Project measure / variable:   Wiltshire4   Tcells_Sel_B

ID, description, units MPD:52469   Tcells_Sel_B   T cells, percent viability   [%]  dose: 0.137 µM  
selumetinib study
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - T cells, percent viability dose: 0.137 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested34 strains
Mean of the strain means99.8   %
Median of the strain means99.8   %
SD of the strain means± 2.96
Coefficient of variation (CV)0.0297
Min–max range of strain means94.6   –   112   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 1106.3079 33.5245 3.076 < 0.0001
Residuals 99 1078.9743 10.8987


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 104.0 2.29   4 1.15 0.022 102.0, 108.0 1.43
129X1/SvJ m 101.0 5.01   4 2.5 0.0495 94.8, 107.0 0.42
A/J m 98.6 1.6   4 0.799 0.0162 96.5, 100.0 -0.39
AKR/J m 100.0 0.729   4 0.364 0.00726 99.3, 101.0 0.08
BALB/cByJ m 100.0 0.557   4 0.278 0.00555 99.5, 101.0 0.08
BTBR T+ Itpr3tf/J m 98.5 1.25   4 0.623 0.0126 97.5, 100.0 -0.42
BUB/BnJ m 99.0 1.5   4 0.752 0.0152 97.1, 101.0 -0.25
C3H/HeJ m 98.6 0.622   4 0.311 0.00631 97.8, 99.4 -0.39
C57BL/6J m 100.0 0.682   4 0.341 0.00682 99.0, 100.0 0.08
C57BLKS/J m 97.7 5.18   4 2.59 0.053 92.4, 103.0 -0.69
C58/J m 94.6 2.07   2   1.47 0.0219 93.2, 96.1 -1.74
CBA/J m 100.0 2.62   4 1.31 0.0262 97.9, 104.0 0.08
CZECHII/EiJ m 103.0 4.76   4 2.38 0.0463 96.0, 106.0 1.1
DBA/2J m 98.8 4.36   4 2.18 0.0442 95.0, 105.0 -0.32
FVB/NJ m 99.7 1.02   4 0.512 0.0103 99.1, 101.0 -0.02
I/LnJ m 101.0 1.4   4 0.701 0.0139 98.7, 102.0 0.42
KK/HlJ m 96.0 3.87   4 1.93 0.0403 92.5, 100.0 -1.27
LG/J m 112.0 4.61   4 2.31 0.0412 108.0, 118.0 4.13
LP/J m 99.5 0.427   4 0.214 0.0043 99.1, 99.9 -0.09
MA/MyJ m 100.0 1.33   4 0.664 0.0133 98.0, 101.0 0.08
NOD/ShiLtJ m 98.0 5.13   4 2.56 0.0523 92.1, 104.0 -0.59
NON/ShiLtJ m 98.9 3.37   4 1.68 0.034 95.6, 104.0 -0.29
NZB/BlNJ m 100.0 1.09   4 0.543 0.0108 98.7, 101.0 0.08
NZO/HlLtJ m 95.5 2.33   4 1.16 0.0244 92.4, 97.6 -1.44
NZW/LacJ m 95.6 2.98   4 1.49 0.0312 92.5, 99.6 -1.4
PERA/EiJ m 98.8 5.67   4 2.83 0.0574 92.4, 106.0 -0.32
PL/J m 100.0 1.88   4 0.938 0.0187 97.5, 102.0 0.08
PWD/PhJ m 98.6 2.97   4 1.49 0.0302 94.2, 101.0 -0.39
PWK/PhJ m 99.6 3.58   4 1.79 0.036 95.5, 104.0 -0.05
RIIIS/J m 99.8 2.9   4 1.45 0.029 97.0, 104.0 0.02
SEA/GnJ m 100.0 1.51   4 0.755 0.0151 98.0, 101.0 0.08
SJL/J m 102.0 2.21   4 1.1 0.0217 99.9, 105.0 0.76
SM/J m 103.0 0.577   4 0.288 0.00559 102.0, 104.0 1.1
WSB/EiJ m 99.8 10.7   3 6.2 0.108 87.6, 108.0 0.02


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 104.22 1.6507 107.4953 100.9447
129X1/SvJ m 101.1375 1.6507 104.4128 97.8622
A/J m 98.605 1.6507 101.8803 95.3297
AKR/J m 100.405 1.6507 103.6803 97.1297
BALB/cByJ m 100.2525 1.6507 103.5278 96.9772
BTBR T+ Itpr3tf/J m 98.485 1.6507 101.7603 95.2097
BUB/BnJ m 98.995 1.6507 102.2703 95.7197
C3H/HeJ m 98.61 1.6507 101.8853 95.3347
C57BL/6J m 100.0525 1.6507 103.3278 96.7772
C57BLKS/J m 97.74 1.6507 101.0153 94.4647
C58/J m 94.625 2.3344 99.2569 89.9931
CBA/J m 100.1375 1.6507 103.4128 96.8622
CZECHII/EiJ m 102.9175 1.6507 106.1928 99.6422
DBA/2J m 98.7875 1.6507 102.0628 95.5122
FVB/NJ m 99.67 1.6507 102.9453 96.3947
I/LnJ m 100.6925 1.6507 103.9678 97.4172
KK/HlJ m 96.0175 1.6507 99.2928 92.7422
LG/J m 111.9425 1.6507 115.2178 108.6672
LP/J m 99.4525 1.6507 102.7278 96.1772
MA/MyJ m 100.025 1.6507 103.3003 96.7497
NOD/ShiLtJ m 97.9825 1.6507 101.2578 94.7072
NON/ShiLtJ m 98.8925 1.6507 102.1678 95.6172
NZB/BlNJ m 100.3525 1.6507 103.6278 97.0772
NZO/HlLtJ m 95.53 1.6507 98.8053 92.2547
NZW/LacJ m 95.58 1.6507 98.8553 92.3047
PERA/EiJ m 98.8175 1.6507 102.0928 95.5422
PL/J m 100.23 1.6507 103.5053 96.9547
PWD/PhJ m 98.5775 1.6507 101.8528 95.3022
PWK/PhJ m 99.645 1.6507 102.9203 96.3697
RIIIS/J m 99.7825 1.6507 103.0578 96.5072
SEA/GnJ m 100.2375 1.6507 103.5128 96.9622
SJL/J m 101.785 1.6507 105.0603 98.5097
SM/J m 103.13 1.6507 106.4053 99.8547
WSB/EiJ m 99.8433 1.906 103.6253 96.0614




  GWAS USING LINEAR MIXED MODELS