GMC20: Circulating immunoglobulins, rheumatoid factor, and anti-DNA antibodies in 8 inbred founder strains of the Collaborative Cross (2020)

Kollmus H, Fuchs H, Lengger C, Haselimashhadi H, Bogue MA, Östereicher MA, Horsch M, Adler T, Aguilar-Pimentel JA, Amarie OV, Becker L, Beckers J, Calzada-Wack J, Garrett L, Hans W, Hölter SM, Klein-Rodewald T, Maier H, Mayer-Kuckuk P, Miller G, Moreth K, Neff F, Rathkolb B, Rácz I, Rozman J, Spielmann N, Treise I, Busch D, Graw J, Klopstock T, Wolf E, Wurst W, Yildirim AÖ, Mason J, Torres A, Mouse Phenome Database Team., Balling R, Mehaan T, Gailus-Durner V, Schughart K, Hrabě de Angelis M. A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes. Mamm Genome. 2020 Feb;31(1-2):30-48. doi: 10.1007/s00335-020-09827-3. Epub 2020 Feb 14.   PubMed 32060626     FullText


          List all GMC measures
GMC20 downloads
• Download GMC20 project data set     animal data, as uploaded
• Download GMC20 animal data matrix     with factor-related expansion applied as necessary
• Download GMC20 strain means, SD, N, etc.     one row per strain/sex/measure
Institutional authorship German Mouse Clinic and Department of Infection Genetics, HZI     Lab web site
Investigators GMC Management Team       German Mouse Clinic,  Neuherberg GERMANY
Participants Hrabě de Angelis M, Fuchs H, Gailus-Durner V, Adler T, Treise I, Busch D, Aguilar-Pimentel A, Ollert M, Lengger C, Kollmus H, Schughart K
ContactGMC Management Team     coregmc@helmholtz-muenchen.de     Lab web site
Affiliated CenterGerman Mouse Clinic (GMC)
AcknowledgementsFunding provided by German Ministry of Education and Research (Infrafrontier Grant 01KX1012) to GMC and by intramural grants from the Helmholtz Association (Program Infection and Immunity) to KS
Project type Phenotype strain survey data set
MPD identifiersGMC20     MPD:569
Data changelog No updates/corrections.       Initial release date: 02/2020.
Formatted citation
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Experimental groups in this study:
• None     • None     • None     • None    

Procedures conducted:
• immunoglobulin quantification  Immunoglobulins (plasma).
• autoantibody quantification  Anti-DNA autoantibodies, rheumatoid factor.

Mice: inbred w/CC8   8 strains   ♀♂   age 16-17, 20-21wks   4 experimental groups