|
Bcells_BEZ_ctrl B cells, percent viability
, control
52401
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Bcells_BEZ_A B cells, percent viability
, dose: 0.046 µM
52402
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Bcells_BEZ_B B cells, percent viability
, dose: 0.137 µM
52403
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Bcells_BEZ_C B cells, percent viability
, dose: 1.235 µM
52404
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Bcells_BEZ_D B cells, percent viability
, dose: 11.1 µM
52405
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Bcells_BEZ_E B cells, percent viability
, dose: 100 µM
52406
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Tcells_BEZ_ctrl T cells, percent viability
, control
52407
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Tcells_BEZ_A T cells, percent viability
, dose: 0.046 µM
52408
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Tcells_BEZ_B T cells, percent viability
, dose: 0.137 µM
52409
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Tcells_BEZ_C T cells, percent viability
, dose: 1.235 µM
52410
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Tcells_BEZ_D T cells, percent viability
, dose: 11.1 µM
52411
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Tcells_BEZ_E T cells, percent viability
, dose: 100 µM
52412
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
monocytes_BEZ_ctrl monocytes, percent viability
, control
52413
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
monocytes_BEZ_A monocytes, percent viability
, dose: 0.046 µM
52414
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
monocytes_BEZ_B monocytes, percent viability
, dose: 0.137 µM
52415
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
monocytes_BEZ_C monocytes, percent viability
, dose: 1.235 µM
52416
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
monocytes_BEZ_D monocytes, percent viability
, dose: 11.1 µM
52417
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
monocytes_BEZ_E monocytes, percent viability
, dose: 100 µM
52418
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Bcells_Dox_ctrl B cells, percent viability
, control
52421
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Bcells_Dox_A B cells, percent viability
, dose: 0.046 µM
52422
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Bcells_Dox_B B cells, percent viability
, dose: 0.137 µM
52423
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Bcells_Dox_C B cells, percent viability
, dose: 1.235 µM
52424
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Bcells_Dox_D B cells, percent viability
, dose: 11.1 µM
52425
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
3 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Bcells_Dox_E B cells, percent viability
, dose: 100 µM
52426
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
1 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Tcells_Dox_ctrl T cells, percent viability
, control
52427
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Tcells_Dox_A T cells, percent viability
, dose: 0.046 µM
52428
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Tcells_Dox_B T cells, percent viability
, dose: 0.137 µM
52429
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Tcells_Dox_C T cells, percent viability
, dose: 1.235 µM
52430
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Tcells_Dox_D T cells, percent viability
, dose: 11.1 µM
52431
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
3 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Tcells_Dox_E T cells, percent viability
, dose: 100 µM
52432
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
1 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
monocytes_Dox_ctrl monocytes, percent viability
, control
52433
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
monocytes_Dox_A monocytes, percent viability
, dose: 0.046 µM
52434
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
monocytes_Dox_B monocytes, percent viability
, dose: 0.137 µM
52435
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
monocytes_Dox_C monocytes, percent viability
, dose: 1.235 µM
52436
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
monocytes_Dox_D monocytes, percent viability
, dose: 11.1 µM
52437
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
3 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
monocytes_Dox_E monocytes, percent viability
, dose: 100 µM
52438
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
1 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Bcells_Ida_ctrl B cells, percent viability
, control
52441
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Bcells_Ida_A B cells, percent viability
, dose: 0.046 µM
52442
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
3 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Bcells_Ida_B B cells, percent viability
, dose: 0.137 µM
52443
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
3 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Bcells_Ida_C B cells, percent viability
, dose: 1.235 µM
52444
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
3 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Bcells_Ida_D B cells, percent viability
, dose: 11.1 µM
52445
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
3 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Bcells_Ida_E B cells, percent viability
, dose: 100 µM
52446
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Tcells_Ida_ctrl T cells, percent viability
, control
52447
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Tcells_Ida_A T cells, percent viability
, dose: 0.046 µM
52448
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
3 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Tcells_Ida_B T cells, percent viability
, dose: 0.137 µM
52449
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
3 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Tcells_Ida_C T cells, percent viability
, dose: 1.235 µM
52450
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
3 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Tcells_Ida_D T cells, percent viability
, dose: 11.1 µM
52451
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
3 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Tcells_Ida_E T cells, percent viability
, dose: 100 µM
52452
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
monocytes_Ida_ctrl monocytes, percent viability
, control
52453
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
monocytes_Ida_A monocytes, percent viability
, dose: 0.046 µM
52454
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
3 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
monocytes_Ida_B monocytes, percent viability
, dose: 0.137 µM
52455
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
3 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
monocytes_Ida_C monocytes, percent viability
, dose: 1.235 µM
52456
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
3 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
monocytes_Ida_D monocytes, percent viability
, dose: 11.1 µM
52457
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
3 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
monocytes_Ida_E monocytes, percent viability
, dose: 100 µM
52458
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
|
4 |
4 |
4 |
4 |
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
3 |
|
Bcells_Sel_ctrl B cells, percent viability
, control
52461
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Bcells_Sel_A B cells, percent viability
, dose: 0.046 µM
52462
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Bcells_Sel_B B cells, percent viability
, dose: 0.137 µM
52463
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Bcells_Sel_C B cells, percent viability
, dose: 1.235 µM
52464
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Bcells_Sel_D B cells, percent viability
, dose: 11.1 µM
52465
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Bcells_Sel_E B cells, percent viability
, dose: 100 µM
52466
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Tcells_Sel_ctrl T cells, percent viability
, control
52467
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Tcells_Sel_A T cells, percent viability
, dose: 0.046 µM
52468
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Tcells_Sel_B T cells, percent viability
, dose: 0.137 µM
52469
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Tcells_Sel_C T cells, percent viability
, dose: 1.235 µM
52470
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Tcells_Sel_D T cells, percent viability
, dose: 11.1 µM
52471
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
Tcells_Sel_E T cells, percent viability
, dose: 100 µM
52472
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
monocytes_Sel_ctrl monocytes, percent viability
, control
52473
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
monocytes_Sel_A monocytes, percent viability
, dose: 0.046 µM
52474
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
monocytes_Sel_B monocytes, percent viability
, dose: 0.137 µM
52475
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
monocytes_Sel_C monocytes, percent viability
, dose: 1.235 µM
52476
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
monocytes_Sel_D monocytes, percent viability
, dose: 11.1 µM
52477
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|
monocytes_Sel_E monocytes, percent viability
, dose: 100 µM
52478
|
(F) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
(M) |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
2 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
4 |
|
3 |
|