Project measure / variable:   Wiltshire4   Bcells_Dox_D

ID, description, units MPD:52425   Bcells_Dox_D   B cells, percent viability   [%]  dose: 11.1 µM  
doxorubicin study
Data set, strains Wiltshire4   inbred w/CC7   35 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - B cells, percent viability dose: 11.1 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means18.4   %
Median of the strain means5.48   %
SD of the strain means± 24.6
Coefficient of variation (CV)1.33
Min–max range of strain means0.993   –   94.0   %
Mean sample size per strain3.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 75724.9219 2227.2036 21.4385 < 0.0001
Residuals 101 10492.7077 103.8882


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 84.6 28.7   4 14.3 0.339 45.2, 110.0 2.69
129X1/SvJ m 33.6 6.11   4 3.05 0.182 24.8, 38.5 0.62
A/J m 31.5 6.96   4 3.48 0.221 25.3, 38.7 0.53
AKR/J m 27.0 5.11   4 2.55 0.19 20.6, 31.7 0.35
BALB/cByJ m 67.9 7.28   4 3.64 0.107 59.3, 76.5 2.01
BTBR T+ Itpr3tf/J m 8.45 7.19   4 3.6 0.851 3.83, 19.2 -0.41
C3H/HeJ m 5.23 1.8   4 0.901 0.345 3.14, 7.53 -0.54
C57BL/6J m 2.13 1.61   4 0.807 0.756 0.4, 4.02 -0.66
C57BLKS/J m 3.09 1.32   4 0.661 0.427 1.57, 4.77 -0.63
C57BR/cdJ m 4.41 3.0   4 1.5 0.68 2.46, 8.88 -0.57
C58/J m 5.48 2.38   2   1.69 0.434 3.8, 7.17 -0.53
CBA/J m 7.75 2.59   4 1.29 0.334 4.58, 10.8 -0.44
CZECHII/EiJ m 2.58 0.885   4 0.443 0.343 1.66, 3.73 -0.65
DBA/2J m 5.71 4.79   4 2.4 0.839 1.29, 11.8 -0.52
FVB/NJ m 19.2 6.36   4 3.18 0.332 11.1, 26.1 0.03
I/LnJ m 9.56 9.39   4 4.7 0.982 1.5, 20.0 -0.36
KK/HlJ m 31.3 6.14   3 3.54 0.196 26.0, 38.0 0.52
LG/J m 1.31 0.932   4 0.466 0.711 0.26, 2.48 -0.7
LP/J m 4.01 4.68   4 2.34 1.17 1.3, 11.0 -0.59
MA/MyJ m 0.993 0.116   4 0.0579 0.117 0.83, 1.1 -0.71
NOD/ShiLtJ m 4.5 1.19   4 0.593 0.264 3.16, 5.7 -0.57
NON/ShiLtJ m 10.8 3.83   4 1.92 0.353 7.32, 15.2 -0.31
NZB/BlNJ m 1.8 0.964   4 0.482 0.537 0.69, 2.79 -0.68
NZO/HlLtJ m 1.29 0.996   4 0.498 0.772 -0.7
NZW/LacJ m 2.11 1.23   4 0.613 0.581 0.61, 3.53 -0.67
PERA/EiJ m 5.21 1.73   4 0.864 0.332 3.37, 7.42 -0.54
PL/J m 4.54 2.94   4 1.47 0.647 1.22, 8.34 -0.57
PWD/PhJ m 16.5 3.31   4 1.65 0.201 12.9, 20.9 -0.08
PWK/PhJ m 59.9 8.86   4 4.43 0.148 49.5, 70.0 1.69
RIIIS/J m 5.08 1.06   4 0.532 0.209 3.79, 6.21 -0.54
SEA/GnJ m 38.0 9.19   4 4.6 0.242 26.1, 48.3 0.8
SJL/J m 1.91 1.55   4 0.773 0.811 0.45, 3.31 -0.67
SM/J m 2.99 0.779   4 0.39 0.261 2.0, 3.75 -0.63
SWR/J m 41.1 42.6   4 21.3 1.04 17.0, 105.0 0.92
WSB/EiJ m 94.0 17.5   3 10.1 0.186 74.2, 108.0 3.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 84.605 5.0963 94.7146 74.4954
129X1/SvJ m 33.5775 5.0963 43.6871 23.4679
A/J m 31.49 5.0963 41.5996 21.3804
AKR/J m 26.955 5.0963 37.0646 16.8454
BALB/cByJ m 67.89 5.0963 77.9996 57.7804
BTBR T+ Itpr3tf/J m 8.4525 5.0963 18.5621 0.0
C3H/HeJ m 5.2275 5.0963 15.3371 0.0
C57BL/6J m 2.135 5.0963 12.2446 0.0
C57BLKS/J m 3.095 5.0963 13.2046 0.0
C57BR/cdJ m 4.41 5.0963 14.5196 0.0
C58/J m 5.485 7.2072 19.7822 0.0
CBA/J m 7.75 5.0963 17.8596 0.0
CZECHII/EiJ m 2.5825 5.0963 12.6921 0.0
DBA/2J m 5.7125 5.0963 15.8221 0.0
FVB/NJ m 19.155 5.0963 29.2646 9.0454
I/LnJ m 9.5625 5.0963 19.6721 0.0
KK/HlJ m 31.2867 5.8847 42.9603 19.6131
LG/J m 1.31 5.0963 11.4196 0.0
LP/J m 4.0125 5.0963 14.1221 0.0
MA/MyJ m 0.9925 5.0963 11.1021 0.0
NOD/ShiLtJ m 4.495 5.0963 14.6046 0.0
NON/ShiLtJ m 10.8425 5.0963 20.9521 0.7329
NZB/BlNJ m 1.7975 5.0963 11.9071 0.0
NZO/HlLtJ m 1.29 5.0963 11.3996 0.0
NZW/LacJ m 2.11 5.0963 12.2196 0.0
PERA/EiJ m 5.205 5.0963 15.3146 0.0
PL/J m 4.5425 5.0963 14.6521 0.0
PWD/PhJ m 16.4925 5.0963 26.6021 6.3829
PWK/PhJ m 59.9 5.0963 70.0096 49.7904
RIIIS/J m 5.085 5.0963 15.1946 0.0
SEA/GnJ m 38.05 5.0963 48.1596 27.9404
SJL/J m 1.905 5.0963 12.0146 0.0
SM/J m 2.99 5.0963 13.0996 0.0
SWR/J m 41.135 5.0963 51.2446 31.0254
WSB/EiJ m 93.9733 5.8847 105.6469 82.2997




  GWAS USING LINEAR MIXED MODELS