Project measure / variable:   Wiltshire4   monocytes_Dox_D

ID, description, units MPD:52437   monocytes_Dox_D   monocytes, percent viability   [%]  dose: 11.1 µM  
doxorubicin study
Data set, strains Wiltshire4   inbred w/CC7   35 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - monocytes, percent viability dose: 11.1 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means30.1   %
Median of the strain means27.4   %
SD of the strain means± 16.3
Coefficient of variation (CV)0.543
Min–max range of strain means11.0   –   76.6   %
Mean sample size per strain3.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 31891.7068 937.9914 12.9416 < 0.0001
Residuals 101 7320.3578 72.4788


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 43.4 9.06   4 4.53 0.209 32.0, 52.9 0.82
129X1/SvJ m 46.8 9.29   4 4.64 0.198 34.5, 54.6 1.02
A/J m 19.9 5.2   4 2.6 0.261 14.7, 26.9 -0.62
AKR/J m 32.5 3.86   4 1.93 0.119 28.6, 37.7 0.15
BALB/cByJ m 64.5 11.4   4 5.7 0.177 54.8, 76.8 2.11
BTBR T+ Itpr3tf/J m 21.7 8.18   4 4.09 0.377 16.6, 33.9 -0.51
C3H/HeJ m 26.0 11.6   4 5.81 0.446 9.87, 37.4 -0.25
C57BL/6J m 11.0 4.46   4 2.23 0.404 5.81, 16.6 -1.17
C57BLKS/J m 22.5 5.9   4 2.95 0.262 16.1, 29.7 -0.46
C57BR/cdJ m 19.1 6.72   4 3.36 0.351 9.76, 25.1 -0.67
C58/J m 25.0 0.665   2   0.47 0.0266 24.5, 25.4 -0.31
CBA/J m 27.8 1.24   4 0.62 0.0446 26.8, 29.6 -0.14
CZECHII/EiJ m 17.9 3.65   4 1.82 0.204 14.3, 22.5 -0.75
DBA/2J m 12.7 6.92   4 3.46 0.547 6.81, 22.1 -1.07
FVB/NJ m 35.8 8.77   4 4.39 0.245 27.4, 43.9 0.35
I/LnJ m 30.6 11.6   4 5.81 0.379 18.0, 44.9 0.03
KK/HlJ m 76.6 1.89   3 1.09 0.0247 74.5, 77.8 2.85
LG/J m 31.3 7.37   4 3.69 0.235 22.9, 38.8 0.07
LP/J m 14.6 3.01   4 1.51 0.206 11.2, 18.2 -0.95
MA/MyJ m 15.5 4.86   4 2.43 0.314 8.94, 20.4 -0.89
NOD/ShiLtJ m 11.3 1.57   4 0.783 0.138 9.68, 12.8 -1.15
NON/ShiLtJ m 27.4 6.89   4 3.45 0.251 19.9, 35.8 -0.16
NZB/BlNJ m 21.0 2.24   4 1.12 0.107 18.3, 23.2 -0.56
NZO/HlLtJ m 35.0 6.25   4 3.12 0.179 26.4, 40.6 0.3
NZW/LacJ m 31.7 4.38   4 2.19 0.138 27.5, 37.8 0.1
PERA/EiJ m 17.4 2.86   4 1.43 0.164 15.4, 21.5 -0.78
PL/J m 21.6 0.425   4 0.212 0.0196 21.2, 22.2 -0.52
PWD/PhJ m 22.5 9.31   4 4.65 0.414 15.5, 36.0 -0.46
PWK/PhJ m 29.5 9.76   4 4.88 0.33 16.1, 39.3 -0.04
RIIIS/J m 42.5 5.9   4 2.95 0.139 34.8, 49.0 0.76
SEA/GnJ m 34.7 6.09   4 3.05 0.175 28.7, 43.2 0.28
SJL/J m 12.0 6.44   4 3.22 0.535 8.2, 21.7 -1.11
SM/J m 31.7 13.0   4 6.52 0.412 15.8, 42.9 0.1
SWR/J m 43.8 8.37   4 4.19 0.191 32.7, 53.0 0.84
WSB/EiJ m 75.9 34.1   3 19.7 0.45 40.4, 108.0 2.81


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 43.41 4.2567 51.8542 34.9658
129X1/SvJ m 46.8075 4.2567 55.2517 38.3633
A/J m 19.945 4.2567 28.3892 11.5008
AKR/J m 32.4575 4.2567 40.9017 24.0133
BALB/cByJ m 64.48 4.2567 72.9242 56.0358
BTBR T+ Itpr3tf/J m 21.715 4.2567 30.1592 13.2708
C3H/HeJ m 26.01 4.2567 34.4542 17.5658
C57BL/6J m 11.0375 4.2567 19.4817 2.5933
C57BLKS/J m 22.5 4.2567 30.9442 14.0558
C57BR/cdJ m 19.1225 4.2567 27.5667 10.6783
C58/J m 24.96 6.0199 36.9019 13.0181
CBA/J m 27.7975 4.2567 36.2417 19.3533
CZECHII/EiJ m 17.9 4.2567 26.3442 9.4558
DBA/2J m 12.66 4.2567 21.1042 4.2158
FVB/NJ m 35.835 4.2567 44.2792 27.3908
I/LnJ m 30.6025 4.2567 39.0467 22.1583
KK/HlJ m 76.6333 4.9152 86.3838 66.8828
LG/J m 31.3325 4.2567 39.7767 22.8883
LP/J m 14.615 4.2567 23.0592 6.1708
MA/MyJ m 15.4725 4.2567 23.9167 7.0283
NOD/ShiLtJ m 11.3225 4.2567 19.7667 2.8783
NON/ShiLtJ m 27.41 4.2567 35.8542 18.9658
NZB/BlNJ m 20.9775 4.2567 29.4217 12.5333
NZO/HlLtJ m 34.96 4.2567 43.4042 26.5158
NZW/LacJ m 31.7225 4.2567 40.1667 23.2783
PERA/EiJ m 17.405 4.2567 25.8492 8.9608
PL/J m 21.6325 4.2567 30.0767 13.1883
PWD/PhJ m 22.47 4.2567 30.9142 14.0258
PWK/PhJ m 29.5275 4.2567 37.9717 21.0833
RIIIS/J m 42.5425 4.2567 50.9867 34.0983
SEA/GnJ m 34.715 4.2567 43.1592 26.2708
SJL/J m 12.0275 4.2567 20.4717 3.5833
SM/J m 31.69 4.2567 40.1342 23.2458
SWR/J m 43.845 4.2567 52.2892 35.4008
WSB/EiJ m 75.8667 4.9152 85.6172 66.1162




  GWAS USING LINEAR MIXED MODELS