Project measure / variable:   Wiltshire4   Bcells_Sel_D

ID, description, units MPD:52465   Bcells_Sel_D   B cells, percent viability   [%]  dose: 11.1 µM  
selumetinib study
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - B cells, percent viability dose: 11.1 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested34 strains
Mean of the strain means94.4   %
Median of the strain means96.3   %
SD of the strain means± 14.0
Coefficient of variation (CV)0.149
Min–max range of strain means60.5   –   142   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 26129.2416 791.7952 2.2853 0.0009
Residuals 99 34300.6219 346.4709


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 101.0 3.04   4 1.52 0.03 97.7, 104.0 0.47
129X1/SvJ m 98.0 9.35   4 4.68 0.0954 91.3, 112.0 0.26
A/J m 94.7 8.16   4 4.08 0.0862 85.4, 105.0 0.02
AKR/J m 103.0 7.16   4 3.58 0.0694 93.5, 109.0 0.61
BALB/cByJ m 100.0 3.63   4 1.81 0.0362 95.2, 104.0 0.4
BTBR T+ Itpr3tf/J m 64.2 20.2   4 10.1 0.314 39.5, 87.7 -2.15
BUB/BnJ m 98.0 11.8   4 5.92 0.121 85.8, 113.0 0.26
C3H/HeJ m 94.2 6.02   4 3.01 0.0639 87.6, 99.7 -0.01
C57BL/6J m 96.2 4.71   4 2.35 0.0489 90.9, 102.0 0.13
C57BLKS/J m 80.4 13.8   4 6.91 0.172 64.5, 94.0 -0.99
C58/J m 100.0 2.4   2   1.69 0.0239 98.7, 102.0 0.4
CBA/J m 91.4 47.2   4 23.6 0.516 60.7, 162.0 -0.21
CZECHII/EiJ m 96.5 17.4   4 8.7 0.18 79.7, 121.0 0.15
DBA/2J m 79.4 40.5   4 20.2 0.51 40.1, 133.0 -1.07
FVB/NJ m 103.0 14.3   4 7.13 0.138 82.7, 114.0 0.61
I/LnJ m 101.0 25.9   4 12.9 0.257 64.4, 123.0 0.47
KK/HlJ m 90.9 5.85   4 2.93 0.0644 85.6, 99.2 -0.25
LG/J m 106.0 32.8   4 16.4 0.308 66.7, 133.0 0.83
LP/J m 98.5 11.8   4 5.88 0.119 87.9, 110.0 0.29
MA/MyJ m 87.1 6.62   4 3.31 0.076 78.6, 93.9 -0.52
NOD/ShiLtJ m 87.6 17.6   4 8.81 0.201 64.0, 103.0 -0.48
NON/ShiLtJ m 94.0 16.4   4 8.2 0.175 75.6, 111.0 -0.03
NZB/BlNJ m 97.1 3.33   4 1.67 0.0343 94.7, 102.0 0.19
NZO/HlLtJ m 73.0 27.1   4 13.6 0.372 39.2, 105.0 -1.52
NZW/LacJ m 60.5 6.22   4 3.11 0.103 52.5, 66.7 -2.41
PERA/EiJ m 85.8 11.0   4 5.49 0.128 73.2, 95.4 -0.61
PL/J m 88.7 18.4   4 9.19 0.207 71.1, 109.0 -0.4
PWD/PhJ m 142.0 30.9   4 15.4 0.217 96.7, 164.0 3.39
PWK/PhJ m 101.0 3.34   4 1.67 0.0332 96.4, 104.0 0.47
RIIIS/J m 101.0 2.22   4 1.11 0.022 98.1, 103.0 0.47
SEA/GnJ m 91.5 20.9   4 10.5 0.229 70.7, 119.0 -0.2
SJL/J m 85.9 22.9   4 11.4 0.266 61.8, 111.0 -0.6
SM/J m 112.0 13.2   4 6.61 0.118 92.9, 122.0 1.25
WSB/EiJ m 105.0 14.9   3 8.61 0.143 90.5, 120.0 0.76


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 101.25 9.3069 119.7168 82.7832
129X1/SvJ m 98.03 9.3069 116.4968 79.5632
A/J m 94.72 9.3069 113.1868 76.2532
AKR/J m 103.25 9.3069 121.7168 84.7832
BALB/cByJ m 100.2425 9.3069 118.7093 81.7757
BTBR T+ Itpr3tf/J m 64.195 9.3069 82.6618 45.7282
BUB/BnJ m 97.9675 9.3069 116.4343 79.5007
C3H/HeJ m 94.2275 9.3069 112.6943 75.7607
C57BL/6J m 96.2225 9.3069 114.6893 77.7557
C57BLKS/J m 80.395 9.3069 98.8618 61.9282
C58/J m 100.365 13.1619 126.4811 74.2489
CBA/J m 91.3625 9.3069 109.8293 72.8957
CZECHII/EiJ m 96.465 9.3069 114.9318 77.9982
DBA/2J m 79.3525 9.3069 97.8193 60.8857
FVB/NJ m 103.4275 9.3069 121.8943 84.9607
I/LnJ m 100.655 9.3069 119.1218 82.1882
KK/HlJ m 90.865 9.3069 109.3318 72.3982
LG/J m 106.4 9.3069 124.8668 87.9332
LP/J m 98.5375 9.3069 117.0043 80.0707
MA/MyJ m 87.135 9.3069 105.6018 68.6682
NOD/ShiLtJ m 87.555 9.3069 106.0218 69.0882
NON/ShiLtJ m 93.955 9.3069 112.4218 75.4882
NZB/BlNJ m 97.0625 9.3069 115.5293 78.5957
NZO/HlLtJ m 72.9625 9.3069 91.4293 54.4957
NZW/LacJ m 60.545 9.3069 79.0118 42.0782
PERA/EiJ m 85.8025 9.3069 104.2693 67.3357
PL/J m 88.6875 9.3069 107.1543 70.2207
PWD/PhJ m 142.46 9.3069 160.9268 123.9932
PWK/PhJ m 100.8375 9.3069 119.3043 82.3707
RIIIS/J m 100.59 9.3069 119.0568 82.1232
SEA/GnJ m 91.46 9.3069 109.9268 72.9932
SJL/J m 85.8625 9.3069 104.3293 67.3957
SM/J m 112.1875 9.3069 130.6543 93.7207
WSB/EiJ m 104.56 10.7466 125.8837 83.2363




  GWAS USING LINEAR MIXED MODELS