Project measure / variable:   Wiltshire4   monocytes_BEZ_E

ID, description, units MPD:52418   monocytes_BEZ_E   monocytes, percent viability   [%]  dose: 100 µM  
BEZ235 study
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - monocytes, percent viability dose: 100 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested34 strains
Mean of the strain means82.4   %
Median of the strain means82.3   %
SD of the strain means± 28.6
Coefficient of variation (CV)0.347
Min–max range of strain means45.5   –   205   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 90626.7073 2746.2639 15.4404 < 0.0001
Residuals 99 17608.3958 177.8626


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 112.0 19.5   4 9.77 0.174 83.1, 126.0 1.04
129X1/SvJ m 50.1 8.77   4 4.38 0.175 38.5, 59.0 -1.13
A/J m 54.7 12.4   4 6.2 0.227 40.4, 70.2 -0.97
AKR/J m 59.6 11.8   4 5.92 0.199 47.6, 73.6 -0.8
BALB/cByJ m 110.0 2.3   4 1.15 0.0208 108.0, 113.0 0.97
BTBR T+ Itpr3tf/J m 71.0 17.2   4 8.6 0.242 51.3, 93.2 -0.4
BUB/BnJ m 74.9 8.63   4 4.31 0.115 67.8, 87.4 -0.26
C3H/HeJ m 58.2 8.74   4 4.37 0.15 47.4, 68.4 -0.85
C57BL/6J m 59.7 15.1   4 7.57 0.254 38.3, 70.8 -0.79
C57BLKS/J m 91.6 13.3   4 6.67 0.146 81.7, 110.0 0.32
C58/J m 114.0 23.7   2   16.8 0.209 96.8, 130.0 1.11
CBA/J m 68.7 15.9   4 7.94 0.231 53.5, 90.9 -0.48
CZECHII/EiJ m 85.2 25.0   4 12.5 0.294 60.1, 109.0 0.1
DBA/2J m 68.2 41.6   4 20.8 0.61 33.0, 128.0 -0.5
FVB/NJ m 51.4 9.62   4 4.81 0.187 44.6, 65.5 -1.08
I/LnJ m 87.7 4.65   4 2.33 0.0531 80.7, 90.2 0.19
KK/HlJ m 79.1 7.18   4 3.59 0.0907 68.7, 84.7 -0.11
LG/J m 100.0 10.7   4 5.37 0.107 85.2, 108.0 0.62
LP/J m 79.5 3.79   4 1.9 0.0477 74.1, 82.4 -0.1
MA/MyJ m 89.0 4.28   4 2.14 0.0481 85.1, 94.2 0.23
NOD/ShiLtJ m 68.0 5.93   4 2.96 0.0871 62.8, 74.6 -0.5
NON/ShiLtJ m 72.7 4.29   4 2.14 0.059 67.6, 76.4 -0.34
NZB/BlNJ m 60.4 10.1   4 5.06 0.168 50.6, 74.4 -0.77
NZO/HlLtJ m 87.8 3.73   4 1.86 0.0425 82.6, 91.5 0.19
NZW/LacJ m 92.6 7.74   4 3.87 0.0836 82.6, 101.0 0.36
PERA/EiJ m 89.0 6.98   4 3.49 0.0785 83.0, 98.5 0.23
PL/J m 93.0 8.85   4 4.43 0.0952 81.6, 103.0 0.37
PWD/PhJ m 99.5 17.3   4 8.67 0.174 76.2, 118.0 0.6
PWK/PhJ m 91.0 5.42   4 2.71 0.0596 84.7, 96.8 0.3
RIIIS/J m 87.3 11.4   4 5.72 0.131 77.2, 98.6 0.17
SEA/GnJ m 45.5 13.4   4 6.71 0.295 26.5, 58.0 -1.29
SJL/J m 52.3 11.3   4 5.63 0.215 35.9, 61.0 -1.05
SM/J m 92.1 1.6   4 0.802 0.0174 90.1, 93.8 0.34
WSB/EiJ m 205.0 5.44   3 3.14 0.0265 199.0, 210.0 4.29


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 111.9375 6.6683 125.1688 98.7062
129X1/SvJ m 50.095 6.6683 63.3263 36.8637
A/J m 54.6925 6.6683 67.9238 41.4612
AKR/J m 59.58 6.6683 72.8113 46.3487
BALB/cByJ m 110.3325 6.6683 123.5638 97.1012
BTBR T+ Itpr3tf/J m 71.02 6.6683 84.2513 57.7887
BUB/BnJ m 74.9075 6.6683 88.1388 61.6762
C3H/HeJ m 58.2025 6.6683 71.4338 44.9712
C57BL/6J m 59.6575 6.6683 72.8888 46.4262
C57BLKS/J m 91.6 6.6683 104.8313 78.3687
C58/J m 113.61 9.4303 132.3218 94.8982
CBA/J m 68.705 6.6683 81.9363 55.4737
CZECHII/EiJ m 85.2025 6.6683 98.4338 71.9712
DBA/2J m 68.1825 6.6683 81.4138 54.9512
FVB/NJ m 51.4075 6.6683 64.6388 38.1762
I/LnJ m 87.6825 6.6683 100.9138 74.4512
KK/HlJ m 79.115 6.6683 92.3463 65.8837
LG/J m 100.3475 6.6683 113.5788 87.1162
LP/J m 79.53 6.6683 92.7613 66.2987
MA/MyJ m 89.045 6.6683 102.2763 75.8137
NOD/ShiLtJ m 68.0225 6.6683 81.2538 54.7912
NON/ShiLtJ m 72.6825 6.6683 85.9138 59.4512
NZB/BlNJ m 60.4 6.6683 73.6313 47.1687
NZO/HlLtJ m 87.7575 6.6683 100.9888 74.5262
NZW/LacJ m 92.625 6.6683 105.8563 79.3937
PERA/EiJ m 89.0 6.6683 102.2313 75.7687
PL/J m 92.985 6.6683 106.2163 79.7537
PWD/PhJ m 99.5125 6.6683 112.7438 86.2812
PWK/PhJ m 91.0425 6.6683 104.2738 77.8112
RIIIS/J m 87.285 6.6683 100.5163 74.0537
SEA/GnJ m 45.5075 6.6683 58.7388 32.2762
SJL/J m 52.34 6.6683 65.5713 39.1087
SM/J m 92.09 6.6683 105.3213 78.8587
WSB/EiJ m 205.05 7.6998 220.3282 189.7718




  GWAS USING LINEAR MIXED MODELS