Studies involving Collaborative Cross 8 founders
    • List CC8 strains

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Data set Procedure What's in this data set Panel Sex Age (weeks) Year
Benavides1 genotype assessment Gpr84 allele assessment. PCR, sequencing. inbred w/CC8   (58) both 6wks 2013
CGDpheno1 body size and weight Body weight and length. inbred w/CC8   (72) both 10-13wks 2009
CGDpheno1 complete blood count Hematology. inbred w/CC8   (72) both 10-13wks 2009
CGDpheno1 DXA Body mass, fat mass, lean mass, bone mineral density. inbred w/CC8   (72) both 10-13wks 2009
CGDpheno1 lipid profile Cholesterol, HDL, triglycerides, free fatty acids. 4h fast, plasma. inbred w/CC8   (72) both 10-13wks 2009
CGDpheno1 metabolic panel Clinical blood chemistry (plasma). 4h fast. inbred w/CC8   (72) both 10-13wks 2009
CGDpheno3 body weight Body weight CC diallel w/par   (62) both 8-16wks 2012
CGDpheno3 complete blood count Hematology. CC diallel w/par   (62) both 8-16wks 2012
CGDpheno3 DXA Body mass, fat mass, lean mass, bone mineral density and content, bone area. CC diallel w/par   (62) both 8-16wks 2012
CGDpheno3 ECG Wave amplitudes and intervals. Conscious. CC diallel w/par   (62) both 8-16wks 2012
CGDpheno3 lipid profile Cholesterol, HDL, triglycerides. 4h fast, plasma. CC diallel w/par   (62) both 8-16wks 2012
CGDpheno3 metabolic panel Glucose (plasma). 4h fast. CC diallel w/par   (62) both 8-16wks 2012
CGDpheno3 tail cuff Heart rate and blood pressure. Conscious mice. CC diallel w/par   (62) both 8-16wks 2012
Chesler2 behavior observation Wildness scoring. CC diallel w/par   (62) both 7-15wks 2011
Chesler2 body size and weight Body weight, body length, tail length. CC diallel w/par   (62) both 7-15wks 2011
Chesler2 colony observation Reproduction, fecundity. CC diallel w/par   (62) both 7-15wks 2011
Chesler2 complete blood count Hematology. CC diallel w/par   (62) both 7-15wks 2011
Chesler2 fat pad weights Gonadal fat pad weight. CC diallel w/par   (62) both 7-15wks 2011
Chesler2 light-dark box Anxiety, avoidance behavior. 10 min test. CC diallel w/par   (62) both 7-15wks 2011
Chesler2 metabolic panel Clinical blood chemistry. 16h fast. CC diallel w/par   (62) both 7-15wks 2011
Chesler2 monitoring system Sleep patterns. Dark period, total, peak activity. Baseline and after sleep deprivation. CC diallel w/par   (62) both 7-15wks 2011
Chesler2 nociception assay Hot plate and pressure on tail. CC diallel w/par   (62) both 7-15wks 2011
Chesler2 open field test Locomotor activity, exploratory, anxiety-related behavior. 10 min test. CC diallel w/par   (62) both 7-15wks 2011
Chesler2 organ weights Heart, kidney weights. CC diallel w/par   (62) both 7-15wks 2011
Chesler3 behavior observation Wildness scoring. CC pre w/par   (367) both 7-15wks 2011
Chesler3 body size and weight Body weight, tail length. CC pre w/par   (367) both 7-15wks 2011
Chesler3 bone dimensions Femur. CC pre w/par   (367) both 7-15wks 2011
Chesler3 colony observation Reproduction, fecundity. CC pre w/par   (367) both 7-15wks 2011
Chesler3 complete blood count Hematology. CC pre w/par   (367) both 7-15wks 2011
Chesler3 fat pad weights Gonadal fat pad weights. CC pre w/par   (367) both 7-15wks 2011
Chesler3 light-dark box Anxiety, avoidance behavior. 10 min test. CC pre w/par   (367) both 7-15wks 2011
Chesler3 metabolic panel Clinical blood chemistry. 16h fast. CC pre w/par   (367) both 7-15wks 2011
Chesler3 monitoring system Sleep patterns. Dark period, total, peak activity. Baseline and after sleep deprivation. CC pre w/par   (367) both 7-15wks 2011
Chesler3 nociception assay Hot plate and pressure on tail. CC pre w/par   (367) both 7-15wks 2011
Chesler3 open field test Locomotor activity, exploratory, anxiety-related behavior. 10 min test. CC pre w/par   (367) both 7-15wks 2011
Chesler3 organ dimensions Kidney length and volume. CC pre w/par   (367) both 7-15wks 2011
Chesler3 organ weights Heart, brain, kidney, spleen, gonadal fat pads, testicle weights. CC pre w/par   (367) both 7-15wks 2011
Chesler4 body weight Body weight DO population w/par   (9) both 12-16wks 2013
Chesler4 light-dark box Anxiety, avoidance behavior. 20 min test. DO population w/par   (9) both 12-16wks 2013
Chesler4 nociception assay Hot plate. DO population w/par   (9) both 12-16wks 2013
Chesler4 open field test Locomotor activity, exploratory, anxiety-related behavior. 20 min test. DO population w/par   (9) both 12-16wks 2013
Chesler4 tail suspension test Frequency climbing, time immobile, latency immobile. 5 min test. DO population w/par   (9) both 12-16wks 2013
