GMC08: Transepidermal water loss in 8 inbred founder strains of the Collaborative Cross (2020)

German Mouse Clinic and Department of Infection Genetics, HZI   GMC Management Team   With: Hrabě de Angelis M, Fuchs H, Gailus-Durner V, Aguilar-Pimentel A, Ollert M, Lengger C, Kollmus H, Schughart K

          List all GMC measures
GMC08 downloads
• Download GMC08 project data set     one row per animal, one column per trait (uploaded by Curator)
• Download GMC08 individual animal data     one row per animal, one column per trait (generated from data)
• Download GMC08 strain means, SD, N, etc.     one row per strain/sex/measure (generated from data)
• GMC08 supplementary data
Institutional authorship German Mouse Clinic and Department of Infection Genetics, HZI     Lab web site
Investigators GMC Management Team       German Mouse Clinic,  Neuherberg GERMANY
Participants Hrabě de Angelis M, Fuchs H, Gailus-Durner V, Aguilar-Pimentel A, Ollert M, Lengger C, Kollmus H, Schughart K
ContactGMC Management Team     coregmc@helmholtz-muenchen.de     Lab web site
Affiliated CenterGerman Mouse Clinic (GMC)
AcknowledgementsFunding provided by German Ministry of Education and Research (Infrafrontier Grant 01KX1012) to GMC and by intramural grants from the Helmholtz Association (Program Infection and Immunity) to KS
Project type Phenotype strain survey data set
MPD identifiersGMC08     MPD:557
Data changelog No updates/corrections.       Initial release date: 02/2020.
Formatted citation
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Transepidermal water loss (TEWL) is defined as the measurement of the quantity of water that passes from inside the body through the epidermal layer to the surrounding atmosphere via diffusion and evaporation processes. Measurements of TEWL are useful for identifying skin damage caused by pathological conditions such as eczema, chemical exposure, or physical insult, as rates of TEWL increase in proportion to the level of damage.

Summary of procedures that were conducted
• transepidermal water loss test Transepidermal water loss in condenser chamber.
Mice: inbred w/CC8   8 strains   ♀♂   age 11-12wks   5 experimental groups