Project measure / variable:   Wiltshire4   Tcells_Sel_D

ID, description, units MPD:52471   Tcells_Sel_D   T cells, percent viability   [%]  dose: 11.1 µM  
selumetinib study
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - T cells, percent viability dose: 11.1 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested34 strains
Mean of the strain means99.6   %
Median of the strain means99.5   %
SD of the strain means± 2.95
Coefficient of variation (CV)0.0296
Min–max range of strain means94.7   –   111   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 1178.0101 35.6973 2.6212 0.0001
Residuals 99 1348.2286 13.6185


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 105.0 1.25   4 0.625 0.0118 104.0, 107.0 1.85
129X1/SvJ m 98.3 6.92   4 3.46 0.0704 90.4, 107.0 -0.43
A/J m 99.9 1.84   4 0.922 0.0185 97.6, 102.0 0.12
AKR/J m 100.0 0.887   4 0.443 0.00883 99.1, 101.0 0.15
BALB/cByJ m 99.8 1.13   4 0.566 0.0113 98.3, 101.0 0.08
BTBR T+ Itpr3tf/J m 96.3 2.05   4 1.03 0.0213 94.0, 98.6 -1.1
BUB/BnJ m 99.2 1.23   4 0.615 0.0124 97.6, 100.0 -0.12
C3H/HeJ m 99.3 0.676   4 0.338 0.0068 98.7, 100.0 -0.09
C57BL/6J m 99.6 0.146   4 0.0731 0.00147 99.5, 99.8 0.02
C57BLKS/J m 99.8 2.02   4 1.01 0.0203 97.5, 102.0 0.08
C58/J m 96.3 0.311   2   0.22 0.00323 96.1, 96.5 -1.1
CBA/J m 99.6 4.95   4 2.47 0.0497 96.6, 107.0 0.02
CZECHII/EiJ m 99.7 8.12   4 4.06 0.0814 89.5, 109.0 0.05
DBA/2J m 96.5 6.8   4 3.4 0.0705 91.4, 106.0 -1.04
FVB/NJ m 100.0 1.43   4 0.713 0.0142 98.0, 101.0 0.15
I/LnJ m 100.0 2.03   4 1.02 0.0203 97.4, 102.0 0.15
KK/HlJ m 94.7 1.86   4 0.929 0.0196 91.9, 95.7 -1.65
LG/J m 111.0 5.74   4 2.87 0.0515 108.0, 120.0 3.88
LP/J m 99.2 2.17   4 1.09 0.0219 97.0, 101.0 -0.12
MA/MyJ m 97.9 1.06   4 0.531 0.0108 96.6, 99.0 -0.56
NOD/ShiLtJ m 99.3 1.38   4 0.69 0.0139 97.5, 101.0 -0.09
NON/ShiLtJ m 98.9 4.12   4 2.06 0.0416 94.6, 103.0 -0.22
NZB/BlNJ m 100.0 0.612   4 0.306 0.00612 99.4, 101.0 0.15
NZO/HlLtJ m 95.0 5.7   4 2.85 0.06 87.1, 101.0 -1.54
NZW/LacJ m 95.3 1.48   4 0.742 0.0156 93.1, 96.3 -1.44
PERA/EiJ m 97.9 3.07   4 1.53 0.0313 93.7, 101.0 -0.56
PL/J m 99.4 2.79   4 1.39 0.028 95.7, 102.0 -0.05
PWD/PhJ m 99.5 2.8   4 1.4 0.0282 95.9, 102.0 -0.02
PWK/PhJ m 102.0 2.57   4 1.29 0.0252 98.4, 104.0 0.83
RIIIS/J m 102.0 4.43   4 2.22 0.0435 96.9, 106.0 0.83
SEA/GnJ m 99.4 3.39   4 1.7 0.0341 95.2, 103.0 -0.05
SJL/J m 102.0 1.86   4 0.931 0.0183 100.0, 104.0 0.83
SM/J m 102.0 2.96   4 1.48 0.029 97.4, 103.0 0.83
WSB/EiJ m 100.0 10.3   3 5.93 0.102 90.1, 111.0 0.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 105.485 1.8452 109.1462 101.8238
129X1/SvJ m 98.2925 1.8452 101.9537 94.6313
A/J m 99.8925 1.8452 103.5537 96.2313
AKR/J m 100.43 1.8452 104.0912 96.7688
BALB/cByJ m 99.8225 1.8452 103.4837 96.1613
BTBR T+ Itpr3tf/J m 96.285 1.8452 99.9462 92.6238
BUB/BnJ m 99.23 1.8452 102.8912 95.5688
C3H/HeJ m 99.34 1.8452 103.0012 95.6788
C57BL/6J m 99.6425 1.8452 103.3037 95.9813
C57BLKS/J m 99.8225 1.8452 103.4837 96.1613
C58/J m 96.31 2.6095 101.4877 91.1323
CBA/J m 99.6175 1.8452 103.2787 95.9563
CZECHII/EiJ m 99.7325 1.8452 103.3937 96.0713
DBA/2J m 96.45 1.8452 100.1112 92.7888
FVB/NJ m 100.155 1.8452 103.8162 96.4938
I/LnJ m 100.3075 1.8452 103.9687 96.6463
KK/HlJ m 94.665 1.8452 98.3262 91.0038
LG/J m 111.2975 1.8452 114.9587 107.6363
LP/J m 99.2175 1.8452 102.8787 95.5563
MA/MyJ m 97.8975 1.8452 101.5587 94.2363
NOD/ShiLtJ m 99.27 1.8452 102.9312 95.6088
NON/ShiLtJ m 98.86 1.8452 102.5212 95.1988
NZB/BlNJ m 99.9725 1.8452 103.6337 96.3113
NZO/HlLtJ m 94.99 1.8452 98.6512 91.3288
NZW/LacJ m 95.2775 1.8452 98.9387 91.6163
PERA/EiJ m 97.935 1.8452 101.5962 94.2738
PL/J m 99.385 1.8452 103.0462 95.7238
PWD/PhJ m 99.45 1.8452 103.1112 95.7888
PWK/PhJ m 102.1675 1.8452 105.8287 98.5063
RIIIS/J m 101.845 1.8452 105.5062 98.1838
SEA/GnJ m 99.39 1.8452 103.0512 95.7288
SJL/J m 101.8675 1.8452 105.5287 98.2063
SM/J m 101.8525 1.8452 105.5137 98.1913
WSB/EiJ m 100.2333 2.1306 104.4609 96.0057




  GWAS USING LINEAR MIXED MODELS