Project measure / variable:   Wiltshire4   monocytes_Dox_E

ID, description, units MPD:52438   monocytes_Dox_E   monocytes, percent viability   [%]  dose: 100 µM  
doxorubicin study
Data set, strains Wiltshire4   inbred w/CC7   35 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - monocytes, percent viability dose: 100 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means28.4   %
Median of the strain means22.2   %
SD of the strain means± 18.4
Coefficient of variation (CV)0.647
Min–max range of strain means5.14   –   66.6   %
Mean sample size per strain3.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 44049.509 1334.8336 9.9929 < 0.0001
Residuals 99 13224.2222 133.578


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 8.55 3.11   4 1.55 0.363 5.34, 11.6 -1.08
129X1/SvJ m 42.9 15.4   4 7.69 0.359 24.1, 56.9 0.79
A/J m 16.4 5.7   4 2.85 0.347 10.7, 24.0 -0.65
AKR/J m 26.8 8.93   4 4.47 0.333 20.3, 40.0 -0.09
BALB/cByJ m 57.2 15.9   4 7.97 0.279 35.1, 71.4 1.57
BTBR T+ Itpr3tf/J m 8.0 2.89   4 1.44 0.361 5.38, 11.5 -1.11
C3H/HeJ m 21.8 8.14   4 4.07 0.373 15.4, 33.5 -0.36
C57BL/6J m 17.7 7.4   4 3.7 0.419 11.0, 28.2 -0.58
C57BLKS/J m 29.1 8.47   4 4.23 0.291 23.1, 41.6 0.04
C57BR/cdJ m 35.3 10.5   4 5.25 0.297 21.5, 46.0 0.38
C58/J m 13.3 0.247   2   0.175 0.0186 13.2, 13.5 -0.82
CBA/J m 47.3 18.7   4 9.36 0.396 21.0, 63.5 1.03
CZECHII/EiJ m 16.1 4.2   4 2.1 0.261 10.4, 20.4 -0.67
DBA/2J m 66.2 15.8   4 7.88 0.238 44.6, 79.4 2.06
FVB/NJ m 25.8 3.87   4 1.93 0.15 22.0, 29.9 -0.14
I/LnJ m 18.4 0.0   1   0.0 0.0 18.4, 18.4 -0.54
KK/HlJ m 15.1 15.4   4 7.69 1.02 -0.72
LG/J m 20.7 4.86   4 2.43 0.235 15.7, 26.8 -0.42
LP/J m 10.1 3.14   4 1.57 0.311 6.79, 14.3 -1.0
MA/MyJ m 12.9 5.0   4 2.5 0.389 8.2, 19.9 -0.84
NOD/ShiLtJ m 5.14 3.57   4 1.78 0.694 -1.27
NON/ShiLtJ m 15.7 4.22   4 2.11 0.269 9.62, 19.4 -0.69
NZB/BlNJ m 49.8 29.8   4 14.9 0.597 15.8, 83.4 1.17
NZO/HlLtJ m 24.6 4.27   4 2.14 0.174 18.8, 28.6 -0.21
NZW/LacJ m 29.2 6.96   4 3.48 0.238 22.4, 38.6 0.05
PERA/EiJ m 12.1 8.18   4 4.09 0.677 5.3, 22.9 -0.89
PL/J m 47.7 14.6   4 7.28 0.306 28.6, 62.8 1.05
PWD/PhJ m 64.7 19.1   4 9.57 0.296 49.6, 90.7 1.98
PWK/PhJ m 13.5 5.14   4 2.57 0.381 7.16, 19.4 -0.81
RIIIS/J m 8.56 8.05   4 4.03 0.941 2.99, 20.1 -1.08
SEA/GnJ m 30.3 10.1   4 5.07 0.334 21.3, 42.9 0.11
SJL/J m 66.6 16.4   4 8.21 0.246 52.7, 87.0 2.08
SM/J m 22.2 9.4   4 4.7 0.423 16.6, 36.2 -0.34
SWR/J m 35.5 6.91   4 3.45 0.194 27.5, 42.5 0.39
WSB/EiJ m 57.8 22.2   3 12.8 0.385 35.7, 80.2 1.6


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 8.5525 5.7788 20.0189 0.0
129X1/SvJ m 42.9025 5.7788 54.3689 31.4361
A/J m 16.43 5.7788 27.8964 4.9636
AKR/J m 26.845 5.7788 38.3114 15.3786
BALB/cByJ m 57.1625 5.7788 68.6289 45.6961
BTBR T+ Itpr3tf/J m 8.005 5.7788 19.4714 0.0
C3H/HeJ m 21.82 5.7788 33.2864 10.3536
C57BL/6J m 17.6625 5.7788 29.1289 6.1961
C57BLKS/J m 29.055 5.7788 40.5214 17.5886
C57BR/cdJ m 35.3275 5.7788 46.7939 23.8611
C58/J m 13.335 8.1725 29.5509 0.0
CBA/J m 47.2675 5.7788 58.7339 35.8011
CZECHII/EiJ m 16.085 5.7788 27.5514 4.6186
DBA/2J m 66.2025 5.7788 77.6689 54.7361
FVB/NJ m 25.755 5.7788 37.2214 14.2886
KK/HlJ m 15.12 5.7788 26.5864 3.6536
LG/J m 20.665 5.7788 32.1314 9.1986
LP/J m 10.0875 5.7788 21.5539 0.0
MA/MyJ m 12.8575 5.7788 24.3239 1.3911
NOD/ShiLtJ m 5.1425 5.7788 16.6089 0.0
NON/ShiLtJ m 15.6825 5.7788 27.1489 4.2161
NZB/BlNJ m 49.8425 5.7788 61.3089 38.3761
NZO/HlLtJ m 24.5975 5.7788 36.0639 13.1311
NZW/LacJ m 29.2075 5.7788 40.6739 17.7411
PERA/EiJ m 12.0825 5.7788 23.5489 0.6161
PL/J m 47.6525 5.7788 59.1189 36.1861
PWD/PhJ m 64.68 5.7788 76.1464 53.2136
PWK/PhJ m 13.48 5.7788 24.9464 2.0136
RIIIS/J m 8.5575 5.7788 20.0239 0.0
SEA/GnJ m 30.315 5.7788 41.7814 18.8486
SJL/J m 66.59 5.7788 78.0564 55.1236
SM/J m 22.2125 5.7788 33.6789 10.7461
SWR/J m 35.5225 5.7788 46.9889 24.0561
WSB/EiJ m 57.7533 6.6728 70.9936 44.5131




  GWAS USING LINEAR MIXED MODELS