Phenotype measure:   Wiltshire4   monocytes_Sel_D

ID, description, units MPD:52477   monocytes_Sel_D   monocytes, percent viability   [%]  dose: 11.1 µM
selumetinib study
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Wiltshire4 - monocytes, percent viability dose: 11.1 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested34 strains
Mean of the strain means97.5   %
Median of the strain means98.8   %
SD of the strain means± 9.39
Coefficient of variation (CV)0.0963
Min–max range of strain means70.8   –   114   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 10713.9902 324.6664 1.797 0.0142
Residuals 99 17886.6586 180.6733


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 106.0 24.6   4 12.3 0.231 76.8, 129.0 0.91
129X1/SvJ m 95.9 4.21   4 2.1 0.0439 93.2, 102.0 -0.17
A/J m 103.0 5.1   4 2.55 0.0497 96.9, 109.0 0.59
AKR/J m 101.0 2.06   4 1.03 0.0204 98.1, 103.0 0.37
BALB/cByJ m 104.0 6.28   4 3.14 0.0605 98.8, 113.0 0.69
BTBR T+ Itpr3tf/J m 70.8 19.6   4 9.78 0.276 45.1, 89.3 -2.84
BUB/BnJ m 95.6 4.34   4 2.17 0.0454 89.1, 98.2 -0.2
C3H/HeJ m 99.5 2.71   4 1.36 0.0273 96.1, 102.0 0.21
C57BL/6J m 101.0 2.2   4 1.1 0.0218 98.6, 103.0 0.37
C57BLKS/J m 93.9 11.3   4 5.66 0.121 85.7, 110.0 -0.38
C58/J m 76.0 1.08   2   0.765 0.0142 75.2, 76.8 -2.29
CBA/J m 91.8 16.4   4 8.19 0.179 82.9, 116.0 -0.61
CZECHII/EiJ m 105.0 11.7   4 5.86 0.112 91.3, 119.0 0.8
DBA/2J m 97.8 24.0   4 12.0 0.245 77.2, 132.0 0.03
FVB/NJ m 102.0 6.23   4 3.12 0.0608 93.4, 107.0 0.48
I/LnJ m 103.0 4.44   4 2.22 0.0432 96.4, 107.0 0.59
KK/HlJ m 90.8 2.71   4 1.35 0.0298 86.8, 92.9 -0.71
LG/J m 101.0 9.39   4 4.69 0.0925 93.0, 114.0 0.37
LP/J m 103.0 3.55   4 1.78 0.0346 99.0, 107.0 0.59
MA/MyJ m 96.4 1.91   4 0.953 0.0198 94.0, 98.0 -0.12
NOD/ShiLtJ m 93.2 10.9   4 5.43 0.117 79.4, 102.0 -0.46
NON/ShiLtJ m 81.6 13.2   4 6.6 0.162 70.3, 99.2 -1.69
NZB/BlNJ m 101.0 1.91   4 0.956 0.0189 98.4, 102.0 0.37
NZO/HlLtJ m 93.6 7.18   4 3.59 0.0767 83.6, 100.0 -0.42
NZW/LacJ m 85.4 5.35   4 2.67 0.0626 77.8, 89.7 -1.29
PERA/EiJ m 113.0 12.9   4 6.44 0.114 97.6, 127.0 1.65
PL/J m 98.0 5.7   4 2.85 0.0582 90.7, 103.0 0.05
PWD/PhJ m 114.0 12.7   4 6.34 0.111 104.0, 132.0 1.76
PWK/PhJ m 101.0 5.3   4 2.65 0.0522 95.2, 106.0 0.37
RIIIS/J m 113.0 25.5   4 12.8 0.226 87.5, 139.0 1.65
SEA/GnJ m 92.9 11.4   4 5.68 0.122 77.0, 104.0 -0.49
SJL/J m 97.4 12.1   4 6.03 0.124 85.5, 113.0 -0.01
SM/J m 103.0 2.3   4 1.15 0.0223 100.0, 106.0 0.59
WSB/EiJ m 90.4 53.1   3 30.7 0.587 35.6, 142.0 -0.76


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 106.4275 6.7207 119.7629 93.0921
129X1/SvJ m 95.885 6.7207 109.2204 82.5496
A/J m 102.5475 6.7207 115.8829 89.2121
AKR/J m 101.1025 6.7207 114.4379 87.7671
BALB/cByJ m 103.8725 6.7207 117.2079 90.5371
BTBR T+ Itpr3tf/J m 70.7825 6.7207 84.1179 57.4471
BUB/BnJ m 95.6 6.7207 108.9354 82.2646
C3H/HeJ m 99.4875 6.7207 112.8229 86.1521
C57BL/6J m 100.9125 6.7207 114.2479 87.5771
C57BLKS/J m 93.8625 6.7207 107.1979 80.5271
C58/J m 75.995 9.5046 94.8541 57.1359
CBA/J m 91.775 6.7207 105.1104 78.4396
CZECHII/EiJ m 104.8275 6.7207 118.1629 91.4921
DBA/2J m 97.815 6.7207 111.1504 84.4796
FVB/NJ m 102.5 6.7207 115.8354 89.1646
I/LnJ m 102.7725 6.7207 116.1079 89.4371
KK/HlJ m 90.8375 6.7207 104.1729 77.5021
LG/J m 101.445 6.7207 114.7804 88.1096
LP/J m 102.6 6.7207 115.9354 89.2646
MA/MyJ m 96.3775 6.7207 109.7129 83.0421
NOD/ShiLtJ m 93.1825 6.7207 106.5179 79.8471
NON/ShiLtJ m 81.6025 6.7207 94.9379 68.2671
NZB/BlNJ m 101.2525 6.7207 114.5879 87.9171
NZO/HlLtJ m 93.56 6.7207 106.8954 80.2246
NZW/LacJ m 85.4275 6.7207 98.7629 72.0921
PERA/EiJ m 112.98 6.7207 126.3154 99.6446
PL/J m 98.0125 6.7207 111.3479 84.6771
PWD/PhJ m 114.4325 6.7207 127.7679 101.0971
PWK/PhJ m 101.47 6.7207 114.8054 88.1346
RIIIS/J m 112.9825 6.7207 126.3179 99.6471
SEA/GnJ m 92.895 6.7207 106.2304 79.5596
SJL/J m 97.375 6.7207 110.7104 84.0396
SM/J m 103.0825 6.7207 116.4179 89.7471
WSB/EiJ m 90.4333 7.7604 105.8317 75.0349




  GWAS USING LINEAR MIXED MODELS