Project measure / variable:   Wiltshire4   Tcells_Dox_D

ID, description, units MPD:52431   Tcells_Dox_D   T cells, percent viability   [%]  dose: 11.1 µM  
doxorubicin study
Data set, strains Wiltshire4   inbred w/CC7   35 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - T cells, percent viability dose: 11.1 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means83.6   %
Median of the strain means86.0   %
SD of the strain means± 14.9
Coefficient of variation (CV)0.179
Min–max range of strain means52.4   –   118   %
Mean sample size per strain3.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 30083.0494 884.7956 18.0121 < 0.0001
Residuals 101 4961.3483 49.1223


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 109.0 3.1   4 1.55 0.0284 107.0, 113.0 1.7
129X1/SvJ m 84.6 5.75   4 2.88 0.068 79.6, 92.9 0.06
A/J m 88.8 0.863   4 0.432 0.00972 88.0, 89.8 0.35
AKR/J m 92.6 3.93   4 1.97 0.0425 87.1, 96.4 0.6
BALB/cByJ m 95.0 4.79   4 2.39 0.0504 89.1, 99.8 0.76
BTBR T+ Itpr3tf/J m 89.9 7.79   4 3.9 0.0866 80.3, 96.8 0.42
C3H/HeJ m 80.8 4.11   4 2.05 0.0508 76.7, 86.4 -0.19
C57BL/6J m 90.3 1.16   4 0.581 0.0129 89.2, 91.9 0.45
C57BLKS/J m 77.1 3.98   4 1.99 0.0516 72.0, 80.5 -0.44
C57BR/cdJ m 94.7 1.75   4 0.875 0.0185 92.7, 96.9 0.74
C58/J m 77.0 9.21   2   6.51 0.12 70.5, 83.5 -0.44
CBA/J m 82.1 6.27   4 3.13 0.0763 74.0, 89.2 -0.1
CZECHII/EiJ m 56.8 7.09   4 3.55 0.125 46.9, 62.3 -1.8
DBA/2J m 88.9 7.97   4 3.99 0.0896 82.1, 99.1 0.35
FVB/NJ m 93.4 2.5   4 1.25 0.0268 90.0, 95.8 0.65
I/LnJ m 86.0 8.2   4 4.1 0.0954 74.9, 94.1 0.16
KK/HlJ m 88.7 0.0577   3 0.0333 0.000651 88.6, 88.7 0.34
LG/J m 53.5 15.5   4 7.75 0.29 34.6, 72.5 -2.02
LP/J m 81.0 3.48   4 1.74 0.043 78.0, 84.7 -0.18
MA/MyJ m 52.4 10.6   4 5.29 0.202 41.7, 65.0 -2.09
NOD/ShiLtJ m 84.3 1.25   4 0.623 0.0148 82.5, 85.1 0.04
NON/ShiLtJ m 68.4 9.8   4 4.9 0.143 62.0, 82.9 -1.02
NZB/BlNJ m 90.0 3.23   4 1.62 0.0359 86.3, 93.0 0.43
NZO/HlLtJ m 75.2 13.6   4 6.81 0.181 62.2, 90.6 -0.56
NZW/LacJ m 77.5 1.99   4 0.997 0.0257 74.9, 79.7 -0.41
PERA/EiJ m 61.8 12.8   4 6.39 0.207 46.3, 75.3 -1.46
PL/J m 68.9 7.58   4 3.79 0.11 61.5, 76.7 -0.99
PWD/PhJ m 98.8 1.26   4 0.631 0.0128 97.2, 100.0 1.02
PWK/PhJ m 69.2 9.27   4 4.64 0.134 55.5, 76.0 -0.97
RIIIS/J m 96.3 4.66   4 2.33 0.0484 92.5, 103.0 0.85
SEA/GnJ m 95.3 0.275   4 0.138 0.00289 95.1, 95.7 0.78
SJL/J m 92.5 2.99   4 1.5 0.0324 89.5, 95.2 0.59
SM/J m 67.3 10.1   4 5.05 0.15 57.0, 77.8 -1.09
SWR/J m 118.0 3.6   4 1.8 0.0304 114.0, 122.0 2.3
WSB/EiJ m 101.0 12.4   3 7.18 0.124 86.9, 111.0 1.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 109.3725 3.5044 116.3242 102.4208
129X1/SvJ m 84.575 3.5044 91.5267 77.6233
A/J m 88.805 3.5044 95.7567 81.8533
AKR/J m 92.6075 3.5044 99.5592 85.6558
BALB/cByJ m 95.0475 3.5044 101.9992 88.0958
BTBR T+ Itpr3tf/J m 89.9425 3.5044 96.8942 82.9908
C3H/HeJ m 80.815 3.5044 87.7667 73.8633
C57BL/6J m 90.3325 3.5044 97.2842 83.3808
C57BLKS/J m 77.0925 3.5044 84.0442 70.1408
C57BR/cdJ m 94.7375 3.5044 101.6892 87.7858
C58/J m 76.96 4.9559 86.7912 67.1288
CBA/J m 82.09 3.5044 89.0417 75.1383
CZECHII/EiJ m 56.84 3.5044 63.7917 49.8883
DBA/2J m 88.9175 3.5044 95.8692 81.9658
FVB/NJ m 93.4225 3.5044 100.3742 86.4708
I/LnJ m 85.9925 3.5044 92.9442 79.0408
KK/HlJ m 88.7067 4.0465 96.7338 80.6795
LG/J m 53.4675 3.5044 60.4192 46.5158
LP/J m 80.9625 3.5044 87.9142 74.0108
MA/MyJ m 52.42 3.5044 59.3717 45.4683
NOD/ShiLtJ m 84.275 3.5044 91.2267 77.3233
NON/ShiLtJ m 68.39 3.5044 75.3417 61.4383
NZB/BlNJ m 90.05 3.5044 97.0017 83.0983
NZO/HlLtJ m 75.235 3.5044 82.1867 68.2833
NZW/LacJ m 77.4775 3.5044 84.4292 70.5258
PERA/EiJ m 61.755 3.5044 68.7067 54.8033
PL/J m 68.905 3.5044 75.8567 61.9533
PWD/PhJ m 98.8 3.5044 105.7517 91.8483
PWK/PhJ m 69.1775 3.5044 76.1292 62.2258
RIIIS/J m 96.33 3.5044 103.2817 89.3783
SEA/GnJ m 95.3075 3.5044 102.2592 88.3558
SJL/J m 92.4975 3.5044 99.4492 85.5458
SM/J m 67.32 3.5044 74.2717 60.3683
SWR/J m 118.3325 3.5044 125.2842 111.3808
WSB/EiJ m 100.5833 4.0465 108.6105 92.5562




  GWAS USING LINEAR MIXED MODELS