejdosova1 27203 microscopy (none) sperm cells counted in Bürker chamber   [millions]  SC QTL population m 9wks N=254

Project / data set:   Dzur-Gejdosova1     a.k.a. Dzur-Gejdosova_2012
Excel file:   Data_Description_PWDxB6_BC_Dzur-Gejdosova2012.xlsx
CSV file:   Dzur-Gejdosova2012_PWDxB6_BC_B37_Data.csv
Readme / text file:   readme_Dzur-Gejdosova2012.txt
QC plots, figures, etc.:   QCReport_Dzur-Gejdosova2012.pdf