GMC01: Locomotor activity and exploratory and anxiety-related behaviors assessed by the open field test in 8 inbred founder strains of the Collaborative Cross (2020)

German Mouse Clinic and Department of Infection Genetics, HZI   GMC Management Team   With: Hrabě de Angelis M, Fuchs H, Gailus-Durner V, Garrett L, Hölter-Koch S, Wurst W, Lengger C, Kollmus H, Schughart K

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Institutional authorship German Mouse Clinic and Department of Infection Genetics, HZI     Lab web site
Investigators GMC Management Team       German Mouse Clinic,  Neuherberg GERMANY
Participants Hrabě de Angelis M, Fuchs H, Gailus-Durner V, Garrett L, Hölter-Koch S, Wurst W, Lengger C, Kollmus H, Schughart K
ContactGMC Management Team     coregmc@helmholtz-muenchen.de     Lab web site
Affiliated CenterGerman Mouse Clinic (GMC)
AcknowledgementsFunding provided by German Ministry of Education and Research (Infrafrontier Grant 01KX1012) to GMC and by intramural grants from the Helmholtz Association (Program Infection and Immunity) to KS
Project type Phenotype strain survey data set
MPD identifiersGMC01     MPD:550
Data changelog No updates/corrections.       Initial release date: 02/2020.
Formatted citation
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The open field test is used to assess anxiety-related and exploratory behaviors. It is based on the natural tendency of an animal to explore and to protect itself which, in this test, translates to spending more time in the periphery of the open field arena than in the center.

Summary of procedures that were conducted
• open field test Locomotor, exploratory, and anxiety-related behavior. 20 min test some at 5 min intervals.
Mice: inbred w/CC8   8 strains   ♀♂   age 8-9wks   5 experimental groups