Project measure / variable:   Wiltshire4   Bcells_BEZ_C

ID, description, units MPD:52404   Bcells_BEZ_C   B cells, percent viability   [%]  dose: 1.235 µM  
BEZ235 study
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - B cells, percent viability dose: 1.235 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested34 strains
Mean of the strain means90.1   %
Median of the strain means92.8   %
SD of the strain means± 18.4
Coefficient of variation (CV)0.204
Min–max range of strain means37.6   –   132   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 43446.2322 1316.5525 2.6172 0.0001
Residuals 99 49800.9984 503.0404


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 118.0 9.39   4 4.7 0.0799 109.0, 127.0 1.52
129X1/SvJ m 89.9 7.58   4 3.79 0.0843 80.3, 97.0 -0.01
A/J m 89.2 2.34   4 1.17 0.0262 86.2, 91.9 -0.05
AKR/J m 99.9 0.853   4 0.427 0.00854 98.8, 101.0 0.53
BALB/cByJ m 100.0 8.01   4 4.01 0.0799 88.3, 105.0 0.54
BTBR T+ Itpr3tf/J m 88.4 16.2   4 8.11 0.184 73.7, 107.0 -0.09
BUB/BnJ m 92.9 13.6   4 6.81 0.147 80.5, 112.0 0.15
C3H/HeJ m 81.1 9.33   4 4.67 0.115 71.6, 93.8 -0.49
C57BL/6J m 93.5 5.88   4 2.94 0.0629 85.3, 98.4 0.18
C57BLKS/J m 104.0 13.7   4 6.87 0.133 89.5, 120.0 0.75
C58/J m 73.3 38.7   2   27.4 0.528 46.0, 101.0 -0.92
CBA/J m 108.0 43.1   4 21.5 0.4 67.8, 166.0 0.97
CZECHII/EiJ m 105.0 56.2   4 28.1 0.536 66.1, 188.0 0.81
DBA/2J m 81.6 31.5   4 15.8 0.386 51.7, 110.0 -0.46
FVB/NJ m 99.6 14.5   4 7.23 0.145 86.1, 120.0 0.52
I/LnJ m 93.2 11.0   4 5.52 0.118 80.8, 103.0 0.17
KK/HlJ m 92.3 6.23   4 3.11 0.0675 87.3, 101.0 0.12
LG/J m 86.0 35.1   4 17.6 0.408 43.0, 129.0 -0.23
LP/J m 84.2 6.41   4 3.21 0.0762 75.3, 90.2 -0.32
MA/MyJ m 91.2 6.82   4 3.41 0.0748 84.9, 101.0 0.06
NOD/ShiLtJ m 51.8 19.3   4 9.66 0.373 23.2, 65.5 -2.09
NON/ShiLtJ m 96.5 16.9   4 8.47 0.175 80.1, 112.0 0.35
NZB/BlNJ m 97.6 3.14   4 1.57 0.0321 93.7, 101.0 0.41
NZO/HlLtJ m 79.9 32.4   4 16.2 0.406 36.4, 106.0 -0.56
NZW/LacJ m 49.5 4.81   4 2.41 0.0972 45.6, 56.4 -2.21
PERA/EiJ m 132.0 56.1   4 28.0 0.425 69.3, 206.0 2.28
PL/J m 81.7 30.1   4 15.0 0.368 44.0, 115.0 -0.46
PWD/PhJ m 102.0 18.5   4 9.23 0.181 77.2, 122.0 0.65
PWK/PhJ m 92.7 9.37   4 4.68 0.101 78.8, 98.8 0.14
RIIIS/J m 98.3 1.99   4 0.997 0.0203 96.7, 101.0 0.44
SEA/GnJ m 71.8 3.2   4 1.6 0.0445 68.4, 76.1 -1.0
SJL/J m 92.9 33.1   4 16.5 0.356 60.0, 124.0 0.15
SM/J m 37.6 2.47   4 1.24 0.0657 34.5, 40.5 -2.86
WSB/EiJ m 109.0 11.8   3 6.82 0.108 102.0, 123.0 1.03


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 117.5225 11.2143 139.7741 95.2709
129X1/SvJ m 89.8525 11.2143 112.1041 67.6009
A/J m 89.1875 11.2143 111.4391 66.9359
AKR/J m 99.925 11.2143 122.1766 77.6734
BALB/cByJ m 100.305 11.2143 122.5566 78.0534
BTBR T+ Itpr3tf/J m 88.39 11.2143 110.6416 66.1384
BUB/BnJ m 92.8525 11.2143 115.1041 70.6009
C3H/HeJ m 81.09 11.2143 103.3416 58.8384
C57BL/6J m 93.5225 11.2143 115.7741 71.2709
C57BLKS/J m 103.525 11.2143 125.7766 81.2734
C58/J m 73.335 15.8594 104.8035 41.8665
CBA/J m 107.68 11.2143 129.9316 85.4284
CZECHII/EiJ m 104.755 11.2143 127.0066 82.5034
DBA/2J m 81.6475 11.2143 103.8991 59.3959
FVB/NJ m 99.555 11.2143 121.8066 77.3034
I/LnJ m 93.2225 11.2143 115.4741 70.9709
KK/HlJ m 92.3425 11.2143 114.5941 70.0909
LG/J m 86.03 11.2143 108.2816 63.7784
LP/J m 84.175 11.2143 106.4266 61.9234
MA/MyJ m 91.1725 11.2143 113.4241 68.9209
NOD/ShiLtJ m 51.83 11.2143 74.0816 29.5784
NON/ShiLtJ m 96.5475 11.2143 118.7991 74.2959
NZB/BlNJ m 97.6325 11.2143 119.8841 75.3809
NZO/HlLtJ m 79.855 11.2143 102.1066 57.6034
NZW/LacJ m 49.4775 11.2143 71.7291 27.2259
PERA/EiJ m 131.8125 11.2143 154.0641 109.5609
PL/J m 81.6625 11.2143 103.9141 59.4109
PWD/PhJ m 102.2125 11.2143 124.4641 79.9609
PWK/PhJ m 92.745 11.2143 114.9966 70.4934
RIIIS/J m 98.3 11.2143 120.5516 76.0484
SEA/GnJ m 71.8375 11.2143 94.0891 49.5859
SJL/J m 92.87 11.2143 115.1216 70.6184
SM/J m 37.575 11.2143 59.8266 15.3234
WSB/EiJ m 109.4867 12.9491 135.1806 83.7928




  GWAS USING LINEAR MIXED MODELS