Chesler4 visual cliff Anxiety, avoidance behavior. 20 min test. DO population w/par   (9) both 12-16wks 2013
Collins1 complete blood count Hematology. CC pre w/par   (139) m 10-14wks 2012
Crowley1 behavior observation
with haloperidol
Observed involuntary repetitive movement. Baseline vs. during and after haloperidol 60d implant (several timepoints). inbred w/CC8   (27) m 9-28wks 2012
Crowley1 body weight
with haloperidol
Baseline vs. after haloperidol 60d implant. inbred w/CC8   (27) m 9-28wks 2012
Crowley1 drug and metabolite quantification
with haloperidol
Haloperidol concentration (plasma). Baseline vs. during and after haloperidol 60d implant (several timepoints). inbred w/CC8   (27) m 9-28wks 2012
Crowley1 inclined screen test
with haloperidol
Baseline vs. during and after haloperidol 60d implant (several timepoints). inbred w/CC8   (27) m 9-28wks 2012
Crowley1 open field test
with haloperidol
Locomotor activity, exploratory behavior, involuntary movement. Baseline vs. haloperidol 60d implant (several timepoints). 60 min test. inbred w/CC8   (27) m 9-28wks 2012
DiPetrillo2 urinalysis Microalbumin, creatinine, ratio. CC pre w/par   (163) m 10wks 2012
Ferris1 body weight
with influenza A (H1N1) virus
Body weight CC pre w/par   (163) f 8-16wks 2012
Ferris1 health assessment
with influenza A (H1N1) virus
Clinical health assessment score and strain susceptibility index 4 days after infection with influenza A (H1N1) virus. CC pre w/par   (163) f 8-16wks 2012
Ferris1 histopathology
with influenza A (H1N1) virus
Lungs and airway 4 days after infection with influenza A (H1N1) virus. CC pre w/par   (163) f 8-16wks 2012
Ferris1 in vitro assay
with influenza A (H1N1) virus
Viral replication log titer 4 days after infection with influenza A (H1N1) virus. In vitro. CC pre w/par   (163) f 8-16wks 2012
Lesage1 immune cell quantification Immunological cell variation. CC w/par   (76) both 5-8wks 2018
Mathes1 body weight
with exercise
Baseline vs. after exercise (access to running wheel). CC pre w/par   (184) m 10-12wks 2011
Mathes1 intake monitoring
with exercise
Caloric intake. Baseline vs. after exercise (access to running wheel). Metabolism, food intake. CC pre w/par   (184) m 10-12wks 2011
Mathes1 monitoring system
with exercise
Respiratory exchange ratio. Baseline (before access to running wheel). CC pre w/par   (184) m 10-12wks 2011
Mathes1 MRI
with exercise
Body composition (percent fat). Baseline vs. after exercise (access to running wheel). CC pre w/par   (184) m 10-12wks 2011
Mathes1 running wheel monitoring
with exercise
Distance, speed at days 1, 6, and 12. CC pre w/par   (184) m 10-12wks 2011
Morgan1 body weight
with high-fat diet and olanzapine
Body weight and growth curve from age 8wks to 18wks weighed every 2wks. Olanzapine vs. control (both groups high-fat diet). inbred w/CC8   (9) f 8-18wks 2014
Odet2 microscopy Male reproductive sperm motility. inbred w/CC8   (8) m 10-66wks 2015
Powell1 in vitro assay
with Neisseria musculi
Bacterial load after inoculation with Neisseria musculi. Oral cavity. inbred w/CC8   (8) both 8-16wks 2018
Schughart3 body weight
with influenza A (H3N2) virus
Influenza A (H3N2) virus (several doses) vs. baseline. Several timepoints. inbred w/CC8   (8) both 7-13wks 2013
Schughart3 health assessment
with influenza A (H3N2) virus
Survival rate, susceptibility, influenza A (H3N2) virus (several doses). inbred w/CC8   (8) both 7-13wks 2013
Schughart4 body weight
with influenza A (H3N2) virus
Influenza A (H3N2) virus vs. controls. Several timepoints. inbred w/CC8   (8) f 8-12wks 2016
Schughart4 complete blood count
with influenza A (H3N2) virus
White blood cell count and differentials. Influenza A (H3N2) virus vs. controls. inbred w/CC8   (8) f 8-12wks 2016
Schughart4 in vitro assay
with influenza A (H3N2) virus
Viral load in lungs after infection with influenza A (H3N2) virus. inbred w/CC8   (8) f 8-12wks 2016
Schughart5 body weight
with influenza A (H3N2) virus
Influenza A (H3N2) virus vs. controls. Several timepoints. inbred w/CC8   (8) f 8-12wks 2016
Schughart5 organ weights
with influenza A (H3N2) virus
Lung weight. Animals infected with influenza A (H3N2) virus vs. controls. inbred w/CC8   (8) f 8-12wks 2016
Shorter3 colony observation Litter size assessment. CC diallel w/par   (62) f 3wks 2018
Sunde1 body weight Body weight curve 3 to 12 wks, control group. inbred w/CC8   (8) m 3-14wks 2018
Sunde1 RNA expression profiling Selenium regulation of selenoprotein enzyme activity and transcripts. inbred w/CC8   (8) m 3-14wks 2018
UNC-MMUGA2 genotyping SNP profiling, 76,000+ genomic locations, 1-19,X,MT CC w/par   (77) both 2017